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1st Optimal vs JustAnswer Weight Loss

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
1st Optimal logo

1st Optimal

6.7
★★★☆☆3.4/5

Best for: Patients wanting GLP-1 therapy within a lab-driven functional-medicine program

Visit 1st Optimal
VS
JustAnswer Weight Loss logo

JustAnswer Weight Loss

7.0
★★★3.5/5

Best for: pending verification

Visit JustAnswer Weight Loss

1st Optimal and JustAnswer Weight Loss are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, JustAnswer Weight Loss starts at $149.97/mo, and JustAnswer Weight Loss edges ahead overall (7.0 vs 6.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

1st Optimal

Pricing not publicly listed.

JustAnswer Weight Loss

Flat — all dosage levelsCompounded
$149.97/mo
semaglutide

Monthly plan $149.97/mo; 6-month $130.00/mo; 12-month $112.49/mo. Semaglutide + B12. Free shipping, automatic refills.

Flat — all dosage levelsCompounded
$249.97/mo
tirzepatide

Monthly plan $249.97/mo; 6-month $220.00/mo; 12-month $195.82/mo. Tirzepatide + B12. Free shipping, automatic refills.

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What’s included

1st Optimal

Inclusions not disclosed.

JustAnswer Weight Loss

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

1st Optimal

6.7/10

Overall

JustAnswer Weight Loss

7.0/10

Value25%

6.5A
vs
B
7.0

Effectiveness25%

7.0A
vs
B
7.0

User Experience15%

6.5A
vs
B
7.0

Trust & Safety15%

6.5A
vs
B
7.3

Accessibility10%

6.5A
vs
B
7.0

Support10%

7.4A
vs
B
7.0

Features & Coverage

Feature1st OptimalJustAnswer Weight Loss
Starting Price$149.97/mo
Features8 features0 features
States AvailableNot disclosedNot disclosed
Compounded✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About 1st Optimal

1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets. Its model pairs prescription GLP-1 therapy with at-home lab testing, blood-work interpretation, unlimited coaching, and personalized protocols framed around long-term weight loss and longevity. Care is delivered virtually by credentialed providers, and treatments ship to the home with no long-term contracts. The site does not publish monthly pricing or a state list.

Read our full 1st Optimal review →

About JustAnswer Weight Loss

JustAnswer Weight Loss (weightloss.justanswer.com) — GLP-1 telehealth service. User-confirmed GLP-1 offering; JS-gated landing page was not scrapeable via WebFetch.

Read our full JustAnswer Weight Loss review →

Pros & Cons

1st Optimal

What we like

  • Offers both semaglutide and tirzepatide with injectable and oral formats
  • Functional-medicine approach with at-home labs and blood-work interpretation
  • Unlimited coaching and ongoing support included
  • No long-term contracts
  • Board-certified doctors and nurse practitioners referenced

Watch-outs

  • No public monthly pricing disclosed
  • No published state availability list
  • Compounded vs branded sourcing not clarified on site
  • Pricing only revealed after quiz or consultation

JustAnswer Weight Loss

Our Verdict

Winner: JustAnswer Weight Loss

JustAnswer Weight Loss edges out 1st Optimal with a higher overall score of 7.0/10 and is particularly strong for pending verification. 1st Optimal remains a solid alternative, especially if you're looking for Patients wanting GLP-1 therapy within a lab-driven functional-medicine program.

Choose 1st Optimal if…

You want Patients wanting GLP-1 therapy within a lab-driven functional-medicine program.

Choose JustAnswer Weight Loss if…

You want pending verification and a starting price around $149.97/mo.

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1st Optimal vs JustAnswer Weight Loss: FAQ

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