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1st Optimal vs Boston Medical Group

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
1st Optimal logo

1st Optimal

6.7
★★★☆☆3.4/5

Best for: GLP-1 therapy within a lab-driven functional-medicine program

Visit 1st Optimal
VS
Boston Medical Group logo

Boston Medical Group

7.8
★★★3.9/5

Best for: budget-conscious shoppers

Visit Boston Medical Group

1st Optimal and Boston Medical Group are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, both start around $99/mo, and Boston Medical Group edges ahead overall (7.8 vs 6.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

1st Optimal

Weight Loss Care membership — medication not includedBrand-name
$99/mo
semaglutide

Care membership only — the GLP-1 medication is billed separately and is not priced.

Boston Medical Group

StartingCompounded
$99/mo
semaglutide
Starting — 4 weeks of medicationCompounded
$149/mo
tirzepatide

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What’s included

1st Optimal

What the monthly price covers

Medication

Not disclosed

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Included

Boston Medical Group

What the monthly price covers

Medication

Included

Provider visits

Billed separately

Shipping

Not disclosed

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

1st Optimal

6.7/10

Overall

Boston Medical Group

7.8/10

Value25%

6.5A
vs
B
9.0

Effectiveness25%

7.0A
vs
B
7.5

User Experience15%

6.5A
vs
B
7.0

Trust & Safety15%

6.5A
vs
B
7.3

Accessibility10%

6.5A
vs
B
7.5

Support10%

7.4A
vs
B
7.4

Features & Coverage

Feature1st OptimalBoston Medical Group
Starting Price$99/mo$99/mo
Features8 features3 features
States AvailableNot disclosed7
Compounded✓ Yes
Brand Name✓ Yes
FSA/HSA Accepted
FDA WarningsNoneNone

About 1st Optimal

1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets. Its model pairs prescription GLP-1 therapy with at-home lab testing, blood-work interpretation, unlimited coaching, and personalized protocols framed around long-term weight loss and longevity. Care is delivered virtually by credentialed providers, and treatments ship to the home with no long-term contracts. The site does not publish monthly pricing or a state list.

Read our full 1st Optimal review →

About Boston Medical Group

Boston Medical Group sells compounded GLP-1s through its rx.bostonmedicalgroup.com storefront at 'as low as' $99/mo for semaglutide and $149/mo for tirzepatide, flat across every dose strength, with each plan sold as four weeks of medication rather than a calendar month. The same page also advertises 'Doctor-Led Weight Loss Plans Starting at $190/month', a figure that matches neither product card.

Read our full Boston Medical Group review →

Pros & Cons

1st Optimal

What we like

  • Offers both semaglutide and tirzepatide with injectable and oral formats
  • Functional-medicine approach with at-home labs and blood-work interpretation
  • Unlimited coaching and ongoing support included
  • No long-term contracts
  • Board-certified doctors and nurse practitioners referenced

Watch-outs

  • No public monthly pricing disclosed
  • No published state availability list
  • Compounded vs branded sourcing not clarified on site
  • Pricing only revealed after quiz or consultation

Boston Medical Group

What we like

  • Aggressively low monthly pricing
  • Both semaglutide and tirzepatide available
  • Compounded GLP-1 access

Watch-outs

  • Limited public information on program details

Our Verdict

Winner: Boston Medical Group

Boston Medical Group edges out 1st Optimal with a higher overall score of 7.8/10 and is particularly strong for budget-conscious shoppers. 1st Optimal remains a solid alternative, especially if you're looking for GLP-1 therapy within a lab-driven functional-medicine program.

Choose 1st Optimal if…

You want GLP-1 therapy within a lab-driven functional-medicine program and a starting price around $99/mo.

Choose Boston Medical Group if…

You want budget-conscious shoppers and a starting price around $99/mo.

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6.9

TMates

Nationwide compounded GLP-1 availability including Puerto Rico

7.9

Trimi Health

Budget-conscious shoppers

8.0

ShedRx

Mainstream telehealth GLP-1 access

1st Optimal vs Boston Medical Group: FAQ

1st Optimal and Boston Medical Group have the same lowest ongoing monthly price of $99/mo, so price alone won't separate them — compare what each plan includes instead.
Boston Medical Group scores higher overall at 7.8/10 versus 6.7/10, and is particularly strong for budget-conscious shoppers. That said, 1st Optimal is a better fit if you want GLP-1 therapy within a lab-driven functional-medicine program.
Boston Medical Group lists availability in 7 states, while 1st Optimal's state list is not publicly listed.
Neither 1st Optimal nor Boston Medical Group is currently an affiliate partner, so we earn no commission from either. We rank all providers editorially using the same six-dimension framework and disclose any commercial relationships.
1st Optimal and Boston Medical Group list the same lowest price for Semaglutide: $99/mo.

Key terms, explained

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Continue exploring 1st Optimal and Boston Medical Group head-to-heads in the same category.

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