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Amazon One Medical vs Good Girl Rx

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Amazon One Medical logo

Amazon One Medical

8.5
★★★★4.3/5

Best for: the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings

Visit Amazon One Medical
VS
Good Girl Rx logo

Good Girl Rx

7.2
★★★3.6/5

Best for: patients seeking multiple compounded GLP-1 formats with pharmacy quality standards

Visit Good Girl Rx

Amazon One Medical and Good Girl Rx are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Good Girl Rx starts lower at $79/mo versus $149/mo, and Amazon One Medical edges ahead overall (8.5 vs 7.2 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Amazon One Medical

Foundayo (with insurance + Lilly Savings Card)Brand-name
$25/mo
orforglipron
Foundayo (cash pay)Brand-name
$149/mo
orforglipron

Good Girl Rx

Injectable (from)Compounded
$134/mo
semaglutide

From $134/mo on annual plan (monthly $179, quarterly $159; all paid upfront).

Microdose (from)Compounded
$79/mo
semaglutide

Semaglutide microdose, from $79/mo.

ODT pills (from)oral
$214/mo
semaglutide

Oral dissolving tablets, from $214/mo.

Injectable (from)Compounded
$235/mo
tirzepatide

From $235/mo.

Microdose (from)Compounded
$139/mo
tirzepatide

Tirzepatide microdose, from $139/mo.

Pills (from)oral
$291/mo
tirzepatide

Tirzepatide pills, from $291/mo.

Brand (from)Brand-name
$1580/mo
Ozempic

From $1,580/mo; limited availability.

Brand (from)Brand-name
$1991/mo
Wegovy

From $1,991/mo; limited availability.

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What’s included

Amazon One Medical

What the monthly price covers

Medication

Billed separately

Provider visits

Included

Shipping

Included

Lab work

Billed separately

Coaching

Not disclosed

Good Girl Rx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Amazon One Medical

8.5/10

Overall

Good Girl Rx

7.2/10

Value25%

8.5A
vs
B
7.0

Effectiveness25%

8.5A
vs
B
7.0

User Experience15%

8.0A
vs
B
7.5

Trust & Safety15%

8.8A
vs
B
7.8

Accessibility10%

9.5A
vs
B
7.0

Support10%

8.0A
vs
B
7.0

Features & Coverage

FeatureAmazon One MedicalGood Girl Rx
Starting Price$149/mo$79/mo
Features6 features7 features
States Available50Not disclosed
Compounded✓ Yes
Brand Name✓ Yes✓ Yes
FSA/HSA Accepted
FDA WarningsNoneNone

About Amazon One Medical

Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.

Read our full Amazon One Medical review →

About Good Girl Rx

Good Girl Rx (Good Girl LLC) offers compounded semaglutide and tirzepatide in injectable, microdose, and oral dissolving tablet (ODT) formats. Brand-name Ozempic, Wegovy, Zepbound, Mounjaro also listed (limited availability). LegitScript certified. Dispensed by licensed 503A/503B pharmacies. Founded by Savannah Chrisley.

Read our full Good Girl Rx review →

Pros & Cons

Amazon One Medical

What we like

  • As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
  • Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
  • In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
  • Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
  • Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
  • Delivering GLP-1 medications since 2021 — track record on cold-chain logistics

Watch-outs

  • Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
  • Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
  • Pricing is set by manufacturer savings programs and can change at any time
  • No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
  • Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
  • Copays and deductibles still apply to the clinical visit

Good Girl Rx

What we like

  • LegitScript certified
  • Multiple formats — injectable, microdose, and ODT pills — for both semaglutide and tirzepatide
  • Dispensed by licensed 503A or 503B pharmacies
  • Limited brand-name options available (Ozempic, Wegovy, Zepbound, Mounjaro)
  • Named legal entity with a Nashville address
  • Financing via Affirm, Klarna, and Afterpay

Watch-outs

  • State availability not disclosed
  • Very new brand — founded January 2025
  • Celebrity-founded (Savannah Chrisley) — brand vs clinical credibility

Our Verdict

Winner: Amazon One Medical

Amazon One Medical edges out Good Girl Rx with a higher overall score of 8.5/10 and is particularly strong for the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings. Good Girl Rx remains a solid alternative, especially if you're looking for patients seeking multiple compounded GLP-1 formats with pharmacy quality standards.

Choose Amazon One Medical if…

You want the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings and a starting price around $149/mo.

Choose Good Girl Rx if…

You want patients seeking multiple compounded GLP-1 formats with pharmacy quality standards and a starting price around $79/mo.

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7.7

TrimRx

Best overall value

7.6

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LegitScript-verified compounded GLP-1 via named pharmacies

7.5

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Men seeking flat-priced compounded GLP-1 access alongside TRT or peptide therapy

Amazon One Medical vs Good Girl Rx: FAQ

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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.