1st Optimal vs Bodybuilding Health+
An in-depth comparison of two leading GLP-1 Providers
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1st Optimal
Best for: GLP-1 therapy within a lab-driven functional-medicine program
Visit 1st Optimal →
Bodybuilding Health+
Best for: fitness-brand compounded GLP-1 with hormone and performance programs
Visit Bodybuilding Health+ →1st Optimal and Bodybuilding Health+ are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 1st Optimal starts lower at $99/mo versus $179/mo, and Bodybuilding Health+ edges ahead overall (7.1 vs 6.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
1st Optimal
Care membership only — the GLP-1 medication is billed separately and is not priced.
Bodybuilding Health+
Genuine month-to-month rate, no prepay; a 12-month bundle drops it to $139/mo.
Genuine month-to-month rate, no prepay; longer bundles cost less per month.
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What’s included
1st Optimal
What the monthly price covers
Medication
Not disclosed
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Included
Bodybuilding Health+
What the monthly price covers
Medication
Included
Provider visits
Not disclosed
Shipping
Not disclosed
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
1st Optimal
6.7/10
Bodybuilding Health+
7.1/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | 1st Optimal | Bodybuilding Health+ |
|---|---|---|
| Starting Price | ✓$99/mo | $179/mo |
| Features | ✓8 features | 5 features |
| States Available | Not disclosed | Not disclosed |
| Compounded | — | ✓ Yes |
| Brand Name | ✓ Yes | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About 1st Optimal
1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets. Its model pairs prescription GLP-1 therapy with at-home lab testing, blood-work interpretation, unlimited coaching, and personalized protocols framed around long-term weight loss and longevity. Care is delivered virtually by credentialed providers, and treatments ship to the home with no long-term contracts. The site does not publish monthly pricing or a state list.
Read our full 1st Optimal review →About Bodybuilding Health+
Bodybuilding Health+ is a telehealth platform from the long-running Bodybuilding.com fitness brand, offering compounded semaglutide and tirzepatide alongside hormone, sexual-performance, and metabolic-support programs — a one-stop option for fitness-oriented patients. It's LegitScript-verified and prescribes through US-licensed clinicians. Compounded semaglutide starts at $179/month and tirzepatide at $209/month, both at the lower end of the market.
Read our full Bodybuilding Health+ review →Pros & Cons
1st Optimal
What we like
- Offers both semaglutide and tirzepatide with injectable and oral formats
- Functional-medicine approach with at-home labs and blood-work interpretation
- Unlimited coaching and ongoing support included
- No long-term contracts
- Board-certified doctors and nurse practitioners referenced
Watch-outs
- No public monthly pricing disclosed
- No published state availability list
- Compounded vs branded sourcing not clarified on site
- Pricing only revealed after quiz or consultation
Bodybuilding Health+
What we like
- Compounded semaglutide from $179/mo — at the lower end of the market
- Compounded tirzepatide from $209/mo — competitive with established platforms
- LegitScript verification seal displayed on the site
- Backed by Bodybuilding.com, a 25+ year fitness brand with 200+ Trustpilot reviews
- Programs span weight loss, hormone health, sexual performance, and metabolic support
Watch-outs
- State availability isn't listed publicly — gated behind signup; confirm your state ships first
- Pricing is 'starting at' — confirm your maintenance-dose cost before committing
- Fitness/performance framing may not suit patients wanting a clinical approach to obesity
- Pharmacy partners aren't named on the site
- LegitScript status couldn't be independently confirmed in the public database
Our Verdict
Bodybuilding Health+ edges out 1st Optimal with a higher overall score of 7.1/10 and is particularly strong for fitness-brand compounded GLP-1 with hormone and performance programs. 1st Optimal remains a solid alternative, especially if you're looking for GLP-1 therapy within a lab-driven functional-medicine program.
Choose 1st Optimal if…
You want GLP-1 therapy within a lab-driven functional-medicine program and a starting price around $99/mo.
Choose Bodybuilding Health+ if…
You want fitness-brand compounded GLP-1 with hormone and performance programs and a starting price around $179/mo.
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Maximus
Men seeking compounded GLP-1 alongside testosterone optimization
From $199.99/mo
Get started →Sesame Care
Brand-name GLP-1s at cash prices, no compounding
From $25/mo
Get started →Try Ageless
Lowest-tier compounded GLP-1 in injection, troche and sublingual forms
From $119/mo
Get started →1st Optimal vs Bodybuilding Health+: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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