1st Optimal vs June Health
An in-depth comparison of two leading GLP-1 Providers
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1st Optimal
Best for: Patients wanting GLP-1 therapy within a lab-driven functional-medicine program
Visit 1st Optimal →
June Health
Best for: shoppers comparing published per-dose compounded GLP-1 pricing on a brand-new, unverified telehealth site
Visit June Health →1st Optimal and June Health are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, June Health starts at $179/mo, and both land at 6.7/10 overall. Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
1st Optimal
Pricing not publicly listed.
June Health
Semaglutide with (B12 or Glycine) injectable solution, lowest published tier of 5 dose tiers. Live-verified 2026-07-11
Semaglutide / Pyridoxine oral tablets, 1mg/10mg starting dose; 6 tiers rising to 24mg/10mg at $329/mo. Live-verified 2026-07-11
Tirzepatide with (B12 or Glycine) injectable solution, lowest published tier of 6 dose tiers. Live-verified 2026-07-11
Oral Tirzepatide Tablets, 3mg starting dose, 6 dose tiers published. Live-verified 2026-07-11
What’s included
1st Optimal
Inclusions not disclosed.
June Health
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
1st Optimal
6.7/10
June Health
6.7/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | 1st Optimal | June Health |
|---|---|---|
| Starting Price | — | $179/mo |
| Features | 8 features | 8 features |
| States Available | Not disclosed | Not disclosed |
| Compounded | — | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | ✓ Yes |
| FDA Warnings | None | None |
About 1st Optimal
1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets. Its model pairs prescription GLP-1 therapy with at-home lab testing, blood-work interpretation, unlimited coaching, and personalized protocols framed around long-term weight loss and longevity. Care is delivered virtually by credentialed providers, and treatments ship to the home with no long-term contracts. The site does not publish monthly pricing or a state list.
Read our full 1st Optimal review →About June Health
June Health is a direct-to-consumer telehealth storefront selling compounded GLP-1 medication for weight loss, alongside peptide, hormone, and hair-loss programs, all delivered online with no office visits. It publishes per-dose pricing for both injectable and oral compounded semaglutide and tirzepatide, starting from $179/mo, with the clinician evaluation bundled into that price. The site is new — its domain was registered in May 2026 — and has no working Terms of Service or Privacy Policy page, and no LegitScript or named-pharmacy disclosure.
Read our full June Health review →Pros & Cons
1st Optimal
What we like
- Offers both semaglutide and tirzepatide with injectable and oral formats
- Functional-medicine approach with at-home labs and blood-work interpretation
- Unlimited coaching and ongoing support included
- No long-term contracts
- Board-certified doctors and nurse practitioners referenced
Watch-outs
- No public monthly pricing disclosed
- No published state availability list
- Compounded vs branded sourcing not clarified on site
- Pricing only revealed after quiz or consultation
June Health
What we like
- Offers both injectable and oral compounded semaglutide and tirzepatide
- Semaglutide starts at $179/mo (injectable) or $187/mo (tablets) — tirzepatide from $179/mo (injectable)
- Full per-dose price list published on-site with no signup required to view it
- Provider consult ('licensed clinician evaluation') is bundled into the displayed price
- Free discreet shipping advertised with 2-3 day delivery
- HSA/FSA eligible, no long-term contract — cancel anytime through the portal or by messaging your care team
- Also sells peptide, hormone (TRT/HRT), hair-loss, and sexual-health programs from the same storefront
Watch-outs
- No accessible Terms of Service or Privacy Policy — footer links go nowhere and standard URL guesses 404
- No LegitScript seal or other pharmacy-verification badge found anywhere on the site
- Legal entity, prescribing medical group, and compounding pharmacy partner are not named
- Domain was registered in May 2026 — a brand-new storefront with no independent reviews found
- Also sells 'MR-3' (retatrutide), a GLP-1/GIP/glucagon agonist with no FDA approval for any use
- States-available list not published — site only claims 'licensed in all 50 states' without itemizing them
- No public support phone number or email found — only an on-site contact form
Our Verdict
Both 1st Optimal and June Health score equally well overall — the right choice depends on your priorities.
Choose 1st Optimal if…
You want Patients wanting GLP-1 therapy within a lab-driven functional-medicine program.
Choose June Health if…
You want shoppers comparing published per-dose compounded GLP-1 pricing on a brand-new, unverified telehealth site and a starting price around $179/mo.
Ready to start? Vetted GLP-1 providers
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Embody
Lowest first-month entry pricing on compounded GLP-1s
From $79/mo
Get started →ShedRx
Mainstream telehealth GLP-1 access
From $199/mo
Get started →DudeMeds
Men seeking no-fee GLP-1 access with oral and injectable options
From $149/mo
Get started →1st Optimal vs June Health: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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