10rx vs Southern Vitality and Weight Loss
An in-depth comparison of two leading GLP-1 Providers
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Southern Vitality and Weight Loss
Best for: cheap compounded GLP-1 from a provider that names its pharmacies
Visit Southern Vitality and Weight Loss →10rx and Southern Vitality and Weight Loss are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Southern Vitality and Weight Loss starts lower at $99/mo versus $99.67/mo, and Southern Vitality and Weight Loss edges ahead overall (7.8 vs 7.1 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
10rx
Compounded; GLP-1 options as low as under $100/mo
Compounded GLP-1 + GIP
Southern Vitality and Weight Loss
"GLP-1 starting as low as $99/mo"; flexible financing available
"GLP-1 starting as low as $99/mo"; flexible financing available
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What’s included
10rx
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Southern Vitality and Weight Loss
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
10rx
7.1/10
Southern Vitality and Weight Loss
7.8/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | 10rx | Southern Vitality and Weight Loss |
|---|---|---|
| Starting Price | $99.67/mo | ✓$99/mo |
| Features | 8 features | 8 features |
| States Available | Not disclosed | Not disclosed |
| Compounded | — | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About 10rx
10rx is a nationwide GLP-1 telehealth program offering compounded weight-loss medication at low flat monthly rates: semaglutide at $99.67/month and tirzepatide at $149.67/month, with NAD+ and sermorelin also offered for energy and recovery. You take a free online health quiz, a board-certified telehealth doctor reviews your history and prescribes if appropriate, and licensed pharmacy partners ship discreetly. 10rx says it ships to all 50 states, but it doesn't publish its operating company, name its pharmacies, or post a terms page.
Read our full 10rx review →About Southern Vitality and Weight Loss
Southern Vitality and Weight Loss is a physician-supervised telehealth weight-loss program (operating since 2012) offering compounded semaglutide and tirzepatide starting as low as $99/mo, plus vitamin injections and peptides. It includes a free telehealth consult, free shipping, and bi-weekly check-ins, with no membership or hidden fees. Unusually, it names its compounding pharmacy partners — PerfectRx, The Pharmacy Hub, and RX Compound Store. The company is Georgia-based and does not publish its state-availability list.
Read our full Southern Vitality and Weight Loss review →Pros & Cons
10rx
What we like
- Very low pricing — compounded semaglutide $99.67/month and tirzepatide $149.67/month
- Free online health quiz with board-certified telehealth doctors reviewing eligibility
- Offers NAD+ and sermorelin alongside GLP-1, for energy and muscle recovery
- Says it ships to all 50 states with discreet delivery from licensed pharmacy partners
Watch-outs
- Doesn't publish its legal operating entity, so accountability is hard to verify
- Pharmacy partners are described as licensed but none are named
- No terms-of-service page is posted, and FAQ answers load only via script
- Compounded semaglutide and tirzepatide only — no brand-name or oral options
- No LegitScript or third-party accreditation is shown on the site
Southern Vitality and Weight Loss
What we like
- Compounded GLP-1 (semaglutide and tirzepatide) starting as low as $99/mo
- Names its compounding pharmacy partners (PerfectRx, The Pharmacy Hub, RX Compound Store) — uncommon transparency
- Free telehealth consult and free shipping; no membership or hidden fees
- Bi-weekly check-ins; operating since 2012
- Flexible monthly financing available at checkout
Watch-outs
- All sales final once a prescription is approved and sent to the pharmacy
- States of operation not published
- Not LegitScript-certified (no certification displayed)
- Prescribing medical group not named (only "licensed providers")
Our Verdict
Southern Vitality and Weight Loss edges out 10rx with a higher overall score of 7.8/10 and is particularly strong for cheap compounded GLP-1 from a provider that names its pharmacies. 10rx remains a solid alternative, especially if you're looking for low-cost compounded GLP-1 with NAD+ and sermorelin add-ons.
Choose 10rx if…
You want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons and a starting price around $99.67/mo.
Choose Southern Vitality and Weight Loss if…
You want cheap compounded GLP-1 from a provider that names its pharmacies and a starting price around $99/mo.
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Sesame Care
Brand-name GLP-1s at cash prices, no compounding
From $25/mo
Get started →Try Ageless
Lowest-tier compounded GLP-1 in injection, troche and sublingual forms
From $119/mo
Get started →Sunlight
Compounded GLP-1 with unlimited telehealth visits and free shipping
From $159/mo
Get started →10rx vs Southern Vitality and Weight Loss: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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