Amazon One Medical vs Effecty
In our scoring, Amazon One Medical edges ahead overall (8.5 vs 7.5 out of 10), and Amazon One Medical costs less for brand-name Wegovy / Ozempic (about $13,013 a year less; one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost).
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Key differences
- Price
- Amazon One Medical $199/mo vs Effecty $1,300/mo for brand-name Wegovy / Ozempic (standing prices, no prepay or separate membership listed · about $13,013 a year less with Amazon One Medical · one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
- Coverage
- Both serve the same 50 states
- Included
- Amazon One Medical: clinician visits, shipping (not included: medication, labs); Effecty: medication, clinician visits, shipping
Amazon One Medical
Best for brand-name GLP-1s with published per-dose cash prices and Amazon Pharmacy delivery
Brand-name Wegovy / Ozempic
$199
billed every 4 weeks
Our score 8.5/10
Effecty
Best for compounded semaglutide or tirzepatide month-to-month, with brand-name options on the same platform
semaglutide
$170
$95 first month
Our score 7.5/10
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Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
Amazon One Medical
Effecty
Price
Brand Wegovy / Ozempic / month
Better on this row: $199/mo
billed every 4 weeks
$1,300/mo
Brand Wegovy / Ozempic / year (modeled)
Better on this row: $2,587
13 charges
$15,600
Brand Zepbound / Mounjaro / month
Better on this row: $299/mo
billed every 4 weeks
$1,300/mo
Brand Zepbound / Mounjaro / year (modeled)
Better on this row: $3,887
13 charges
$15,600
Semaglutide / month
Not listed
$170/mo
$95 first month
Tirzepatide / month
Not listed
$235/mo
$160 first month
Brand Wegovy pill / Rybelsus / month
$149/mo
Not listed
Brand Foundayo / month
$149/mo
Not listed
Coverage
State availability
50 states
50 states
Oral option listed
Yes
Not listed
Brand-name access listed
Wegovy / Ozempic, Zepbound / Mounjaro, Wegovy pill / Rybelsus, Foundayo
Wegovy / Ozempic, Zepbound / Mounjaro
Included in the price
Clinician visits, shipping
Not included: medication, labs
Medication, clinician visits, shipping
Terms & safety
Price shown
Before intake
Before intake
Lab work
Required
Not disclosed
Cancel anytime
Not disclosed
Yes
Minimum commitment
Not disclosed
None
Refunds
Not disclosed
No refunds; all sales final
FDA warning letters
None on record
None on record
Provider facts checked
October 2026
October 2026
Every dose and plan: Amazon One Medical · Effecty
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose Amazon One Medical if…
- About $13,013 a year less than Effecty for brand-name Wegovy / Ozempic at standing prices (one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
- Lists brand-name Wegovy pill / Rybelsus and brand-name Foundayo, which Effecty doesn't price
- Publishes cash prices for every GLP-1 dose up front, with manufacturer coupons applied automatically if eligible
What to weigh up
- Price doesn't include medication
- Online On-Demand Care is cash-only for medication; insurance needs scheduled visits near a One Medical office
Choose Effecty if…
- Lists compounded semaglutide and compounded tirzepatide, which Amazon One Medical doesn't price
- Price includes medication; Amazon One Medical's doesn't
- Compounded semaglutide and tirzepatide plus brand-name Ozempic, Wegovy, Zepbound, and Mounjaro
What to weigh up
- About $13,013 a year more than Amazon One Medical for brand-name Wegovy / Ozempic (one bills every 4 weeks (13 charges a year), so this compares modeled yearly cost)
- Brand-name options at full cash price ($1,300-$1,600/mo); no insurance billing
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Amazon One Medical
8.5/10
Effecty
7.5/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
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SkinnyRx
Compounded semaglutide or tirzepatide with the consult and free overnight shipping in one price
Read full review →From $149.25/mo
Get started →Collective
The lowest flat medication price if you can absorb an annual membership fee
Read full review →From $59/mo + membership
Get started →From $219/mo
Get started →Amazon One Medical vs Effecty: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.