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1st Optimal vs Gimme Care

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
1st Optimal logo

1st Optimal

6.7
★★★☆☆3.4/5

Best for: GLP-1 therapy within a lab-driven functional-medicine program

Visit 1st Optimal
VS
Gimme Care logo

Gimme Care

7.8
★★★3.9/5

Best for: affordable compounded GLP-1 with nationwide coverage and microdose options

Visit Gimme Care

1st Optimal and Gimme Care are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 1st Optimal starts lower at $99/mo versus $130/mo, and Gimme Care edges ahead overall (7.8 vs 6.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

1st Optimal

Weight Loss Care membership — medication not includedBrand-name
$99/mo
semaglutide

Care membership only — the GLP-1 medication is billed separately and is not priced.

Gimme Care

Compounded Semaglutide (3-mo)Compounded
$130/mo
semaglutide
Compounded Semaglutide (1-mo)Compounded
$160/mo
semaglutide
Compounded Tirzepatide (3-mo)Compounded
$163/mo
tirzepatide
Compounded Tirzepatide (1-mo)Compounded
$199/mo
tirzepatide

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What’s included

1st Optimal

What the monthly price covers

Medication

Not disclosed

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Included

Gimme Care

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

1st Optimal

6.7/10

Overall

Gimme Care

7.8/10

Value25%

6.5A
vs
B
8.0

Effectiveness25%

7.0A
vs
B
7.5

User Experience15%

6.5A
vs
B
7.5

Trust & Safety15%

6.5A
vs
B
7.8

Accessibility10%

6.5A
vs
B
9.0

Support10%

7.4A
vs
B
7.0

Features & Coverage

Feature1st OptimalGimme Care
Starting Price$99/mo$130/mo
Features8 features5 features
States AvailableNot disclosed51
Compounded✓ Yes
Brand Name✓ Yes
FSA/HSA Accepted
FDA WarningsNoneNone

About 1st Optimal

1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets. Its model pairs prescription GLP-1 therapy with at-home lab testing, blood-work interpretation, unlimited coaching, and personalized protocols framed around long-term weight loss and longevity. Care is delivered virtually by credentialed providers, and treatments ship to the home with no long-term contracts. The site does not publish monthly pricing or a state list.

Read our full 1st Optimal review →

About Gimme Care

Gimme Care offers compounded semaglutide ($130–$160/mo) and compounded tirzepatide ($163–$199/mo) including microdose options. LegitScript verified. Available in all 50 states + DC. No membership fees.

Read our full Gimme Care review →

Pros & Cons

1st Optimal

What we like

  • Offers both semaglutide and tirzepatide with injectable and oral formats
  • Functional-medicine approach with at-home labs and blood-work interpretation
  • Unlimited coaching and ongoing support included
  • No long-term contracts
  • Board-certified doctors and nurse practitioners referenced

Watch-outs

  • No public monthly pricing disclosed
  • No published state availability list
  • Compounded vs branded sourcing not clarified on site
  • Pricing only revealed after quiz or consultation

Gimme Care

What we like

  • All 50 states + DC coverage — broadest availability in the dataset
  • LegitScript verified
  • Both semaglutide and tirzepatide in compounded formats
  • Microdose options available for both drugs
  • No membership fees — price includes medication, physician, support, shipping, and supplies
  • Multi-month discount: semaglutide $130/mo on 3-month plan

Watch-outs

  • Five states require video/audio visits (KS, LA, MS, NM, WV)
  • Compounded only — no brand-name options
  • Also offers anti-aging treatments (NAD+, Sermorelin, Glutathione)

Our Verdict

Winner: Gimme Care

Gimme Care edges out 1st Optimal with a higher overall score of 7.8/10 and is particularly strong for affordable compounded GLP-1 with nationwide coverage and microdose options. 1st Optimal remains a solid alternative, especially if you're looking for GLP-1 therapy within a lab-driven functional-medicine program.

Choose 1st Optimal if…

You want GLP-1 therapy within a lab-driven functional-medicine program and a starting price around $99/mo.

Choose Gimme Care if…

You want affordable compounded GLP-1 with nationwide coverage and microdose options and a starting price around $130/mo.

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7.4

MadeMed

Compounded GLP-1 in both injection and oral forms

8.3

Found

Mainstream telehealth GLP-1 access

7.1

Bodybuilding Health+

Fitness-brand compounded GLP-1 with hormone and performance programs

1st Optimal vs Gimme Care: FAQ

1st Optimal is cheaper. Its lowest ongoing monthly cash price is $99/mo, compared with $130/mo for Gimme Care. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.
Gimme Care scores higher overall at 7.8/10 versus 6.7/10, and is particularly strong for affordable compounded GLP-1 with nationwide coverage and microdose options. That said, 1st Optimal is a better fit if you want GLP-1 therapy within a lab-driven functional-medicine program.
Gimme Care lists availability in 51 states, while 1st Optimal's state list is not publicly listed.
Neither 1st Optimal nor Gimme Care is currently an affiliate partner, so we earn no commission from either. We rank all providers editorially using the same six-dimension framework and disclose any commercial relationships.
For Semaglutide, 1st Optimal is cheaper at $99/mo versus $130/mo at Gimme Care.

Key terms, explained

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Continue exploring 1st Optimal and Gimme Care head-to-heads in the same category.

Or see the full category ranking.

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