Amazon One Medical vs Apex MD
An in-depth comparison of two leading GLP-1 Providers
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Amazon One Medical
Best for: the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings
Visit Amazon One Medical →Apex MD
Best for: people who want nationwide access to compounded glp-1 with unlimited visits and labs included
Visit Apex MD →Amazon One Medical and Apex MD are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Amazon One Medical starts lower at $149/mo versus $299/mo, and Amazon One Medical edges ahead overall (8.5 vs 7.2 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
Amazon One Medical
Apex MD
weekly injection, includes NAD/B-12/L-Carnitine, month-to-month
weekly injection, month-to-month
daily oral
daily oral
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What’s included
Amazon One Medical
What the monthly price covers
Medication
Billed separately
Provider visits
Included
Shipping
Included
Lab work
Billed separately
Coaching
Not disclosed
Apex MD
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Amazon One Medical
8.5/10
Apex MD
7.2/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Amazon One Medical | Apex MD |
|---|---|---|
| Starting Price | ✓$149/mo | $299/mo |
| Features | 6 features | ✓8 features |
| States Available | 50 | ✓51 |
| Compounded | — | ✓ Yes |
| Brand Name | ✓ Yes | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About Amazon One Medical
Amazon One Medical is the unified Amazon GLP-1 channel — One Medical clinicians prescribe FDA-approved Wegovy, Zepbound, and Foundayo (no compounded products), and Amazon Pharmacy fulfills with same-day delivery across roughly 3,000 US cities plus pickup kiosks at select One Medical locations. No prior membership required; insurance and cash pay both accepted. Foundayo launched at $25/month with insurance and the Lilly Savings Card, or $149/month cash pay.
Read our full Amazon One Medical review →About Apex MD
Apex MD is a US virtual telemedicine platform licensed in all 50 states that prescribes compounded GLP-1 medications for weight loss. Weekly injections are 299 dollars per month for compounded semaglutide and 399 dollars per month for compounded tirzepatide; daily oral versions are 349 dollars per month for semaglutide and 419 dollars per month for tirzepatide. Compounds are formulated with added NAD, B-12 and L-Carnitine. Plans include unlimited provider visits and Labcorp labs at no extra fee, with medication delivery typically in under four business days. GLP-1 microdosing is also offered.
Read our full Apex MD review →Pros & Cons
Amazon One Medical
What we like
- As low as $1/day ($25/month) for brand-name Foundayo with insurance and the auto-applied Lilly coupon
- Same-day delivery in nearly 3,000 US cities at launch, expanding to 4,500 by end of 2026
- In-office pharmacist kiosks at select One Medical clinics let you walk out with Foundayo in hand
- Cash-pay $5/day ($149/month) is competitive for the same FDA-approved brand-name product
- Real-time availability, transparent pricing, and automatic manufacturer coupon at checkout
- Delivering GLP-1 medications since 2021 — track record on cold-chain logistics
Watch-outs
- Headline $25/month needs both insurance and the Lilly Savings Card — uninsured pay $149/month
- Same-day delivery is geographically gated; outside major cities it drops to next-day or slower
- Pricing is set by manufacturer savings programs and can change at any time
- No compounded options — brand-name only (Foundayo, Wegovy, Zepbound)
- Wegovy/Zepbound pricing isn't shown upfront — depends on insurance at the prescribing visit
- Copays and deductibles still apply to the clinical visit
Apex MD
What we like
- Licensed in all 50 states
- Unlimited provider visits and Labcorp labs included in the plan
- Both semaglutide and tirzepatide, injectable or oral
- Medication delivery typically in under four business days
Watch-outs
- Compounds bundle NAD, B-12 and L-Carnitine rather than a single-ingredient GLP-1
- Does not publicly name its compounding pharmacy or list an accreditation seal
Our Verdict
Amazon One Medical edges out Apex MD with a higher overall score of 8.5/10 and is particularly strong for the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings. Apex MD remains a solid alternative, especially if you're looking for people who want nationwide access to compounded glp-1 with unlimited visits and labs included.
Choose Amazon One Medical if…
You want the most authoritative branded GLP-1 channel with same-day delivery and integrated manufacturer savings and a starting price around $149/mo.
Choose Apex MD if…
You want people who want nationwide access to compounded glp-1 with unlimited visits and labs included and a starting price around $299/mo.
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Get started →Amazon One Medical vs Apex MD: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.