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1st Optimal vs QuickMD

Name: 1st Optimal
Brand: 1st Optimal
Availability: OnlineOnly

An in-depth comparison of two leading GLP-1 Providers

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6.7

1st Optimal

Best for Patients wanting GLP-1 therapy within a lab-driven functional-medicine program

★★★☆☆3.4

Semaglutide GLP-1Tirzepatide GLP-1Oral tablet optionAt-home lab testing

Visit 1st Optimal →

7.3

QuickMD

Best for Cost-conscious patients wanting same-day compounded or brand GLP-1 access

★★★★☆3.7

Starting at $279/mo

Compounded sema ~$279Brand GLP-1 Rx tooSame-day visits45+ states

Visit QuickMD →

Side-by-Side Comparison

Feature	1st Optimal	QuickMD
Overall Score	6.7/10	✓7.3/10
Starting Price	—	$279/mo
Editorial Rating	3.4 ★ /5	✓3.7 ★ /5
Features	8 features	8 features
States Available	0	0
Compounded	—	✓ Yes
Brand Name	—	—
FSA/HSA Accepted	—	—
FDA Warnings	None	None

Pros & Cons

1st Optimal

Pros

✓Offers both semaglutide and tirzepatide with injectable and oral formats
✓Functional-medicine approach with at-home labs and blood-work interpretation
✓Unlimited coaching and ongoing support included
✓No long-term contracts
✓Board-certified doctors and nurse practitioners referenced

Cons

✗No public monthly pricing disclosed
✗No published state availability list
✗Compounded vs branded sourcing not clarified on site
✗Pricing only revealed after quiz or consultation

QuickMD

Pros

✓Compounded semaglutide around $279/mo plus brand-name GLP-1 options
✓Same-day, 365-day-a-year online visits
✓Large established platform with over 1 million completed visits
✓Transparent cash-pay pricing with reimbursement summaries
✓Can prescribe Wegovy, Zepbound, Ozempic, Mounjaro, Rybelsus

Cons

✗Does not accept insurance
✗Available in 45+ states, not all 50
✗Medication cost varies by pharmacy, not fully bundled
✗No named board-certified physicians listed publicly

Our Verdict

Winner: QuickMDScore: 7.3/10

QuickMD edges out 1st Optimal with a higher overall score of 7.3/10 and is particularly strong for Cost-conscious patients wanting same-day compounded or brand GLP-1 access. 1st Optimal remains a solid alternative, especially if you're looking for Patients wanting GLP-1 therapy within a lab-driven functional-medicine program.

Get Started with 1st Optimal →Get Started with QuickMD →

Glossary references

Key terms in this article, linked to their canonical definitions.

Semaglutide · Drugs and brands
Tirzepatide · Drugs and brands
Compounded GLP-1 · Pharmacy and drug forms
503A pharmacy · Pharmacy and drug forms
PCAB accreditation · Pharmacy and drug forms
Prior authorization (PA) · Insurance and regulatory
Off-label use · Insurance and regulatory
FDA Drug Shortage List · Insurance and regulatory

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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.