Always verify pricing and state availability on the provider's website before signing up.How our reviews work →

1st Optimal vs Heally

An in-depth comparison of two leading GLP-1 Providers

WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more

By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
1st Optimal logo

1st Optimal

6.7
★★★☆☆3.4/5

Best for: GLP-1 therapy within a lab-driven functional-medicine program

Visit 1st Optimal
VS
Heally logo

Heally

7.3
★★★3.7/5

Best for: A wide GLP-1 menu, branded or compounded, LegitScript-verified

Visit Heally

1st Optimal and Heally are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 1st Optimal starts lower at $99/mo versus $199/mo, and Heally edges ahead overall (7.3 vs 6.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

1st Optimal

Weight Loss Care membership — medication not includedBrand-name
$99/mo
semaglutide

Care membership only — the GLP-1 medication is billed separately and is not priced.

Heally

startingCompounded
$199/mo
semaglutide
starting (LillyDirect)Brand-name
$299/mo
tirzepatide

Get alerted when GLP-1 prices drop

Join the GLP-1 price-watch list — we re-verify 500+ providers' prices on their own sites and email you when tracked prices move.

What’s included

1st Optimal

What the monthly price covers

Medication

Not disclosed

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Included

Heally

Inclusions not disclosed.

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

1st Optimal

6.7/10

Overall

Heally

7.3/10

Value25%

6.5A
vs
B
7.0

Effectiveness25%

7.0A
vs
B
7.5

User Experience15%

6.5A
vs
B
7.0

Trust & Safety15%

6.5A
vs
B
7.3

Accessibility10%

6.5A
vs
B
7.5

Support10%

7.4A
vs
B
7.4

Features & Coverage

Feature1st OptimalHeally
Starting Price$99/mo$199/mo
Features8 features8 features
States AvailableNot disclosed50
Compounded✓ Yes
Brand Name✓ Yes✓ Yes
FSA/HSA Accepted
FDA WarningsNoneNone

About 1st Optimal

1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets. Its model pairs prescription GLP-1 therapy with at-home lab testing, blood-work interpretation, unlimited coaching, and personalized protocols framed around long-term weight loss and longevity. Care is delivered virtually by credentialed providers, and treatments ship to the home with no long-term contracts. The site does not publish monthly pricing or a state list.

Read our full 1st Optimal review →

About Heally

Heally is a US telehealth platform connecting patients with licensed providers for GLP-1 weight loss prescriptions; care is by HLY Medical Group PA. Providers may prescribe FDA-approved branded drugs (semaglutide as Ozempic/Wegovy/Rybelsus, tirzepatide as Mounjaro/Zepbound, plus liraglutide) or compounded alternatives per medical need. Semaglutide programs start near $199/mo and Zepbound via LillyDirect from $299/mo, with a $100-off first month. Meds ship from licensed pharmacies with free shipping. LegitScript verified, 100% online, in almost every state (excluding Alaska and DC).

Read our full Heally review →

Pros & Cons

1st Optimal

What we like

  • Offers both semaglutide and tirzepatide with injectable and oral formats
  • Functional-medicine approach with at-home labs and blood-work interpretation
  • Unlimited coaching and ongoing support included
  • No long-term contracts
  • Board-certified doctors and nurse practitioners referenced

Watch-outs

  • No public monthly pricing disclosed
  • No published state availability list
  • Compounded vs branded sourcing not clarified on site
  • Pricing only revealed after quiz or consultation

Heally

What we like

  • Broad GLP-1 menu: semaglutide, tirzepatide and liraglutide (branded or compounded)
  • LegitScript verified; care provided by HLY Medical Group PA
  • Semaglutide from ~$199/mo with a $100-off first-month promotion
  • Medications ship from licensed, state-regulated pharmacies with free shipping
  • Available in almost every state (excluding Alaska and DC)

Watch-outs

  • Compounded medications are not FDA-evaluated for safety, efficacy or quality
  • Cash-pay; FSA/HSA acceptance not stated on the platform
  • Some pricing routes through LillyDirect rather than Heally directly
  • Specific list of supported states not consolidated for easy review

Our Verdict

Winner: Heally

Heally edges out 1st Optimal with a higher overall score of 7.3/10 and is particularly strong for A wide GLP-1 menu, branded or compounded, LegitScript-verified. 1st Optimal remains a solid alternative, especially if you're looking for GLP-1 therapy within a lab-driven functional-medicine program.

Choose 1st Optimal if…

You want GLP-1 therapy within a lab-driven functional-medicine program and a starting price around $99/mo.

Choose Heally if…

You want A wide GLP-1 menu, branded or compounded, LegitScript-verified and a starting price around $199/mo.

Ready to start? Vetted GLP-1 providers

Vetted telehealth providers that prescribe GLP-1 online.

No insurance needed · vetted by our editors

WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more

8.3

Found

Mainstream telehealth GLP-1 access

7.4

Breeze Meds

Compounded GLP-1 access with named prescribers and 4-pharmacy network

7.4

Telos Rx

Needle-free, microdosed compounded GLP-1 with lab-monitored care

1st Optimal vs Heally: FAQ

1st Optimal is cheaper. Its lowest ongoing monthly cash price is $99/mo, compared with $199/mo for Heally. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.
Heally scores higher overall at 7.3/10 versus 6.7/10, and is particularly strong for A wide GLP-1 menu, branded or compounded, LegitScript-verified. That said, 1st Optimal is a better fit if you want GLP-1 therapy within a lab-driven functional-medicine program.
Heally lists availability in 50 states, while 1st Optimal's state list is not publicly listed.
Neither 1st Optimal nor Heally is currently an affiliate partner, so we earn no commission from either. We rank all providers editorially using the same six-dimension framework and disclose any commercial relationships.
For Semaglutide, 1st Optimal is cheaper at $99/mo versus $199/mo at Heally.

Key terms, explained

New to GLP-1s? Tap any term for a quick, plain-English definition.

Continue exploring 1st Optimal and Heally head-to-heads in the same category.

Or see the full category ranking.

Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.