10rx vs Synergy Rx
An in-depth comparison of two leading GLP-1 Providers
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10rx
Best for budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-onsStarting at $99.67/mo
Synergy Rx
Best for broadest drug catalog in the Lion MD white-label clusterStarting at $199/mo
Side-by-Side Comparison
| Feature | 10rx | Synergy Rx |
|---|---|---|
| Overall Score | 7.0/10 | ✓7.4/10 |
| Starting Price | ✓$99.67/mo | $199/mo |
| Editorial Rating | 3.5 ★ /5 | ✓3.7 ★ /5 |
| Features | ✓8 features | 6 features |
| States Available | 0 | ✓50 |
| Compounded | — | ✓ Yes |
| Brand Name | — | ✓ Yes |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
Pros & Cons
10rx
What we like
- Very low pricing — compounded semaglutide $99.67/month and tirzepatide $149.67/month
- Free online health quiz with board-certified telehealth doctors reviewing eligibility
- Offers NAD+ and sermorelin alongside GLP-1, for energy and muscle recovery
- Says it ships to all 50 states with discreet delivery from licensed pharmacy partners
Watch-outs
- Doesn't publish its legal operating entity, so accountability is hard to verify
- Pharmacy partners are described as licensed but none are named
- No terms-of-service page is posted, and FAQ answers load only via script
- Compounded semaglutide and tirzepatide only — no brand-name or oral options
- No LegitScript or third-party accreditation is shown on the site
Synergy Rx
What we like
- Broad catalog: compounded sema/tirz in injection and oral dissolving tablet, plus brand Ozempic, Wegovy, and Mounjaro
- Claims 50,000+ patients as of late 2025
- Available in all 50 states, subject to state telehealth rules
- Same medical team as Breeze Meds and Care Bare Rx (Dr. Carr and Dr. Tenbrink via Lion MD)
- Four named 503A pharmacy partners (Belmar, Strive, Epiq Scripts, Casa Pharma Rx)
- LegitScript Certified
Watch-outs
- Same clinician network and pharmacies as Breeze Meds and Care Bare Rx — three brands on one underlying operation
- Mandatory individual arbitration + class-action waiver (30-day opt-out from signup)
- Consultation fees non-refundable and all prescription sales final
- Disclaims liability for third-party pharmacy medication quality
- Full active-state list requires contacting support, not published
- Correct site is synergyrx.co — synergyrx.com is an unrelated parked domain
Our Verdict
Synergy Rx edges out 10rx with a higher overall score of 7.4/10 and is particularly strong for broadest drug catalog in the Lion MD white-label cluster. 10rx remains a solid alternative, especially if you're looking for budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons.
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.