10rx vs Wholesome Clinic
An in-depth comparison of two leading GLP-1 Providers
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10rx
Best for: budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons
Visit 10rx →
Wholesome Clinic
Best for: Multi-state telehealth pairing compounded GLP-1 weight loss with integrative psychiatry
Visit Wholesome Clinic →10rx and Wholesome Clinic are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 10rx starts lower at $99.67/mo versus $109/mo, and Wholesome Clinic edges ahead overall (7.6 vs 7.1 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
10rx
Compounded; GLP-1 options as low as under $100/mo
Compounded GLP-1 + GIP
Wholesome Clinic
Self-pay; $109/$149/$199 per month by dose plan
Self-pay; $149-$199+ per month by dose plan
Self-pay; $249/$299/$349 per month by dose plan
Self-pay; $349/$449/$549 per month by dose plan
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What’s included
10rx
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Wholesome Clinic
What the monthly price covers
Medication
Included
Provider visits
Billed separately
Shipping
Not disclosed
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
10rx
7.1/10
Wholesome Clinic
7.6/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | 10rx | Wholesome Clinic |
|---|---|---|
| Starting Price | ✓$99.67/mo | $109/mo |
| Features | ✓8 features | 6 features |
| States Available | Not disclosed | 7 |
| Compounded | — | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About 10rx
10rx is a nationwide GLP-1 telehealth program offering compounded weight-loss medication at low flat monthly rates: semaglutide at $99.67/month and tirzepatide at $149.67/month, with NAD+ and sermorelin also offered for energy and recovery. You take a free online health quiz, a board-certified telehealth doctor reviews your history and prescribes if appropriate, and licensed pharmacy partners ship discreetly. 10rx says it ships to all 50 states, but it doesn't publish its operating company, name its pharmacies, or post a terms page.
Read our full 10rx review →About Wholesome Clinic
Wholesome Clinic is a Frisco, Texas integrative-psychiatry and wellness practice offering medical weight loss via telehealth across seven states. Providers prescribe compounded semaglutide and tirzepatide (oral dissolving tablet or weekly injectable), plus brand Wegovy and Zepbound when clinically appropriate. Self-pay medication runs from $109/month for compounded semaglutide, with a $149 initial evaluation and $75 follow-ups billed separately.
Read our full Wholesome Clinic review →Pros & Cons
10rx
What we like
- Very low pricing — compounded semaglutide $99.67/month and tirzepatide $149.67/month
- Free online health quiz with board-certified telehealth doctors reviewing eligibility
- Offers NAD+ and sermorelin alongside GLP-1, for energy and muscle recovery
- Says it ships to all 50 states with discreet delivery from licensed pharmacy partners
Watch-outs
- Doesn't publish its legal operating entity, so accountability is hard to verify
- Pharmacy partners are described as licensed but none are named
- No terms-of-service page is posted, and FAQ answers load only via script
- Compounded semaglutide and tirzepatide only — no brand-name or oral options
- No LegitScript or third-party accreditation is shown on the site
Wholesome Clinic
What we like
- Publishes standing per-dose self-pay prices for compounded semaglutide and tirzepatide, oral and injectable
- Compounded semaglutide from $109/mo (oral) or $149/mo (injectable); brand Wegovy/Zepbound offered when appropriate
- Telehealth across seven states plus an in-person option at its Frisco, TX office
Watch-outs
- $149 initial evaluation and $75 follow-up visits are billed separately from medication
- Filled through your 'preferred pharmacy' — no single named compounding pharmacy partner
- No LegitScript certification displayed
Our Verdict
Wholesome Clinic edges out 10rx with a higher overall score of 7.6/10 and is particularly strong for Multi-state telehealth pairing compounded GLP-1 weight loss with integrative psychiatry. 10rx remains a solid alternative, especially if you're looking for budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons.
Choose 10rx if…
You want budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons and a starting price around $99.67/mo.
Choose Wholesome Clinic if…
You want Multi-state telehealth pairing compounded GLP-1 weight loss with integrative psychiatry and a starting price around $109/mo.
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Maximus
Men seeking compounded GLP-1 alongside testosterone optimization
From $199.99/mo
Get started →Sesame Care
Brand-name GLP-1s (Wegovy, Zepbound) at LillyDirect/NovoCare cash prices — no compounding
From $25/mo
Get started →MEDVi
Patients who want the option to switch between compounded and brand-name GLP-1 through one provider
From $99/mo
Get started →10rx vs Wholesome Clinic: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.