10rx vs Primary Clinic (Direct GLP)
An in-depth comparison of two leading GLP-1 Providers
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
10rx
Best for budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-onsStarting at $99.67/mo
Primary Clinic (Direct GLP)
Best for GLP-1 at wholesale cost inside a Direct Primary Care membershipStarting at $65/mo
Side-by-Side Comparison
| Feature | 10rx | Primary Clinic (Direct GLP) |
|---|---|---|
| Overall Score | 7.0/10 | ✓8.0/10 |
| Starting Price | $99.67/mo | ✓$65/mo |
| Editorial Rating | 3.5 ★ /5 | ✓4 ★ /5 |
| Features | ✓8 features | 4 features |
| States Available | 0 | ✓10 |
| Compounded | — | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
Pros & Cons
10rx
What we like
- Very low pricing — compounded semaglutide $99.67/month and tirzepatide $149.67/month
- Free online health quiz with board-certified telehealth doctors reviewing eligibility
- Offers NAD+ and sermorelin alongside GLP-1, for energy and muscle recovery
- Says it ships to all 50 states with discreet delivery from licensed pharmacy partners
Watch-outs
- Doesn't publish its legal operating entity, so accountability is hard to verify
- Pharmacy partners are described as licensed but none are named
- No terms-of-service page is posted, and FAQ answers load only via script
- Compounded semaglutide and tirzepatide only — no brand-name or oral options
- No LegitScript or third-party accreditation is shown on the site
Primary Clinic (Direct GLP)
What we like
- Direct Primary Care model integrates GLP-1 with continuous primary care — unlike most direct-to-consumer platforms
- GLP-1 at wholesale cost with no markup — semaglutide from $65/mo, tirzepatide from $110/mo (members only)
- Unlimited primary care visits, direct text access, and same-day care bundled in the $89/mo membership
- Routine labs and thousands of medications included in membership — no surprise bills
- Per-dose pricing shown publicly for all 8 dose tiers of both semaglutide and tirzepatide
- Publishes the FDA 503A compounded-medication disclaimer
Watch-outs
- 10 states only (WA, NM, AZ, UT, FL, DC, KS, OK, VA, GA) — limited vs 50-state platforms
- Membership required to access wholesale pricing — $89/mo adds ~$1,068/yr in fixed cost
- 503A pharmacy partners not named
- LegitScript certification not mentioned on the site
- Medical director and corporate legal entity not disclosed
- Compounded only — no brand-name Wegovy, Ozempic, Mounjaro, or Zepbound
- Refund policy not disclosed publicly
Our Verdict
Primary Clinic (Direct GLP) edges out 10rx with a higher overall score of 8.0/10 and is particularly strong for GLP-1 at wholesale cost inside a Direct Primary Care membership. 10rx remains a solid alternative, especially if you're looking for budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons.
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Related comparisons
Continue exploring 10rx and Primary Clinic (Direct GLP) head-to-heads in the same category.
- 10rx vs CoreAge Rx
- 10rx vs TrimRx
- 10rx vs Amazon One Medical
- Primary Clinic (Direct GLP) vs NovoCare Pharmacy
- Primary Clinic (Direct GLP) vs Vytora Health
- Primary Clinic (Direct GLP) vs Enhance MD
Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.