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1st Optimal vs Idgie Health

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
1st Optimal logo

1st Optimal

6.7
★★★☆☆3.4/5

Best for: GLP-1 therapy within a lab-driven functional-medicine program

Visit 1st Optimal
VS
Idgie Health logo

Idgie Health

7.7
★★★3.9/5

Best for: month-to-month compounded GLP-1s at one price for every dose, with the pharmacy named

Visit Idgie Health

1st Optimal and Idgie Health are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 1st Optimal starts lower at $99/mo versus $134/mo, and Idgie Health edges ahead overall (7.7 vs 6.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

1st Optimal

Weight Loss Care membership — medication not includedBrand-name
$99/mo
semaglutide

Care membership only — the GLP-1 medication is billed separately and is not priced.

Idgie Health

Once-weekly compounded injection, billed monthly (same price at every dose)Compounded
$149/mo
semaglutide

'1 Month · Billed monthly · all doses · $149/mo'. Prepaid plans: $387 charged today for 3 months ($129/mo), or $687 for 6 months (shown as $114/mo).

Once-weekly compounded injection, billed monthly (same price at every dose)Compounded
$229/mo
tirzepatide

'1 Month · Billed monthly, flexible · $229/mo'. Prepaid plans: $557 charged today for 3 months (shown as $185/mo), or $1,029 for 6 months (shown as $171/mo).

Microdose weekly injection (below the standard starting dose), billed monthlyCompounded
$134/mo
semaglutide

'Semaglutide Compounded Microdose', '1 Month · Billed monthly, flexible · $134/mo'; or $377 charged today for 3 months (shown as $125/mo). The site calls microdosing an off-label approach.

Microdose weekly injection (below the standard starting dose), billed monthlyCompounded
$179/mo
tirzepatide

'Tirzepatide Microdose', '1 Month · Billed monthly, flexible · $179/mo'; or $497 charged today for 3 months (shown as $165/mo).

Oral ODT (dissolving tablet) with ondansetron, billed monthlyCompounded
$287/mo
semaglutide

'Semaglutide ODT Tablets', '1 Month · Billed monthly, flexible · $287/mo'; or $747 charged today for 3 months ($249/mo). The program menu names it 'Semaglutide/Ondansetron ODT'.

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What’s included

1st Optimal

What the monthly price covers

Medication

Not disclosed

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Included

Idgie Health

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

1st Optimal

6.7/10

Overall

Idgie Health

7.7/10

Value25%

6.5A
vs
B
8.2

Effectiveness25%

7.0A
vs
B
8.0

User Experience15%

6.5A
vs
B
7.2

Trust & Safety15%

6.5A
vs
B
7.2

Accessibility10%

6.5A
vs
B
7.8

Support10%

7.4A
vs
B
7.0

Features & Coverage

Feature1st OptimalIdgie Health
Starting Price$99/mo$134/mo
Features8 features8 features
States AvailableNot disclosed50
Compounded✓ Yes
Brand Name✓ Yes
FSA/HSA Accepted
FDA WarningsNoneNone

About 1st Optimal

1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets. Its model pairs prescription GLP-1 therapy with at-home lab testing, blood-work interpretation, unlimited coaching, and personalized protocols framed around long-term weight loss and longevity. Care is delivered virtually by credentialed providers, and treatments ship to the home with no long-term contracts. The site does not publish monthly pricing or a state list.

Read our full 1st Optimal review →

About Idgie Health

Idgie Health is an online weight-management clinic selling compounded semaglutide and tirzepatide as weekly injections, lower-dose microdose plans and dissolving tablets. Month to month, semaglutide is $149 and tirzepatide $229, the same price at every dose, and prepaid three- and six-month plans lower the monthly rate. It names its prescribing medical group and its dispensing pharmacy, and also sells NAD+, glutathione, sermorelin and hair and skin treatments.

Read our full Idgie Health review →

Pros & Cons

1st Optimal

What we like

  • Offers both semaglutide and tirzepatide with injectable and oral formats
  • Functional-medicine approach with at-home labs and blood-work interpretation
  • Unlimited coaching and ongoing support included
  • No long-term contracts
  • Board-certified doctors and nurse practitioners referenced

Watch-outs

  • No public monthly pricing disclosed
  • No published state availability list
  • Compounded vs branded sourcing not clarified on site
  • Pricing only revealed after quiz or consultation

Idgie Health

What we like

  • Month-to-month prices are public before you start: semaglutide $149/mo, tirzepatide $229/mo
  • One price at every dose, stated outright: 'Your price never moves' as your dose rises, with a $0 dose surcharge
  • Names its prescribing group (Arora Health & Aesthetics, Seattle) and its dispensing pharmacy (VialsRx, Houston)
  • The plan price covers the provider evaluation, medication, injection supplies, unlimited provider messaging and shipping
  • No membership fee, no consultation fee and no insurance needed
  • Prepaid three- and six-month plans lower the rate, and each shows the full amount charged up front
  • Microdose and needle-free dissolving-tablet options sit alongside standard weekly injections
  • LegitScript seal is served from LegitScript's own image server, not self-hosted

Watch-outs

  • The headline 'from $114' is the six-month prepay rate ($687 up front); the $149 monthly price is behind a collapsed menu
  • You must create an account with a password before you see a single medical question
  • All sales are final: prescription products cannot be returned, and only a pharmacy filling error is carved out
  • The Terms of Service are written for a testosterone program and never mention weight-loss treatment
  • Shipping claims conflict: 'free 2-day shipping' on product pages, but the shipping policy says 4 to 12 business days
  • Two different support phone numbers are published, one in the policies and another on the intake page
  • Compounded semaglutide and tirzepatide are not FDA-approved

Our Verdict

Winner: Idgie Health

Idgie Health edges out 1st Optimal with a higher overall score of 7.7/10 and is particularly strong for month-to-month compounded GLP-1s at one price for every dose, with the pharmacy named. 1st Optimal remains a solid alternative, especially if you're looking for GLP-1 therapy within a lab-driven functional-medicine program.

Choose 1st Optimal if…

You want GLP-1 therapy within a lab-driven functional-medicine program and a starting price around $99/mo.

Choose Idgie Health if…

You want month-to-month compounded GLP-1s at one price for every dose, with the pharmacy named and a starting price around $134/mo.

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1st Optimal vs Idgie Health: FAQ

1st Optimal is cheaper. Its lowest ongoing monthly cash price is $99/mo, compared with $134/mo for Idgie Health. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.
Idgie Health scores higher overall at 7.7/10 versus 6.7/10, and is particularly strong for month-to-month compounded GLP-1s at one price for every dose, with the pharmacy named. That said, 1st Optimal is a better fit if you want GLP-1 therapy within a lab-driven functional-medicine program.
Idgie Health lists availability in 50 states, while 1st Optimal's state list is not publicly listed.
Neither 1st Optimal nor Idgie Health is currently an affiliate partner, so we earn no commission from either. We rank all providers editorially using the same six-dimension framework and disclose any commercial relationships.
For Semaglutide, 1st Optimal is cheaper at $99/mo versus $134/mo at Idgie Health.

Key terms, explained

New to GLP-1s? Tap any term for a quick, plain-English definition.

Continue exploring 1st Optimal and Idgie Health head-to-heads in the same category.

Or see the full category ranking.

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