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10rx vs Zappy Health

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
10rx logo

10rx

7.1
★★★3.6/5

Best for: budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons

Visit 10rx
VS
Zappy Health logo

Zappy Health

6.9
★★★3.5/5

Best for: people wanting both compounded and brand-name GLP-1 with flat pricing that doesn't rise with dose

Visit Zappy Health

10rx and Zappy Health are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 10rx starts lower at $99.67/mo versus $159/mo, and 10rx edges ahead overall (7.1 vs 6.9 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

10rx

Injectablecompounded injection
$99.67/mo
semaglutide

Compounded; GLP-1 options as low as under $100/mo

Injectablecompounded injection
$149.67/mo
tirzepatide

Compounded GLP-1 + GIP

Zappy Health

Injectablecompounded injection
$159/mo
semaglutide

From $159/mo (9-mo); $199 (3-mo); $249 month-to-month; flat across doses

Injectablecompounded injection
$299/mo
tirzepatide

From $299/mo (9-mo); $329 (3-mo); $359 month-to-month; flat across doses

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What’s included

10rx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Zappy Health

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

10rx

7.1/10

Overall

Zappy Health

6.9/10

Value25%

8.5A
vs
B
7.5

Effectiveness25%

7.0A
vs
B
7.0

User Experience15%

7.0A
vs
B
7.0

Trust & Safety15%

5.3A
vs
B
5.8

Accessibility10%

7.5A
vs
B
7.5

Support10%

6.4A
vs
B
5.9

Features & Coverage

Feature10rxZappy Health
Starting Price$99.67/mo$159/mo
Features8 features8 features
States AvailableNot disclosed42
Compounded
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About 10rx

10rx is a nationwide GLP-1 telehealth program offering compounded weight-loss medication at low flat monthly rates: semaglutide at $99.67/month and tirzepatide at $149.67/month, with NAD+ and sermorelin also offered for energy and recovery. You take a free online health quiz, a board-certified telehealth doctor reviews your history and prescribes if appropriate, and licensed pharmacy partners ship discreetly. 10rx says it ships to all 50 states, but it doesn't publish its operating company, name its pharmacies, or post a terms page.

Read our full 10rx review →

About Zappy Health

Zappy Health is a telehealth weight-loss platform offering both compounded and brand-name GLP-1: compounded semaglutide from $159/month and tirzepatide from $299/month, plus brand Wegovy and Zepbound. Pricing is flat — it doesn't rise with your dose — and longer subscriptions cost less. You complete an online visit and a licensed clinician prescribes if appropriate. Zappy operates in about 42 states (not HI, AL, AR, CA, KS, MI, MN or MS). Note that some third-party reports raise pharmacy-sourcing concerns.

Read our full Zappy Health review →

Pros & Cons

10rx

What we like

  • Very low pricing — compounded semaglutide $99.67/month and tirzepatide $149.67/month
  • Free online health quiz with board-certified telehealth doctors reviewing eligibility
  • Offers NAD+ and sermorelin alongside GLP-1, for energy and muscle recovery
  • Says it ships to all 50 states with discreet delivery from licensed pharmacy partners

Watch-outs

  • Doesn't publish its legal operating entity, so accountability is hard to verify
  • Pharmacy partners are described as licensed but none are named
  • No terms-of-service page is posted, and FAQ answers load only via script
  • Compounded semaglutide and tirzepatide only — no brand-name or oral options
  • No LegitScript or third-party accreditation is shown on the site

Zappy Health

What we like

  • Both compounded GLP-1 and brand-name Wegovy/Zepbound available
  • Flat pricing that doesn't increase as your dose goes up
  • Cheaper on longer subscriptions — compounded semaglutide from $159/month
  • Online visit with a licensed clinician; no insurance required

Watch-outs

  • Third-party reports of an order arriving with an unlicensed-pharmacy label
  • Not available in 8 states (HI, AL, AR, CA, KS, MI, MN, MS)
  • Operating legal entity isn't clearly disclosed on the site
  • Lowest prices require a 9-month commitment

Our Verdict

Winner: 10rx

10rx edges out Zappy Health with a higher overall score of 7.1/10 and is particularly strong for budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons. Zappy Health remains a solid alternative, especially if you're looking for people wanting both compounded and brand-name GLP-1 with flat pricing that doesn't rise with dose.

Choose 10rx if…

You want budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons and a starting price around $99.67/mo.

Choose Zappy Health if…

You want people wanting both compounded and brand-name GLP-1 with flat pricing that doesn't rise with dose and a starting price around $159/mo.

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6.9

Try Ageless

Lowest-tier compounded GLP-1 in injection, troche and sublingual forms

7.3

Sunlight

Compounded GLP-1 with unlimited telehealth visits and free shipping

7.4

MadeMed

Compounded GLP-1 in both injection and oral forms

10rx vs Zappy Health: FAQ

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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.