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1st Optimal vs Maximus

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
1st Optimal logo

1st Optimal

6.7
★★★☆☆3.4/5

Best for: GLP-1 therapy within a lab-driven functional-medicine program

Visit 1st Optimal
VS
Maximus logo

Maximus

7.6
★★★3.8/5

Best for: men seeking compounded GLP-1 alongside testosterone optimization

Visit Maximus

1st Optimal and Maximus are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 1st Optimal starts lower at $99/mo versus $249.99/mo, and Maximus edges ahead overall (7.6 vs 6.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

1st Optimal

Weight Loss Care membership — medication not includedBrand-name
$99/mo
semaglutide

Care membership only — the GLP-1 medication is billed separately and is not priced.

Maximus

1-Month plan, flat-rate across all dose tiersCompounded
$249.99/mo
semaglutide

1-month plan; the 4-month is $199.49/mo and the 12-month $150.32/mo.

1-Month plan, flat-rate across all dose tiersCompounded
$359.99/mo
tirzepatide

1-month plan; the 4-month is $298.99/mo and the 12-month $240.66/mo.

Starting atCompounded
$199.99/mo
orforglipron (foundayo)

Brand-name oral GLP-1; 'Foundayo starting at $199.99 /mo'

Starting atCompounded
$249.99/mo
semaglutide (wegovy)

Brand-name, dispensed as the manufacturer's pen or tablet.

Starting atCompounded
$349.99/mo
semaglutide (ozempic)

Brand-name, dispensed as the manufacturer's pen or tablet.

Starting atCompounded
$349.99/mo
semaglutide (wegovy)

Brand-name, dispensed as the manufacturer's pen or tablet.

Starting atCompounded
$449.99/mo
tirzepatide (zepbound)

Brand-name; multi-dose KwikPen at same self-pay price as vial

Starting atCompounded
$1249.99/mo
tirzepatide (mounjaro)

Brand-name; on-label tirzepatide

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What’s included

1st Optimal

What the monthly price covers

Medication

Not disclosed

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Included

Maximus

What the monthly price covers

Medication

Included

Provider visits

Not disclosed

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

1st Optimal

6.7/10

Overall

Maximus

7.6/10

Value25%

6.5A
vs
B
6.5

Effectiveness25%

7.0A
vs
B
8.5

User Experience15%

6.5A
vs
B
8.0

Trust & Safety15%

6.5A
vs
B
7.3

Accessibility10%

6.5A
vs
B
7.5

Support10%

7.4A
vs
B
8.0

Features & Coverage

Feature1st OptimalMaximus
Starting Price$99/mo$249.99/mo
Features8 features5 features
States AvailableNot disclosed51
Compounded✓ Yes
Brand Name✓ Yes
FSA/HSA Accepted
FDA WarningsNone1 warning

About 1st Optimal

1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets. Its model pairs prescription GLP-1 therapy with at-home lab testing, blood-work interpretation, unlimited coaching, and personalized protocols framed around long-term weight loss and longevity. Care is delivered virtually by credentialed providers, and treatments ship to the home with no long-term contracts. The site does not publish monthly pricing or a state list.

Read our full 1st Optimal review →

About Maximus

Maximus is a men's health platform offering compounded semaglutide (from $149.99/mo with a 12-month plan) and compounded tirzepatide alongside testosterone replacement therapy and longevity treatments. Available in all 50 states + DC. Microdose protocol available for patients with less weight to lose.

Read our full Maximus review →

Pros & Cons

1st Optimal

What we like

  • Offers both semaglutide and tirzepatide with injectable and oral formats
  • Functional-medicine approach with at-home labs and blood-work interpretation
  • Unlimited coaching and ongoing support included
  • No long-term contracts
  • Board-certified doctors and nurse practitioners referenced

Watch-outs

  • No public monthly pricing disclosed
  • No published state availability list
  • Compounded vs branded sourcing not clarified on site
  • Pricing only revealed after quiz or consultation

Maximus

What we like

  • All 50 states + DC coverage
  • Microdose GLP-1 protocol for patients with less weight to lose
  • Established men's health brand
  • Semaglutide from $149.99/mo and tirzepatide from $249.99/mo on 12-month plans, flat-rate across all dose tiers ($249.99/$359.99 month-to-month)

Watch-outs

  • No LegitScript or PCAB certification found
  • BBB F rating reported by third-party reviewers — complaints about unfulfilled prescriptions
  • Men's health platform — TRT is the core product, GLP-1 is secondary
  • Compounded only — no brand-name options

Our Verdict

Winner: Maximus

Maximus edges out 1st Optimal with a higher overall score of 7.6/10 and is particularly strong for men seeking compounded GLP-1 alongside testosterone optimization. 1st Optimal remains a solid alternative, especially if you're looking for GLP-1 therapy within a lab-driven functional-medicine program.

Choose 1st Optimal if…

You want GLP-1 therapy within a lab-driven functional-medicine program and a starting price around $99/mo.

Choose Maximus if…

You want men seeking compounded GLP-1 alongside testosterone optimization and a starting price around $249.99/mo.

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7.6

Maximus

Men seeking compounded GLP-1 alongside testosterone optimization

8.0

Sesame Care

Brand-name GLP-1s at cash prices, no compounding

6.9

Try Ageless

Lowest-tier compounded GLP-1 in injection, troche and sublingual forms

1st Optimal vs Maximus: FAQ

1st Optimal is cheaper. Its lowest ongoing monthly cash price is $99/mo, compared with $249.99/mo for Maximus. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.
Maximus scores higher overall at 7.6/10 versus 6.7/10, and is particularly strong for men seeking compounded GLP-1 alongside testosterone optimization. That said, 1st Optimal is a better fit if you want GLP-1 therapy within a lab-driven functional-medicine program.
Maximus lists availability in 51 states, while 1st Optimal's state list is not publicly listed.
Maximus is an affiliate partner (we may earn a commission on sign-ups through our links); 1st Optimal is not. Either way, we rank providers editorially with the same scoring framework and disclose every partnership — being a partner does not buy a higher score.
For Semaglutide, 1st Optimal is cheaper at $99/mo versus $249.99/mo at Maximus.

Key terms, explained

New to GLP-1s? Tap any term for a quick, plain-English definition.

Continue exploring 1st Optimal and Maximus head-to-heads in the same category.

Or see the full category ranking.

Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.