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1st Optimal vs Nava Health

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
1st Optimal logo

1st Optimal

6.7
★★★☆☆3.4/5

Best for: GLP-1 therapy within a lab-driven functional-medicine program

Visit 1st Optimal
VS
Nava Health logo

Nava Health

6.7
★★★☆☆3.4/5

Best for: GLP-1 weight loss inside a functional-medicine program with lab testing

Visit Nava Health

1st Optimal and Nava Health are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 1st Optimal starts at $99/mo, and both land at 6.7/10 overall. Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

1st Optimal

Weight Loss Care membership — medication not includedBrand-name
$99/mo
semaglutide

Care membership only — the GLP-1 medication is billed separately and is not priced.

Nava Health

Pricing not publicly listed.

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What’s included

1st Optimal

What the monthly price covers

Medication

Not disclosed

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Included

Nava Health

What the monthly price covers

Medication

Not disclosed

Provider visits

Billed separately

Shipping

Not disclosed

Lab work

Billed separately

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

1st Optimal

6.7/10

Overall

Nava Health

6.7/10

Value25%

6.5A
vs
B
6.0

Effectiveness25%

7.0A
vs
B
7.0

User Experience15%

6.5A
vs
B
7.0

Trust & Safety15%

6.5A
vs
B
7.0

Accessibility10%

6.5A
vs
B
6.5

Support10%

7.4A
vs
B
7.4

Features & Coverage

Feature1st OptimalNava Health
Starting Price$99/mo
Features8 features8 features
States AvailableNot disclosedNot disclosed
Compounded
Brand Name✓ Yes
FSA/HSA Accepted
FDA WarningsNoneNone

About 1st Optimal

1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets. Its model pairs prescription GLP-1 therapy with at-home lab testing, blood-work interpretation, unlimited coaching, and personalized protocols framed around long-term weight loss and longevity. Care is delivered virtually by credentialed providers, and treatments ship to the home with no long-term contracts. The site does not publish monthly pricing or a state list.

Read our full 1st Optimal review →

About Nava Health

Nava Health is a functional and integrative medicine practice offering its NavaRX medical weight loss program with GLP-1 medications (semaglutide and tirzepatide, brand or compounded). Care combines advanced lab testing, nutrition coaching, and hormone-aware treatment delivered via telemedicine or at centers in Maryland and Virginia. The clinic is cash-based with upfront pricing, financing, and membership plans, and is staffed by board-certified MDs, DOs, NPs, PAs, and functional-medicine nutritionists. Specific GLP-1 prices are not published online and depend on a consultation plus lab work.

Read our full Nava Health review →

Pros & Cons

1st Optimal

What we like

  • Offers both semaglutide and tirzepatide with injectable and oral formats
  • Functional-medicine approach with at-home labs and blood-work interpretation
  • Unlimited coaching and ongoing support included
  • No long-term contracts
  • Board-certified doctors and nurse practitioners referenced

Watch-outs

  • No public monthly pricing disclosed
  • No published state availability list
  • Compounded vs branded sourcing not clarified on site
  • Pricing only revealed after quiz or consultation

Nava Health

What we like

  • Integrative functional-medicine approach with advanced lab testing
  • Both telemedicine and in-person options
  • Board-certified MDs, DOs, NPs, PAs, and nutritionists
  • Offers both brand and compounded GLP-1 formulations
  • Financing and membership plans available

Watch-outs

  • No published GLP-1 medication pricing online
  • Consultation plus lab work adds to total cost
  • Bundled integrative model costs more than medication-only platforms
  • State availability for telehealth not clearly listed

Our Verdict

Both 1st Optimal and Nava Health score equally well overall — the right choice depends on your priorities.

Choose 1st Optimal if…

You want GLP-1 therapy within a lab-driven functional-medicine program and a starting price around $99/mo.

Choose Nava Health if…

You want GLP-1 weight loss inside a functional-medicine program with lab testing.

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7.3

Sunlight

Compounded GLP-1 with unlimited telehealth visits and free shipping

7.4

MadeMed

Compounded GLP-1 in both injection and oral forms

8.3

Found

Mainstream telehealth GLP-1 access

1st Optimal vs Nava Health: FAQ

1st Optimal lists a lowest ongoing price of $99/mo, while Nava Health does not publicly list one. See the side-by-side pricing above for the full breakdown.
1st Optimal and Nava Health tie at 6.7/10 overall, so the right pick comes down to your priorities — 1st Optimal for GLP-1 therapy within a lab-driven functional-medicine program, Nava Health for GLP-1 weight loss inside a functional-medicine program with lab testing.
Neither 1st Optimal nor Nava Health publicly lists its exact state availability. Most national GLP-1 telehealth providers operate in the majority of states — confirm your state is covered during sign-up.
Neither 1st Optimal nor Nava Health is currently an affiliate partner, so we earn no commission from either. We rank all providers editorially using the same six-dimension framework and disclose any commercial relationships.

Key terms, explained

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Continue exploring 1st Optimal and Nava Health head-to-heads in the same category.

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