Always verify pricing and state availability on the provider's website before signing up.How our reviews work →

10rx vs Sesame Care

An in-depth comparison of two leading GLP-1 Providers

WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more

By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
10rx logo

10rx

7.1
★★★3.6/5

Best for: budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons

Visit 10rx
VS
Sesame Care logo

Sesame Care

8.0
★★★★4/5

Best for: Brand-name GLP-1s (Wegovy, Zepbound) at LillyDirect/NovoCare cash prices — no compounding

Visit Sesame Care

10rx and Sesame Care are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Sesame Care starts lower at $59/mo versus $99.67/mo, and Sesame Care edges ahead overall (8.0 vs 7.1 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

10rx

Injectablecompounded injection
$99.67/mo
semaglutide

Compounded; GLP-1 options as low as under $100/mo

Injectablecompounded injection
$149.67/mo
tirzepatide

Compounded GLP-1 + GIP

Sesame Care

Annual planCompounded
$59/mo
clinical care only — medication billed separately

Month-to-Month $99/mo, 3-Month $39/mo, 6-Month $49/mo, Annual $59/mo; includes video visits, unlimited messaging, follow-ups, labs (savings $60/3mo, $180/6mo, $480/yr)

all doses 0.25-2.4mgCompounded
$349$199/mo
Save 43% right now
semaglutide (wegovy)

$199/mo first two months, new self-pay patients, lowest doses (0.25/0.5mg) only; FAQ terms state offer valid through 2026-06-30 but $199 still advertised on 2026-07-14

1.5mg / 4mgCompounded · oral
$149/mo
semaglutide (wegovy)

low doses

9mg / 25mgCompounded · oral
$299/mo
semaglutide (wegovy)

high doses; maintenance dose $50/mo cheaper than Wegovy injection

0.25mg / 0.5mg / 1mgCompounded
$349$199/mo
Save 43% right now
semaglutide (ozempic)

NEW published pricing: $199 first two months (same new-self-pay intro terms as Wegovy); 2mg is $499/mo

2.5mgCompounded
$299/mo
tirzepatide (zepbound)

$399/mo for 5mg; $449/mo for 7.5mg, 10mg, 12.5mg, 15mg — unchanged vs stored

2.5mgCompounded
$299/mo
tirzepatide (zepbound)

$399/mo 5mg, $499/mo 7.5mg, $699/mo 10-15mg (program page shows $398/$698 — Sesame's own pages disagree by $1)

starts atCompounded
$1086/mo
tirzepatide (zepbound)

NEW row on program page: 'Zepbound® Tirzepatide Starts at $1,086 per / mo' (retail-channel pen, distinct from LillyDirect KwikPen)

0.8mgCompounded · oral
$149/mo
orforglipron (foundayo)

NEW published pricing: $199/mo (2.5mg), $299/mo (5.5mg, 9mg), $349/mo (14.5mg, 17.2mg); previously feature-only with no pricing row

as low asCompounded
$25/mo
semaglutide or tirzepatide (with commercial insurance)

'Price with insurance: as low as $25 per / mo.' — copay varies by plan/PA outcome

Get alerted when GLP-1 prices drop

Join the GLP-1 price-watch list — we re-verify 400+ providers' prices on their own sites and email you when tracked prices move.

What’s included

10rx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Sesame Care

Inclusions not disclosed.

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

10rx

7.1/10

Overall

Sesame Care

8.0/10

Value25%

8.5A
vs
B
7.5

Effectiveness25%

7.0A
vs
B
9.0

User Experience15%

7.0A
vs
B
8.0

Trust & Safety15%

5.3A
vs
B
8.0

Accessibility10%

7.5A
vs
B
6.5

Support10%

6.4A
vs
B
8.0

Features & Coverage

Feature10rxSesame Care
Starting Price$99.67/mo$59/mo
Features8 features8 features
States AvailableNot disclosedNot disclosed
Compounded✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About 10rx

10rx is a nationwide GLP-1 telehealth program offering compounded weight-loss medication at low flat monthly rates: semaglutide at $99.67/month and tirzepatide at $149.67/month, with NAD+ and sermorelin also offered for energy and recovery. You take a free online health quiz, a board-certified telehealth doctor reviews your history and prescribes if appropriate, and licensed pharmacy partners ship discreetly. 10rx says it ships to all 50 states, but it doesn't publish its operating company, name its pharmacies, or post a terms page.

Read our full 10rx review →

About Sesame Care

Sesame is a transparent-pricing telehealth marketplace that connects patients directly with independent provider practices — distinct from the stocked-formulary model of most weight-loss platforms. Its weight-loss vertical is brand-name only (no compounding): a $39–$99/month subscription covers clinical care, while medication is billed separately at cash-pay rates, including Zepbound from $299 via LillyDirect and a Wegovy self-pay promo at $199/month.

Read our full Sesame Care review →

Pros & Cons

10rx

What we like

  • Very low pricing — compounded semaglutide $99.67/month and tirzepatide $149.67/month
  • Free online health quiz with board-certified telehealth doctors reviewing eligibility
  • Offers NAD+ and sermorelin alongside GLP-1, for energy and muscle recovery
  • Says it ships to all 50 states with discreet delivery from licensed pharmacy partners

Watch-outs

  • Doesn't publish its legal operating entity, so accountability is hard to verify
  • Pharmacy partners are described as licensed but none are named
  • No terms-of-service page is posted, and FAQ answers load only via script
  • Compounded semaglutide and tirzepatide only — no brand-name or oral options
  • No LegitScript or third-party accreditation is shown on the site

Sesame Care

What we like

  • Marketplace transparency — pick a named provider with a displayed price before booking, unlike most opaque telehealth intake
  • BBB-accredited and LegitScript-verified
  • LillyDirect partnership unlocks Zepbound vial and KwikPen cash pricing matching Lilly's lowest direct rates ($299 at lowest dose)
  • Wegovy self-pay promo ($199/mo for first two months, lowest dose, new self-pay) — among the lowest brand-Wegovy cash prices
  • Honest subscription scope — clinical care only, medication billed separately
  • Stocks both Wegovy pill ($149/mo low doses) and Foundayo orforglipron alongside injectables
  • Lab work included in subscription for 41 states (excludes AZ/HI/ND/NJ/NY/OK/RI/SD/WY)
  • Insurance route ($25/mo possible) is viable — providers assist with prior authorization

Watch-outs

  • Marketplace model means clinician credentials and quality vary provider to provider
  • Statewide availability can't be listed — it depends on which marketplace providers are licensed in your state
  • No in-house pharmacy — fulfillment splits across LillyDirect, NovoCare, and your retail pharmacy
  • Restrictive refunds — full refund only if you cancel 3+ hours before the first visit; no refund once the visit occurs
  • Subscription commitment required — no genuine pay-per-visit option for weight loss
  • Wegovy $199/mo promo applies only to new self-pay patients at the lowest dose; $349/mo after month 2
  • Wegovy pill high doses ($299/mo for 9mg/25mg) cost about 2x the low-dose price as you titrate up
  • Zepbound KwikPen high doses ($699/mo for 10–15mg) approach Lilly's list price

Our Verdict

Winner: Sesame Care

Sesame Care edges out 10rx with a higher overall score of 8.0/10 and is particularly strong for Brand-name GLP-1s (Wegovy, Zepbound) at LillyDirect/NovoCare cash prices — no compounding. 10rx remains a solid alternative, especially if you're looking for budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons.

Choose 10rx if…

You want budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons and a starting price around $99.67/mo.

Choose Sesame Care if…

You want Brand-name GLP-1s (Wegovy, Zepbound) at LillyDirect/NovoCare cash prices — no compounding and a starting price around $59/mo.

Ready to start? Vetted GLP-1 providers

Vetted telehealth providers that prescribe GLP-1 online.

No insurance needed · vetted by our editors

WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more

7.4

Breeze Meds

Compounded GLP-1 access with named prescribers and 4-pharmacy network

8.1

GobyMeds

Budget-conscious shoppers

7.6

RNK Health

Compounded GLP-1 alongside NAD+, peptide and longevity add-ons

10rx vs Sesame Care: FAQ

Key terms, explained

New to GLP-1s? Tap any term for a quick, plain-English definition.

Continue exploring 10rx and Sesame Care head-to-heads in the same category.

Or see the full category ranking.

Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.