1st Optimal vs Get Thin MD
An in-depth comparison of two leading GLP-1 Providers
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1st Optimal
Best for Patients wanting GLP-1 therapy within a lab-driven functional-medicine programGet Thin MD
Best for lowest-priced compounded semaglutide on a 3-month commitment, with brand-name Ozempic/Zepbound also availableStarting at $169/mo
Side-by-Side Comparison
| Feature | 1st Optimal | Get Thin MD |
|---|---|---|
| Overall Score | 6.7/10 | ✓7.9/10 |
| Starting Price | — | $169/mo |
| Editorial Rating | 3.4 ★ /5 | ✓4 ★ /5 |
| Features | ✓8 features | 7 features |
| States Available | 0 | 0 |
| Compounded | — | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
Pros & Cons
1st Optimal
Pros
- ✓Offers both semaglutide and tirzepatide with injectable and oral formats
- ✓Functional-medicine approach with at-home labs and blood-work interpretation
- ✓Unlimited coaching and ongoing support included
- ✓No long-term contracts
- ✓Board-certified doctors and nurse practitioners referenced
Cons
- ✗No public monthly pricing disclosed
- ✗No published state availability list
- ✗Compounded vs branded sourcing not clarified on site
- ✗Pricing only revealed after quiz or consultation
Get Thin MD
Pros
- ✓3-month compounded semaglutide at $169/mo is among the lowest ongoing prices in the category
- ✓Price-lock promise — same price every dose, no hidden fees
- ✓Both compounded and brand-name options on one platform (sema, tirz, plus Ozempic and Zepbound)
- ✓Nationwide availability with async evaluation — no in-person visit
- ✓Broader wellness menu (sermorelin, NAD+, HRT, hair loss) lets you consolidate protocols
- ✓Publishes the FDA compounded-medication disclaimer
Cons
- ✗Compounded medications aren't FDA-approved and lack the review of brand-name GLP-1s
- ✗Pharmacy partners not named — no way to verify the compounding source or batch testing
- ✗Claims nationwide coverage but publishes no state list — confirm at intake
- ✗Headline results (9.6 lbs in 30 days) come from self-reported patient data, not a trial
- ✗Wide wellness funnel may steer you toward non-weight-loss protocols
Our Verdict
Get Thin MD edges out 1st Optimal with a higher overall score of 7.9/10 and is particularly strong for lowest-priced compounded semaglutide on a 3-month commitment, with brand-name Ozempic/Zepbound also available. 1st Optimal remains a solid alternative, especially if you're looking for Patients wanting GLP-1 therapy within a lab-driven functional-medicine program.
Glossary references
Key terms in this article, linked to their canonical definitions.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
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