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1st Optimal vs Better MedSpa

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
1st Optimal logo

1st Optimal

6.7
★★★☆☆3.4/5

Best for: Patients wanting GLP-1 therapy within a lab-driven functional-medicine program

Visit 1st Optimal
VS
Better MedSpa logo

Better MedSpa

6.7
★★★☆☆3.4/5

Best for: Illinois residents wanting physician-led GLP-1 weight loss with in-person or telehealth options

Visit Better MedSpa

1st Optimal and Better MedSpa are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, both land at 6.7/10 overall. Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

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Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

1st Optimal

6.7/10

Overall

Better MedSpa

6.7/10

Value25%

6.5A
vs
B
6.5

Effectiveness25%

7.0A
vs
B
7.0

User Experience15%

6.5A
vs
B
6.5

Trust & Safety15%

6.5A
vs
B
7.0

Accessibility10%

6.5A
vs
B
6.5

Support10%

7.4A
vs
B
6.9

Features & Coverage

Feature1st OptimalBetter MedSpa
Starting Price
Features8 features7 features
States AvailableNot disclosed1
Compounded
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About 1st Optimal

1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets. Its model pairs prescription GLP-1 therapy with at-home lab testing, blood-work interpretation, unlimited coaching, and personalized protocols framed around long-term weight loss and longevity. Care is delivered virtually by credentialed providers, and treatments ship to the home with no long-term contracts. The site does not publish monthly pricing or a state list.

Read our full 1st Optimal review →

About Better MedSpa

Better MedSpa is a physician-led Chicago (Lincoln Park) practice offering medical weight loss and body contouring, with telehealth across Illinois. It prescribes GLP-1 medications including semaglutide and tirzepatide (oral and injectable) plus liraglutide as a daily injectable, delivered to patients' doors statewide. Care is overseen by medical director Dr. Brett Brechner, DO. The practice blends in-person services at its Lincoln Park location with Illinois-wide telehealth. Pricing is not published online and formulation is not specified, so confirm cost and details with the clinic.

Read our full Better MedSpa review →

Pros & Cons

1st Optimal

What we like

  • Offers both semaglutide and tirzepatide with injectable and oral formats
  • Functional-medicine approach with at-home labs and blood-work interpretation
  • Unlimited coaching and ongoing support included
  • No long-term contracts
  • Board-certified doctors and nurse practitioners referenced

Watch-outs

  • No public monthly pricing disclosed
  • No published state availability list
  • Compounded vs branded sourcing not clarified on site
  • Pricing only revealed after quiz or consultation

Better MedSpa

What we like

  • Broad menu: semaglutide, tirzepatide, and liraglutide
  • Both oral and injectable formulations offered
  • Physician-led; medical director Dr. Brett Brechner, DO
  • Both in-person Chicago visits and statewide telehealth
  • Doorstep delivery throughout Illinois

Watch-outs

  • Telehealth limited to Illinois only
  • No pricing published online
  • Compounded vs brand formulation not specified
  • Med-spa positioning blends weight loss with aesthetics

Our Verdict

Both 1st Optimal and Better MedSpa score equally well overall — the right choice depends on your priorities.

Choose 1st Optimal if…

You want Patients wanting GLP-1 therapy within a lab-driven functional-medicine program.

Choose Better MedSpa if…

You want Illinois residents wanting physician-led GLP-1 weight loss with in-person or telehealth options.

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1st Optimal vs Better MedSpa: FAQ

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