10rx vs Zappy Health
An in-depth comparison of two leading GLP-1 Providers
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10rx
Best for: budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons
Visit 10rx →
Zappy Health
Best for: people wanting both compounded and brand-name GLP-1 with flat pricing that doesn't rise with dose
Visit Zappy Health →10rx and Zappy Health are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 10rx starts lower at $99.67/mo versus $159/mo, and 10rx edges ahead overall (7.1 vs 6.9 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
10rx
Compounded; GLP-1 options as low as under $100/mo
Compounded GLP-1 + GIP
Zappy Health
From $159/mo (9-mo); $199 (3-mo); $249 month-to-month; flat across doses
From $299/mo (9-mo); $329 (3-mo); $359 month-to-month; flat across doses
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What’s included
10rx
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Zappy Health
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
10rx
7.1/10
Zappy Health
6.9/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | 10rx | Zappy Health |
|---|---|---|
| Starting Price | ✓$99.67/mo | $159/mo |
| Features | 8 features | 8 features |
| States Available | Not disclosed | 42 |
| Compounded | — | — |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About 10rx
10rx is a nationwide GLP-1 telehealth program offering compounded weight-loss medication at low flat monthly rates: semaglutide at $99.67/month and tirzepatide at $149.67/month, with NAD+ and sermorelin also offered for energy and recovery. You take a free online health quiz, a board-certified telehealth doctor reviews your history and prescribes if appropriate, and licensed pharmacy partners ship discreetly. 10rx says it ships to all 50 states, but it doesn't publish its operating company, name its pharmacies, or post a terms page.
Read our full 10rx review →About Zappy Health
Zappy Health is a telehealth weight-loss platform offering both compounded and brand-name GLP-1: compounded semaglutide from $159/month and tirzepatide from $299/month, plus brand Wegovy and Zepbound. Pricing is flat — it doesn't rise with your dose — and longer subscriptions cost less. You complete an online visit and a licensed clinician prescribes if appropriate. Zappy operates in about 42 states (not HI, AL, AR, CA, KS, MI, MN or MS). Note that some third-party reports raise pharmacy-sourcing concerns.
Read our full Zappy Health review →Pros & Cons
10rx
What we like
- Very low pricing — compounded semaglutide $99.67/month and tirzepatide $149.67/month
- Free online health quiz with board-certified telehealth doctors reviewing eligibility
- Offers NAD+ and sermorelin alongside GLP-1, for energy and muscle recovery
- Says it ships to all 50 states with discreet delivery from licensed pharmacy partners
Watch-outs
- Doesn't publish its legal operating entity, so accountability is hard to verify
- Pharmacy partners are described as licensed but none are named
- No terms-of-service page is posted, and FAQ answers load only via script
- Compounded semaglutide and tirzepatide only — no brand-name or oral options
- No LegitScript or third-party accreditation is shown on the site
Zappy Health
What we like
- Both compounded GLP-1 and brand-name Wegovy/Zepbound available
- Flat pricing that doesn't increase as your dose goes up
- Cheaper on longer subscriptions — compounded semaglutide from $159/month
- Online visit with a licensed clinician; no insurance required
Watch-outs
- Third-party reports of an order arriving with an unlicensed-pharmacy label
- Not available in 8 states (HI, AL, AR, CA, KS, MI, MN, MS)
- Operating legal entity isn't clearly disclosed on the site
- Lowest prices require a 9-month commitment
Our Verdict
10rx edges out Zappy Health with a higher overall score of 7.1/10 and is particularly strong for budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons. Zappy Health remains a solid alternative, especially if you're looking for people wanting both compounded and brand-name GLP-1 with flat pricing that doesn't rise with dose.
Choose 10rx if…
You want budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons and a starting price around $99.67/mo.
Choose Zappy Health if…
You want people wanting both compounded and brand-name GLP-1 with flat pricing that doesn't rise with dose and a starting price around $159/mo.
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Try Ageless
Lowest-tier compounded GLP-1 in injection, troche and sublingual forms
From $119/mo
Get started →Sunlight
Compounded GLP-1 with unlimited telehealth visits and free shipping
From $159/mo
Get started →MadeMed
Compounded GLP-1 in both injection and oral forms
From $219/mo
Get started →10rx vs Zappy Health: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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