1st Optimal vs Factor Health MD
An in-depth comparison of two leading GLP-1 Providers
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1st Optimal
Best for: GLP-1 therapy within a lab-driven functional-medicine program
Visit 1st Optimal →
Factor Health MD
Best for: broadest GLP-1 lineup — semaglutide, tirzepatide and liraglutide
Visit Factor Health MD →1st Optimal and Factor Health MD are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, both start around $99/mo, and 1st Optimal edges ahead overall (6.7 vs 6.4 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
1st Optimal
Care membership only — the GLP-1 medication is billed separately and is not priced.
Factor Health MD
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What’s included
1st Optimal
What the monthly price covers
Medication
Not disclosed
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Included
Factor Health MD
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
1st Optimal
6.7/10
Factor Health MD
6.4/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | 1st Optimal | Factor Health MD |
|---|---|---|
| Starting Price | $99/mo | $99/mo |
| Features | 8 features | 8 features |
| States Available | Not disclosed | Not disclosed |
| Compounded | — | ✓ Yes |
| Brand Name | ✓ Yes | — |
| FSA/HSA Accepted | — | ✓ Yes |
| FDA Warnings | None | None |
About 1st Optimal
1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets. Its model pairs prescription GLP-1 therapy with at-home lab testing, blood-work interpretation, unlimited coaching, and personalized protocols framed around long-term weight loss and longevity. Care is delivered virtually by credentialed providers, and treatments ship to the home with no long-term contracts. The site does not publish monthly pricing or a state list.
Read our full 1st Optimal review →About Factor Health MD
Factor Health MD is a Florida-based multi-vertical telehealth platform with an unusually broad GLP-1 lineup — compounded semaglutide, tirzepatide, and the rarely offered liraglutide — plus longevity, vitamin injectables, and men's health products. Its standout is that three-molecule menu with an "all doses included" promise and no per-dose price escalation. GLP-1 therapy starts at $99/mo; HSA/FSA cards accepted.
Read our full Factor Health MD review →Pros & Cons
1st Optimal
What we like
- Offers both semaglutide and tirzepatide with injectable and oral formats
- Functional-medicine approach with at-home labs and blood-work interpretation
- Unlimited coaching and ongoing support included
- No long-term contracts
- Board-certified doctors and nurse practitioners referenced
Watch-outs
- No public monthly pricing disclosed
- No published state availability list
- Compounded vs branded sourcing not clarified on site
- Pricing only revealed after quiz or consultation
Factor Health MD
What we like
- Three-GLP-1 lineup including liraglutide — rare in DTC and useful for patients sensitive to newer molecules
- Aggressive $99/mo starting tier with all doses included
- Multi-product platform (GLP-1, longevity, vitamin injectables, men's health, bundles)
- HSA/FSA accepted — uncommon for compounded GLP-1
- St. Petersburg, FL location and phone (305-930-8817) for accountability
- LegitScript verification badge displayed
- Free medical consultations
- Price doesn't increase per dose as patients titrate up
Watch-outs
- 503A/503B pharmacy partner not named
- Full states-served list not disclosed
- No named medical director
- FDA compounded-medication disclaimer not prominently displayed
- Corporate legal entity not disclosed
- Governing law and arbitration venue not disclosed
- Compounded liraglutide has a weaker weight-loss evidence base than semaglutide or tirzepatide
- Tirzepatide tier ($149/mo) less prominent than the advertised $99 starting price
Our Verdict
1st Optimal edges out Factor Health MD with a higher overall score of 6.7/10 and is particularly strong for GLP-1 therapy within a lab-driven functional-medicine program. Factor Health MD remains a solid alternative, especially if you're looking for broadest GLP-1 lineup — semaglutide, tirzepatide and liraglutide.
Choose 1st Optimal if…
You want GLP-1 therapy within a lab-driven functional-medicine program and a starting price around $99/mo.
Choose Factor Health MD if…
You want broadest GLP-1 lineup — semaglutide, tirzepatide and liraglutide and a starting price around $99/mo.
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Get started →1st Optimal vs Factor Health MD: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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