1st Optimal vs Revive Longevity
An in-depth comparison of two leading GLP-1 Providers
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1st Optimal
Best for: GLP-1 therapy within a lab-driven functional-medicine program
Visit 1st Optimal →Revive Longevity
Best for: tirzepatide buyers who want the compounding pharmacy named up front
Visit Revive Longevity →1st Optimal and Revive Longevity are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 1st Optimal starts lower at $99/mo versus $250/mo, and Revive Longevity edges ahead overall (7.3 vs 6.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
1st Optimal
Care membership only — the GLP-1 medication is billed separately and is not priced.
Revive Longevity
Subscription rate, "Save $20 every month vs the one-time supply price". A 4-week cycle means 13 charges a year, not 12.
Single one-time purchase, no subscription.
$749 is charged once, not monthly — labelled "BEST VALUE · SAVE $148". Works out at $249.67/mo.
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What’s included
1st Optimal
What the monthly price covers
Medication
Not disclosed
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Included
Revive Longevity
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
1st Optimal
6.7/10
Revive Longevity
7.3/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | 1st Optimal | Revive Longevity |
|---|---|---|
| Starting Price | ✓$99/mo | $250/mo |
| Features | ✓8 features | 5 features |
| States Available | Not disclosed | Not disclosed |
| Compounded | — | ✓ Yes |
| Brand Name | ✓ Yes | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About 1st Optimal
1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets. Its model pairs prescription GLP-1 therapy with at-home lab testing, blood-work interpretation, unlimited coaching, and personalized protocols framed around long-term weight loss and longevity. Care is delivered virtually by credentialed providers, and treatments ship to the home with no long-term contracts. The site does not publish monthly pricing or a state list.
Read our full 1st Optimal review →About Revive Longevity
Revive Longevity is a Florida telehealth practice offering compounded tirzepatide at $279 every four weeks on subscription, or $299 for a single month. It names its compounding pharmacy — Strive Pharmacy in Gilbert, Arizona — which most compounded GLP-1 sellers do not, and your card is only authorized at checkout rather than charged until a provider approves the plan. It does not sell semaglutide.
Read our full Revive Longevity review →Pros & Cons
1st Optimal
What we like
- Offers both semaglutide and tirzepatide with injectable and oral formats
- Functional-medicine approach with at-home labs and blood-work interpretation
- Unlimited coaching and ongoing support included
- No long-term contracts
- Board-certified doctors and nurse practitioners referenced
Watch-outs
- No public monthly pricing disclosed
- No published state availability list
- Compounded vs branded sourcing not clarified on site
- Pricing only revealed after quiz or consultation
Revive Longevity
What we like
- Names its compounding pharmacy: Strive Pharmacy, Gilbert AZ, 503A and PCAB/NABP/LegitScript accredited
- Your card is only authorized at checkout — "you are not charged until a licensed provider approves your plan"
- Three ways to buy: rolling subscription, a single month, or a discounted 3-month supply
- Publishes a phone number as well as email support
- States its BMI requirement up front rather than after intake
- Ships in 1-2 days after approval
Watch-outs
- Tirzepatide only — no semaglutide anywhere on the site, so no cheaper first-line option
- The subscription bills every 4 weeks, which is 13 charges a year rather than 12
- No refunds once a prescription has been approved or sent to the pharmacy
- How the $299/$599/$999 membership tiers relate to the medication price is never explained
- No published state list beyond a claim of all 50 states in the FAQ
Our Verdict
Revive Longevity edges out 1st Optimal with a higher overall score of 7.3/10 and is particularly strong for tirzepatide buyers who want the compounding pharmacy named up front. 1st Optimal remains a solid alternative, especially if you're looking for GLP-1 therapy within a lab-driven functional-medicine program.
Choose 1st Optimal if…
You want GLP-1 therapy within a lab-driven functional-medicine program and a starting price around $99/mo.
Choose Revive Longevity if…
You want tirzepatide buyers who want the compounding pharmacy named up front and a starting price around $250/mo.
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TrimRx
Best overall value
From $149/mo
Get started →Sprout Health
LegitScript-certified compounded GLP-1 via named pharmacies
From $149/mo
Get started →Care Bare Rx
LGBTQ+-inclusive compounded GLP-1 telehealth
From $199/mo
Get started →1st Optimal vs Revive Longevity: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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