1st Optimal vs Heally
An in-depth comparison of two leading GLP-1 Providers
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1st Optimal
Best for: Patients wanting GLP-1 therapy within a lab-driven functional-medicine program
Visit 1st Optimal →
Heally
Best for: Patients wanting a wide GLP-1 menu (branded or compounded) from a LegitScript-verified platform.
Visit Heally →1st Optimal and Heally are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Heally starts at $199/mo, and Heally edges ahead overall (7.3 vs 6.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
1st Optimal
Pricing not publicly listed.
Heally
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Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
1st Optimal
6.7/10
Heally
7.3/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | 1st Optimal | Heally |
|---|---|---|
| Starting Price | — | $199/mo |
| Features | 8 features | 8 features |
| States Available | Not disclosed | 50 |
| Compounded | — | ✓ Yes |
| Brand Name | — | ✓ Yes |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About 1st Optimal
1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets. Its model pairs prescription GLP-1 therapy with at-home lab testing, blood-work interpretation, unlimited coaching, and personalized protocols framed around long-term weight loss and longevity. Care is delivered virtually by credentialed providers, and treatments ship to the home with no long-term contracts. The site does not publish monthly pricing or a state list.
Read our full 1st Optimal review →About Heally
Heally is a US telehealth platform connecting patients with licensed providers for GLP-1 weight loss prescriptions; care is by HLY Medical Group PA. Providers may prescribe FDA-approved branded drugs (semaglutide as Ozempic/Wegovy/Rybelsus, tirzepatide as Mounjaro/Zepbound, plus liraglutide) or compounded alternatives per medical need. Semaglutide programs start near $199/mo and Zepbound via LillyDirect from $299/mo, with a $100-off first month. Meds ship from licensed pharmacies with free shipping. LegitScript verified, 100% online, in almost every state (excluding Alaska and DC).
Read our full Heally review →Pros & Cons
1st Optimal
What we like
- Offers both semaglutide and tirzepatide with injectable and oral formats
- Functional-medicine approach with at-home labs and blood-work interpretation
- Unlimited coaching and ongoing support included
- No long-term contracts
- Board-certified doctors and nurse practitioners referenced
Watch-outs
- No public monthly pricing disclosed
- No published state availability list
- Compounded vs branded sourcing not clarified on site
- Pricing only revealed after quiz or consultation
Heally
What we like
- Broad GLP-1 menu: semaglutide, tirzepatide and liraglutide (branded or compounded)
- LegitScript verified; care provided by HLY Medical Group PA
- Semaglutide from ~$199/mo with a $100-off first-month promotion
- Medications ship from licensed, state-regulated pharmacies with free shipping
- Available in almost every state (excluding Alaska and DC)
Watch-outs
- Compounded medications are not FDA-evaluated for safety, efficacy or quality
- Cash-pay; FSA/HSA acceptance not stated on the platform
- Some pricing routes through LillyDirect rather than Heally directly
- Specific list of supported states not consolidated for easy review
Our Verdict
Heally edges out 1st Optimal with a higher overall score of 7.3/10 and is particularly strong for Patients wanting a wide GLP-1 menu (branded or compounded) from a LegitScript-verified platform.. 1st Optimal remains a solid alternative, especially if you're looking for Patients wanting GLP-1 therapy within a lab-driven functional-medicine program.
Choose 1st Optimal if…
You want Patients wanting GLP-1 therapy within a lab-driven functional-medicine program.
Choose Heally if…
You want Patients wanting a wide GLP-1 menu (branded or compounded) from a LegitScript-verified platform. and a starting price around $199/mo.
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Found
Mainstream telehealth GLP-1 access
From $99/mo
Get started →Breeze Meds
Compounded GLP-1 access with named prescribers and 4-pharmacy network
From $169/mo
Get started →Telos Rx
Needle-free and microdosed compounded GLP-1 options with lab-monitored care
From $49/mo
Get started →1st Optimal vs Heally: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.