1st Optimal vs QuickMD
An in-depth comparison of two leading GLP-1 Providers
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1st Optimal
Best for: Patients wanting GLP-1 therapy within a lab-driven functional-medicine program
Visit 1st Optimal →
QuickMD
Best for: Cost-conscious patients wanting same-day compounded or brand GLP-1 access
Visit QuickMD →1st Optimal and QuickMD are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, QuickMD starts at $279/mo, and QuickMD edges ahead overall (7.4 vs 6.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
1st Optimal
Pricing not publicly listed.
QuickMD
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Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
1st Optimal
6.7/10
QuickMD
7.4/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | 1st Optimal | QuickMD |
|---|---|---|
| Starting Price | — | $279/mo |
| Features | 8 features | 8 features |
| States Available | Not disclosed | Not disclosed |
| Compounded | — | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About 1st Optimal
1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets. Its model pairs prescription GLP-1 therapy with at-home lab testing, blood-work interpretation, unlimited coaching, and personalized protocols framed around long-term weight loss and longevity. Care is delivered virtually by credentialed providers, and treatments ship to the home with no long-term contracts. The site does not publish monthly pricing or a state list.
Read our full 1st Optimal review →About QuickMD
QuickMD is a high-volume telemedicine platform (over 1 million visits) offering same-day online weight-management care. It provides compounded semaglutide for about $279 per month and can prescribe brand-name GLP-1s including Wegovy, Zepbound, Ozempic, Mounjaro and oral Rybelsus, with medication costs varying by pharmacy. Visits are conducted entirely online by phone or video with licensed clinicians, available 365 days a year in 45-plus states. QuickMD uses transparent cash-pay pricing and does not bill insurance, though it provides visit summaries for possible reimbursement.
Read our full QuickMD review →Pros & Cons
1st Optimal
What we like
- Offers both semaglutide and tirzepatide with injectable and oral formats
- Functional-medicine approach with at-home labs and blood-work interpretation
- Unlimited coaching and ongoing support included
- No long-term contracts
- Board-certified doctors and nurse practitioners referenced
Watch-outs
- No public monthly pricing disclosed
- No published state availability list
- Compounded vs branded sourcing not clarified on site
- Pricing only revealed after quiz or consultation
QuickMD
What we like
- Compounded semaglutide around $279/mo plus brand-name GLP-1 options
- Same-day, 365-day-a-year online visits
- Large established platform with over 1 million completed visits
- Transparent cash-pay pricing with reimbursement summaries
- Can prescribe Wegovy, Zepbound, Ozempic, Mounjaro, Rybelsus
Watch-outs
- Does not accept insurance
- Available in 45+ states, not all 50
- Medication cost varies by pharmacy, not fully bundled
- No named board-certified physicians listed publicly
Our Verdict
QuickMD edges out 1st Optimal with a higher overall score of 7.4/10 and is particularly strong for Cost-conscious patients wanting same-day compounded or brand GLP-1 access. 1st Optimal remains a solid alternative, especially if you're looking for Patients wanting GLP-1 therapy within a lab-driven functional-medicine program.
Choose 1st Optimal if…
You want Patients wanting GLP-1 therapy within a lab-driven functional-medicine program.
Choose QuickMD if…
You want Cost-conscious patients wanting same-day compounded or brand GLP-1 access and a starting price around $279/mo.
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Wellorithm
Compounded GLP-1 access with oral tablet options across 49 states
From $147/mo
Get started →SkinnyRx
Mainstream telehealth GLP-1 access
From $149.25/mo
Get started →Sunlight
Compounded GLP-1 with unlimited telehealth visits and free shipping
From $159/mo
Get started →1st Optimal vs QuickMD: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.