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1st Optimal vs Better MedSpa

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
1st Optimal logo

1st Optimal

6.7
★★★☆☆3.4/5

Best for: GLP-1 therapy within a lab-driven functional-medicine program

Visit 1st Optimal
VS
Better MedSpa logo

Better MedSpa

6.7
★★★☆☆3.4/5

Best for: physician-led GLP-1 weight loss with in-person or telehealth options

Visit Better MedSpa

1st Optimal and Better MedSpa are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 1st Optimal starts at $99/mo, and both land at 6.7/10 overall. Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

1st Optimal

Weight Loss Care membership — medication not includedBrand-name
$99/mo
semaglutide

Care membership only — the GLP-1 medication is billed separately and is not priced.

Better MedSpa

Pricing not publicly listed.

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What’s included

1st Optimal

What the monthly price covers

Medication

Not disclosed

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Included

Better MedSpa

What the monthly price covers

Medication

Billed separately

Provider visits

Not disclosed

Shipping

Not disclosed

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

1st Optimal

6.7/10

Overall

Better MedSpa

6.7/10

Value25%

6.5A
vs
B
6.5

Effectiveness25%

7.0A
vs
B
7.0

User Experience15%

6.5A
vs
B
6.5

Trust & Safety15%

6.5A
vs
B
7.0

Accessibility10%

6.5A
vs
B
6.5

Support10%

7.4A
vs
B
6.9

Features & Coverage

Feature1st OptimalBetter MedSpa
Starting Price$99/mo
Features8 features7 features
States AvailableNot disclosed1
Compounded
Brand Name✓ Yes
FSA/HSA Accepted
FDA WarningsNoneNone

About 1st Optimal

1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets. Its model pairs prescription GLP-1 therapy with at-home lab testing, blood-work interpretation, unlimited coaching, and personalized protocols framed around long-term weight loss and longevity. Care is delivered virtually by credentialed providers, and treatments ship to the home with no long-term contracts. The site does not publish monthly pricing or a state list.

Read our full 1st Optimal review →

About Better MedSpa

Better MedSpa is a physician-led Chicago (Lincoln Park) practice offering medical weight loss and body contouring, with telehealth across Illinois. It prescribes GLP-1 medications including semaglutide and tirzepatide (oral and injectable) plus liraglutide as a daily injectable, delivered to patients' doors statewide. Care is overseen by medical director Dr. Brett Brechner, DO. The practice blends in-person services at its Lincoln Park location with Illinois-wide telehealth. Pricing is not published online and formulation is not specified, so confirm cost and details with the clinic.

Read our full Better MedSpa review →

Pros & Cons

1st Optimal

What we like

  • Offers both semaglutide and tirzepatide with injectable and oral formats
  • Functional-medicine approach with at-home labs and blood-work interpretation
  • Unlimited coaching and ongoing support included
  • No long-term contracts
  • Board-certified doctors and nurse practitioners referenced

Watch-outs

  • No public monthly pricing disclosed
  • No published state availability list
  • Compounded vs branded sourcing not clarified on site
  • Pricing only revealed after quiz or consultation

Better MedSpa

What we like

  • Broad menu: semaglutide, tirzepatide, and liraglutide
  • Both oral and injectable formulations offered
  • Physician-led; medical director Dr. Brett Brechner, DO
  • Both in-person Chicago visits and statewide telehealth
  • Doorstep delivery throughout Illinois

Watch-outs

  • Telehealth limited to Illinois only
  • No pricing published online
  • Compounded vs brand formulation not specified
  • Med-spa positioning blends weight loss with aesthetics

Our Verdict

Both 1st Optimal and Better MedSpa score equally well overall — the right choice depends on your priorities.

Choose 1st Optimal if…

You want GLP-1 therapy within a lab-driven functional-medicine program and a starting price around $99/mo.

Choose Better MedSpa if…

You want physician-led GLP-1 weight loss with in-person or telehealth options.

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7.6

Maximus

Men seeking compounded GLP-1 alongside testosterone optimization

8.0

Sesame Care

Brand-name GLP-1s at cash prices, no compounding

6.9

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Lowest-tier compounded GLP-1 in injection, troche and sublingual forms

1st Optimal vs Better MedSpa: FAQ

1st Optimal lists a lowest ongoing price of $99/mo, while Better MedSpa does not publicly list one. See the side-by-side pricing above for the full breakdown.
1st Optimal and Better MedSpa tie at 6.7/10 overall, so the right pick comes down to your priorities — 1st Optimal for GLP-1 therapy within a lab-driven functional-medicine program, Better MedSpa for physician-led GLP-1 weight loss with in-person or telehealth options.
Better MedSpa lists availability in 1 state, while 1st Optimal's state list is not publicly listed.
Neither 1st Optimal nor Better MedSpa is currently an affiliate partner, so we earn no commission from either. We rank all providers editorially using the same six-dimension framework and disclose any commercial relationships.

Key terms, explained

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Continue exploring 1st Optimal and Better MedSpa head-to-heads in the same category.

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