1st Optimal vs NEUVÉ Health
An in-depth comparison of two leading GLP-1 Providers
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1st Optimal
Best for: GLP-1 therapy within a lab-driven functional-medicine program
Visit 1st Optimal →NEUVÉ Health
Best for: a broad catalog of GLP-1, hormone and peptide protocols under one brand
Visit NEUVÉ Health →1st Optimal and NEUVÉ Health are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 1st Optimal starts lower at $99/mo versus $160/mo, and 1st Optimal edges ahead overall (6.7 vs 6.6 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
1st Optimal
Care membership only — the GLP-1 medication is billed separately and is not priced.
NEUVÉ Health
Program fee. Site contradicts itself on whether medication is included.
Program fee. Site contradicts itself on whether medication is included.
Recommended plan at intake. Program fee; medication billed separately per fine print.
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What’s included
1st Optimal
What the monthly price covers
Medication
Not disclosed
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Included
NEUVÉ Health
Inclusions not disclosed.
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
1st Optimal
6.7/10
NEUVÉ Health
6.6/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | 1st Optimal | NEUVÉ Health |
|---|---|---|
| Starting Price | ✓$99/mo | $160/mo |
| Features | ✓8 features | 1 features |
| States Available | Not disclosed | Not disclosed |
| Compounded | — | ✓ Yes |
| Brand Name | ✓ Yes | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About 1st Optimal
1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets. Its model pairs prescription GLP-1 therapy with at-home lab testing, blood-work interpretation, unlimited coaching, and personalized protocols framed around long-term weight loss and longevity. Care is delivered virtually by credentialed providers, and treatments ship to the home with no long-term contracts. The site does not publish monthly pricing or a state list.
Read our full 1st Optimal review →About NEUVÉ Health
NEUVÉ Health (neuvemd.com) is a physician-led telehealth brand offering compounded GLP-1 weight-loss protocols alongside hormone optimization, peptides, men's health and lab panels. Its public pricing page advertises GLP-1 from $138 a month, but the real plans appear only after a completed intake and start at $160. The figures are billed every 28 days rather than monthly, and the site contradicts itself over whether the medication is included in them.
Read our full NEUVÉ Health review →Pros & Cons
1st Optimal
What we like
- Offers both semaglutide and tirzepatide with injectable and oral formats
- Functional-medicine approach with at-home labs and blood-work interpretation
- Unlimited coaching and ongoing support included
- No long-term contracts
- Board-certified doctors and nurse practitioners referenced
Watch-outs
- No public monthly pricing disclosed
- No published state availability list
- Compounded vs branded sourcing not clarified on site
- Pricing only revealed after quiz or consultation
NEUVÉ Health
What we like
- Shows three named plans with prices immediately after intake, rather than making you create an account first
- States that there is no consultation fee and no charge until a licensed clinician approves the plan
- Broad catalog beyond GLP-1s — hormone therapy, peptides, men's health and lab panels under one brand
- Editorial guides on its own site name the molecules and compare them rather than only selling
Watch-outs
- Contradicts itself on whether medication is included — the fine print says billed separately, the What-s Included panel says included
- The advertised from $138/mo matches no real plan — the cheapest option after intake is $160
- States served are not enumerated anywhere on the site
- No dispensing pharmacy named and no LegitScript badge displayed
- Billed every 28 days, not monthly — 13 charges a year, and payment can precede the final questionnaire or lab visit
Our Verdict
1st Optimal edges out NEUVÉ Health with a higher overall score of 6.7/10 and is particularly strong for GLP-1 therapy within a lab-driven functional-medicine program. NEUVÉ Health remains a solid alternative, especially if you're looking for a broad catalog of GLP-1, hormone and peptide protocols under one brand.
Choose 1st Optimal if…
You want GLP-1 therapy within a lab-driven functional-medicine program and a starting price around $99/mo.
Choose NEUVÉ Health if…
You want a broad catalog of GLP-1, hormone and peptide protocols under one brand and a starting price around $160/mo.
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Wellorithm
Compounded GLP-1 access with oral tablet options across 49 states
From $147/mo
Get started →SkinnyRx
Mainstream telehealth GLP-1 access
From $149.25/mo
Get started →Sesame Care
Brand-name GLP-1s at cash prices, no compounding
From $25/mo
Get started →1st Optimal vs NEUVÉ Health: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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