1st Optimal vs Bayan Health
An in-depth comparison of two leading GLP-1 Providers
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1st Optimal
Best for: GLP-1 therapy within a lab-driven functional-medicine program
Visit 1st Optimal →Bayan Health
Best for: openly published flat monthly pricing with microdose tiers below standard
Visit Bayan Health →1st Optimal and Bayan Health are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, both start around $99/mo, and Bayan Health edges ahead overall (7.3 vs 6.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
1st Optimal
Care membership only — the GLP-1 medication is billed separately and is not priced.
Bayan Health
Microdose tier, sold with vitamin B6. Billed as a monthly subscription.
Microdose tier, sold with vitamin B6. Billed as a monthly subscription.
Sold with vitamin B6. Billed as a monthly subscription.
Sold with vitamin B6. Billed as a monthly subscription.
Oral drop formulation. No published pharmacokinetic data for this route.
Oral drop formulation. No published pharmacokinetic data for this route.
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What’s included
1st Optimal
What the monthly price covers
Medication
Not disclosed
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Included
Bayan Health
Inclusions not disclosed.
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
1st Optimal
6.7/10
Bayan Health
7.3/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | 1st Optimal | Bayan Health |
|---|---|---|
| Starting Price | $99/mo | $99/mo |
| Features | ✓8 features | 2 features |
| States Available | Not disclosed | Not disclosed |
| Compounded | — | ✓ Yes |
| Brand Name | ✓ Yes | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About 1st Optimal
1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets. Its model pairs prescription GLP-1 therapy with at-home lab testing, blood-work interpretation, unlimited coaching, and personalized protocols framed around long-term weight loss and longevity. Care is delivered virtually by credentialed providers, and treatments ship to the home with no long-term contracts. The site does not publish monthly pricing or a state list.
Read our full 1st Optimal review →About Bayan Health
Bayan Health (bayantelehealth.com) is a physician-led GLP-1 telehealth brand selling compounded semaglutide and tirzepatide as once-weekly injections paired with vitamin B6, plus needle-free oral drop versions of both. Pricing is published openly on a WooCommerce storefront as a flat monthly subscription per protocol, with microdose tiers priced below the standard ones. Purchases are marked HSA/FSA eligible.
Read our full Bayan Health review →Pros & Cons
1st Optimal
What we like
- Offers both semaglutide and tirzepatide with injectable and oral formats
- Functional-medicine approach with at-home labs and blood-work interpretation
- Unlimited coaching and ongoing support included
- No long-term contracts
- Board-certified doctors and nurse practitioners referenced
Watch-outs
- No public monthly pricing disclosed
- No published state availability list
- Compounded vs branded sourcing not clarified on site
- Pricing only revealed after quiz or consultation
Bayan Health
What we like
- Prices published openly on the storefront — every protocol shows a flat monthly figure with no gate
- Microdose tiers priced below the standard tiers, which is uncommon and useful for low-dose starters
- Purchases marked HSA/FSA eligible
- Both semaglutide and tirzepatide offered, so switching molecules does not mean switching providers
Watch-outs
- Oral drop formulations are sold without any published pharmacokinetic evidence for that route
- States served are not enumerated anywhere on the site
- No LegitScript badge displayed and no dispensing pharmacy named
- Four products are advertised as coming soon, including retatrutide, which is not FDA-approved for anything
Our Verdict
Bayan Health edges out 1st Optimal with a higher overall score of 7.3/10 and is particularly strong for openly published flat monthly pricing with microdose tiers below standard. 1st Optimal remains a solid alternative, especially if you're looking for GLP-1 therapy within a lab-driven functional-medicine program.
Choose 1st Optimal if…
You want GLP-1 therapy within a lab-driven functional-medicine program and a starting price around $99/mo.
Choose Bayan Health if…
You want openly published flat monthly pricing with microdose tiers below standard and a starting price around $99/mo.
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RNK Health
Compounded GLP-1 alongside NAD+, peptide and longevity add-ons
From $197/mo
Get started →Wellorithm
Compounded GLP-1 access with oral tablet options across 49 states
From $147/mo
Get started →SkinnyRx
Mainstream telehealth GLP-1 access
From $149.25/mo
Get started →1st Optimal vs Bayan Health: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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