1st Optimal vs Fidelity Medical Clinic
An in-depth comparison of two leading GLP-1 Providers
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1st Optimal
Best for: GLP-1 therapy within a lab-driven functional-medicine program
Visit 1st Optimal →
Fidelity Medical Clinic
Best for: Low-cost compounded GLP-1 from a clinic-plus-telehealth hybrid
Visit Fidelity Medical Clinic →1st Optimal and Fidelity Medical Clinic are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 1st Optimal starts lower at $99/mo versus $215.75/mo, and Fidelity Medical Clinic edges ahead overall (6.8 vs 6.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
1st Optimal
Care membership only — the GLP-1 medication is billed separately and is not priced.
Fidelity Medical Clinic
Maintenance is '$199 — Semaglutide and supplies for 4 doses (4 weeks)', which is 13 fills a year, or $215.75 a calendar month. The intro is '$99 — Initial Prescription — 2 month order required — supplies for 8 doses (2 months)', i.e. $49.50 a month for the first two.
ADDED 2026-08-15 — we had no tirzepatide row. Maintenance is '$349 — Tirzepatide Vial and supplies for 4 doses (4 weeks)' = $378.25 a calendar month. The intro, '$349 for a 2-Month Supply — 8 doses', works out at $174.50 a month for the first two.
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What’s included
1st Optimal
What the monthly price covers
Medication
Not disclosed
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Included
Fidelity Medical Clinic
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
1st Optimal
6.7/10
Fidelity Medical Clinic
6.8/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | 1st Optimal | Fidelity Medical Clinic |
|---|---|---|
| Starting Price | ✓$99/mo | $215.75/mo |
| Features | ✓8 features | 6 features |
| States Available | Not disclosed | 50 |
| Compounded | — | ✓ Yes |
| Brand Name | ✓ Yes | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About 1st Optimal
1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets. Its model pairs prescription GLP-1 therapy with at-home lab testing, blood-work interpretation, unlimited coaching, and personalized protocols framed around long-term weight loss and longevity. Care is delivered virtually by credentialed providers, and treatments ship to the home with no long-term contracts. The site does not publish monthly pricing or a state list.
Read our full 1st Optimal review →About Fidelity Medical Clinic
Fidelity Medical Clinic is a Tampa, Florida practice that also offers nationwide GLP-1 weight-loss telehealth: compounded semaglutide and tirzepatide, injectable or oral, with a free consultation and shipping included. Its prices are quoted per BATCH OF DOSES rather than per month — $99 buys eight semaglutide doses (two months) to start and $199 buys four thereafter, while tirzepatide is $349 for eight doses and then $349 for four.
Read our full Fidelity Medical Clinic review →Pros & Cons
1st Optimal
What we like
- Offers both semaglutide and tirzepatide with injectable and oral formats
- Functional-medicine approach with at-home labs and blood-work interpretation
- Unlimited coaching and ongoing support included
- No long-term contracts
- Board-certified doctors and nurse practitioners referenced
Watch-outs
- No public monthly pricing disclosed
- No published state availability list
- Compounded vs branded sourcing not clarified on site
- Pricing only revealed after quiz or consultation
Fidelity Medical Clinic
What we like
- Low-cost compounded semaglutide and tirzepatide from $99/month
- Injectable or oral options with a free telehealth consultation
- Ships nationally; clinic-plus-telehealth hybrid
Watch-outs
- Compounded GLP-1s are not FDA-approved finished products
- Local Tampa clinic with national telehealth — experience may vary
- Public state list is not enumerated
- Cash-pay model
Our Verdict
Fidelity Medical Clinic edges out 1st Optimal with a higher overall score of 6.8/10 and is particularly strong for Low-cost compounded GLP-1 from a clinic-plus-telehealth hybrid. 1st Optimal remains a solid alternative, especially if you're looking for GLP-1 therapy within a lab-driven functional-medicine program.
Choose 1st Optimal if…
You want GLP-1 therapy within a lab-driven functional-medicine program and a starting price around $99/mo.
Choose Fidelity Medical Clinic if…
You want Low-cost compounded GLP-1 from a clinic-plus-telehealth hybrid and a starting price around $215.75/mo.
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Budget-conscious shoppers
From $99/mo
Get started →1st Optimal vs Fidelity Medical Clinic: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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