1st Optimal vs Näky
An in-depth comparison of two leading GLP-1 Providers
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1st Optimal
Best for: GLP-1 therapy within a lab-driven functional-medicine program
Visit 1st Optimal →
1st Optimal and Näky are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 1st Optimal starts lower at $99/mo versus $145/mo, and Näky edges ahead overall (7.0 vs 6.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
1st Optimal
Care membership only — the GLP-1 medication is billed separately and is not priced.
Näky
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What’s included
1st Optimal
What the monthly price covers
Medication
Not disclosed
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Included
Näky
What the monthly price covers
Medication
Not disclosed
Provider visits
Not disclosed
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
1st Optimal
6.7/10
Näky
7.0/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | 1st Optimal | Näky |
|---|---|---|
| Starting Price | ✓$99/mo | $145/mo |
| Features | 8 features | 8 features |
| States Available | Not disclosed | Not disclosed |
| Compounded | — | — |
| Brand Name | ✓ Yes | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About 1st Optimal
1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets. Its model pairs prescription GLP-1 therapy with at-home lab testing, blood-work interpretation, unlimited coaching, and personalized protocols framed around long-term weight loss and longevity. Care is delivered virtually by credentialed providers, and treatments ship to the home with no long-term contracts. The site does not publish monthly pricing or a state list.
Read our full 1st Optimal review →About Näky
Näky is a LegitScript-approved telehealth platform offering compounded semaglutide and tirzepatide alongside an uncommon oral semaglutide drops product and a separate GLP-1 microdose program, plus NAD+ and Sermorelin add-ons. Onboarding runs through a 3-minute online assessment with a same-day treatment plan from a licensed provider. Steady-state pricing is gated behind intake; a NAKY10 promo code is referenced for the oral line.
Read our full Näky review →Pros & Cons
1st Optimal
What we like
- Offers both semaglutide and tirzepatide with injectable and oral formats
- Functional-medicine approach with at-home labs and blood-work interpretation
- Unlimited coaching and ongoing support included
- No long-term contracts
- Board-certified doctors and nurse practitioners referenced
Watch-outs
- No public monthly pricing disclosed
- No published state availability list
- Compounded vs branded sourcing not clarified on site
- Pricing only revealed after quiz or consultation
Näky
What we like
- LegitScript Approved (verifiable for benaky.com)
- Oral semaglutide drops as a distinct product line — uncommon among compounded GLP-1 brands
- Separate GLP-1 microdose program offered
- Adds NAD+ and Sermorelin for patients wanting a longevity stack
- 3-minute online assessment with a same-day treatment plan
- Promo code NAKY10 for the oral semaglutide line
Watch-outs
- Ongoing monthly pricing for compounded semaglutide and tirzepatide isn't shown until intake
- Oral semaglutide drops and microdose program pricing not disclosed
- Legal entity and state of incorporation not disclosed
- Pharmacy partner not named — only a generic 'USA-based FDA-regulated' claim
- States served not listed; pricing pages return 404s
- Compounded only — no brand-name GLP-1s; lab work and consult fees unclear
- Oral semaglutide drops are not Rybelsus or any FDA-approved oral formulation — ask about dose equivalence at intake
Our Verdict
Näky edges out 1st Optimal with a higher overall score of 7.0/10 and is particularly strong for compounded oral semaglutide drops plus a microdose program. 1st Optimal remains a solid alternative, especially if you're looking for GLP-1 therapy within a lab-driven functional-medicine program.
Choose 1st Optimal if…
You want GLP-1 therapy within a lab-driven functional-medicine program and a starting price around $99/mo.
Choose Näky if…
You want compounded oral semaglutide drops plus a microdose program and a starting price around $145/mo.
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MadeMed
Compounded GLP-1 in both injection and oral forms
From $219/mo
Get started →Found
Mainstream telehealth GLP-1 access
From $99/mo
Get started →Bodybuilding Health+
Fitness-brand compounded GLP-1 with hormone and performance programs
From $179/mo
Get started →1st Optimal vs Näky: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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