1st Optimal vs DrMedHealth
An in-depth comparison of two leading GLP-1 Providers
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1st Optimal
Best for: Patients wanting GLP-1 therapy within a lab-driven functional-medicine program
Visit 1st Optimal →
DrMedHealth
Best for: Cost-conscious patients seeking low-priced compounded GLP-1s from a LegitScript-certified clinic.
Visit DrMedHealth →1st Optimal and DrMedHealth are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, DrMedHealth starts at $199/mo, and DrMedHealth edges ahead overall (7.3 vs 6.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
1st Optimal
Pricing not publicly listed.
DrMedHealth
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What’s included
1st Optimal
Inclusions not disclosed.
DrMedHealth
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
1st Optimal
6.7/10
DrMedHealth
7.3/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | 1st Optimal | DrMedHealth |
|---|---|---|
| Starting Price | — | $199/mo |
| Features | 8 features | 8 features |
| States Available | Not disclosed | Not disclosed |
| Compounded | — | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About 1st Optimal
1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets. Its model pairs prescription GLP-1 therapy with at-home lab testing, blood-work interpretation, unlimited coaching, and personalized protocols framed around long-term weight loss and longevity. Care is delivered virtually by credentialed providers, and treatments ship to the home with no long-term contracts. The site does not publish monthly pricing or a state list.
Read our full 1st Optimal review →About DrMedHealth
DrMedHealth is a LegitScript-certified US telehealth platform for GLP-1 medical weight loss. Board-certified physicians prescribe compounded semaglutide from $199/mo and compounded tirzepatide from $299/mo, with FDA-approved branded options (Ozempic, Wegovy, Mounjaro) also available. The platform advertises roughly 2-hour physician review and free shipping, with compounded medication prepared by licensed US pharmacies. It operates across many states via state-specific pages (California, Michigan, Indiana, Utah and others). Compounded GLP-1s are not FDA-approved for quality, safety or efficacy.
Read our full DrMedHealth review →Pros & Cons
1st Optimal
What we like
- Offers both semaglutide and tirzepatide with injectable and oral formats
- Functional-medicine approach with at-home labs and blood-work interpretation
- Unlimited coaching and ongoing support included
- No long-term contracts
- Board-certified doctors and nurse practitioners referenced
Watch-outs
- No public monthly pricing disclosed
- No published state availability list
- Compounded vs branded sourcing not clarified on site
- Pricing only revealed after quiz or consultation
DrMedHealth
What we like
- LegitScript certified telehealth platform
- Low compounded pricing: semaglutide from $199/mo, tirzepatide from $299/mo
- Both compounded and FDA-approved branded options available
- Fast physician review (advertised ~2 hours) with free shipping
- Compounded by licensed US pharmacies
- Operates across many states with dedicated state pages
Watch-outs
- Compounded GLP-1s are not FDA-approved for safety, efficacy or quality
- Cash-pay model; insurance generally not accepted for medication
- Full list of available states not consolidated in one place
- Site is JavaScript-rendered, limiting easy review of full terms
Our Verdict
DrMedHealth edges out 1st Optimal with a higher overall score of 7.3/10 and is particularly strong for Cost-conscious patients seeking low-priced compounded GLP-1s from a LegitScript-certified clinic.. 1st Optimal remains a solid alternative, especially if you're looking for Patients wanting GLP-1 therapy within a lab-driven functional-medicine program.
Choose 1st Optimal if…
You want Patients wanting GLP-1 therapy within a lab-driven functional-medicine program.
Choose DrMedHealth if…
You want Cost-conscious patients seeking low-priced compounded GLP-1s from a LegitScript-certified clinic. and a starting price around $199/mo.
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Breeze Meds
Compounded GLP-1 access with named prescribers and 4-pharmacy network
From $169/mo
Get started →Telos Rx
Needle-free and microdosed compounded GLP-1 options with lab-monitored care
From $49/mo
Get started →GobyMeds
Budget-conscious shoppers
From $93/mo
Get started →1st Optimal vs DrMedHealth: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.