10rx vs Piper
An in-depth comparison of two leading GLP-1 Providers
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10rx
Best for budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-onsStarting at $99.67/mo
Piper
Best for mainstream telehealth GLP-1 accessStarting at $135/mo
Side-by-Side Comparison
| Feature | 10rx | Piper |
|---|---|---|
| Overall Score | 7.0/10 | ✓7.6/10 |
| Starting Price | ✓$99.67/mo | $135/mo |
| Editorial Rating | 3.5 ★ /5 | ✓3.8 ★ /5 |
| Features | ✓8 features | 3 features |
| States Available | 0 | ✓50 |
| Compounded | — | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
Pros & Cons
10rx
What we like
- Very low pricing — compounded semaglutide $99.67/month and tirzepatide $149.67/month
- Free online health quiz with board-certified telehealth doctors reviewing eligibility
- Offers NAD+ and sermorelin alongside GLP-1, for energy and muscle recovery
- Says it ships to all 50 states with discreet delivery from licensed pharmacy partners
Watch-outs
- Doesn't publish its legal operating entity, so accountability is hard to verify
- Pharmacy partners are described as licensed but none are named
- No terms-of-service page is posted, and FAQ answers load only via script
- Compounded semaglutide and tirzepatide only — no brand-name or oral options
- No LegitScript or third-party accreditation is shown on the site
Piper
What we like
- Aggressively low monthly pricing
- Both semaglutide and tirzepatide available
- Compounded GLP-1 access
Watch-outs
- Limited public information on program details
Our Verdict
Piper edges out 10rx with a higher overall score of 7.6/10 and is particularly strong for mainstream telehealth GLP-1 access. 10rx remains a solid alternative, especially if you're looking for budget-focused patients who want low-cost compounded GLP-1 with NAD+ and sermorelin add-ons.
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
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