1st Optimal vs Gaya Wellness
An in-depth comparison of two leading GLP-1 Providers
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1st Optimal
Best for: Patients wanting GLP-1 therapy within a lab-driven functional-medicine program
Visit 1st Optimal →
Gaya Wellness
Best for: Women 40+ wanting GLP-1 weight loss integrated with menopause and hormone care
Visit Gaya Wellness →1st Optimal and Gaya Wellness are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Gaya Wellness starts at $349/mo, and Gaya Wellness edges ahead overall (6.9 vs 6.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
1st Optimal
Pricing not publicly listed.
Gaya Wellness
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What’s included
1st Optimal
Inclusions not disclosed.
Gaya Wellness
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Not disclosed
Lab work
Included
Coaching
Included
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
1st Optimal
6.7/10
Gaya Wellness
6.9/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | 1st Optimal | Gaya Wellness |
|---|---|---|
| Starting Price | — | $349/mo |
| Features | 8 features | 8 features |
| States Available | Not disclosed | 5 |
| Compounded | — | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | ✓ Yes |
| FDA Warnings | None | None |
About 1st Optimal
1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets. Its model pairs prescription GLP-1 therapy with at-home lab testing, blood-work interpretation, unlimited coaching, and personalized protocols framed around long-term weight loss and longevity. Care is delivered virtually by credentialed providers, and treatments ship to the home with no long-term contracts. The site does not publish monthly pricing or a state list.
Read our full 1st Optimal review →About Gaya Wellness
Gaya Wellness is a virtual, OB/GYN-led telehealth practice focused on women 40+ for menopause, hormone replacement, and weight loss. Its GLP-1 weight loss concierge prescribes compounded semaglutide or tirzepatide via board-certified physicians, with a 50+ biomarker lab panel, weekly asynchronous check-ins, and HSA/FSA-eligible payment. Tiers run from $149/mo for GLP-1 access (no medication) to $349/mo with compounded medication and $549/mo bundling GLP-1 with HRT. Eligibility is BMI 30+ (or 27+ with a metabolic condition), ages 18-64. Licensed in FL, NC, VA, IN, and TN.
Read our full Gaya Wellness review →Pros & Cons
1st Optimal
What we like
- Offers both semaglutide and tirzepatide with injectable and oral formats
- Functional-medicine approach with at-home labs and blood-work interpretation
- Unlimited coaching and ongoing support included
- No long-term contracts
- Board-certified doctors and nurse practitioners referenced
Watch-outs
- No public monthly pricing disclosed
- No published state availability list
- Compounded vs branded sourcing not clarified on site
- Pricing only revealed after quiz or consultation
Gaya Wellness
What we like
- OB/GYN-led care designed for women 40+ and menopause overlap
- Includes a 50+ biomarker lab panel and weekly physician check-ins
- HSA/FSA eligible with a GLP-1 plus bioidentical HRT bundle option
- Transparent tiered pricing published online
Watch-outs
- Weight loss is one vertical alongside menopause and hormone care
- Medication-included tiers ($349+/mo) are pricier than many compounders
- Available in only five states (FL, NC, VA, IN, TN)
Our Verdict
Gaya Wellness edges out 1st Optimal with a higher overall score of 6.9/10 and is particularly strong for Women 40+ wanting GLP-1 weight loss integrated with menopause and hormone care. 1st Optimal remains a solid alternative, especially if you're looking for Patients wanting GLP-1 therapy within a lab-driven functional-medicine program.
Choose 1st Optimal if…
You want Patients wanting GLP-1 therapy within a lab-driven functional-medicine program.
Choose Gaya Wellness if…
You want Women 40+ wanting GLP-1 weight loss integrated with menopause and hormone care and a starting price around $349/mo.
Ready to start? Vetted GLP-1 providers
Vetted telehealth providers that prescribe GLP-1 online.
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MadeMed
Compounded GLP-1 in both injection and oral forms
From $219/mo
Get started →Found
Mainstream telehealth GLP-1 access
From $99/mo
Get started →Breeze Meds
Compounded GLP-1 access with named prescribers and 4-pharmacy network
From $169/mo
Get started →1st Optimal vs Gaya Wellness: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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