Vytora Health vs Wisp
In our scoring, Vytora Health edges ahead overall (8.4 vs 7.1 out of 10).
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Key differences
- Price
- Vytora Health $179/mo for compounded semaglutide; Wisp $225/mo for oral compounded semaglutide (different medications, so not compared on price)
- Coverage
- Vytora Health 50 states + DC (Wisp doesn't publish a state list)
- Included
- Vytora Health: medication, clinician visits, shipping; Wisp: medication, shipping
Vytora Health
Best for compounded or brand-name GLP-1 with named pharmacy partners, 50 states
semaglutide
$179
Our score 8.4/10
Wisp
Best for branded injectables plus a sublingual semaglutide alternative
Oral compounded semaglutide
$225
Our score 7.1/10
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Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
Vytora Health
Wisp
Price
Semaglutide / month
$179/mo
Not listed
Tirzepatide / month
$249/mo
Not listed
Oral semaglutide / month
Not listed
$225/mo
Brand Zepbound / Mounjaro / month
$1,399/mo
Not listed
Coverage
State availability
50 states + DC
List not published
Oral option listed
Not listed
Yes
Brand-name access listed
Zepbound / Mounjaro
Not listed
Included in the price
Medication, clinician visits, shipping
Medication, shipping
Terms & safety
Price shown
Before intake
Before intake
Cancel anytime
Yes
Not disclosed
Minimum commitment
None on monthly plans; 3-month plans are billed every 3 months
Not disclosed
Refunds
'All sales are final' for prescription products; refund requests 'reviewed on a case-by-case basis'
Not disclosed
FDA warning letters
None on record
None on record
Provider facts checked
October 2026
August 2026
Every dose and plan: Vytora Health · Wisp
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose Vytora Health if…
- Lists compounded semaglutide, compounded tirzepatide and brand-name Zepbound / Mounjaro, which Wisp doesn't price
- Publishes its full state list (50 states + DC)
- Both compounded and brand-name options on one platform
What to weigh up
- Brand-name Mounjaro and Zepbound at $1,399/mo are priced at retail; manufacturer self-pay programs are often cheaper
- Compounded tirzepatide at $249/mo month-to-month is mid-market
Choose Wisp if…
- Lists oral compounded semaglutide, which Vytora Health doesn't price
- Broad GLP-1 menu — branded injectables (Wegovy, Zepbound, Saxenda) plus a compounded sublingual option
- LegitScript certified with named board-certified providers (Dr. Shannon Chatham DO, Andrea Sleeth WHNP-BC)
What to weigh up
- No published state list; confirm yours at signup
- Sublingual compounded semaglutide hasn't been tested in humans, per Wisp's own page — only the injectables have FDA efficacy data
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Vytora Health
8.4/10
Wisp
7.1/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
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From $139/mo
Get started →From $299/mo
Get started →SkinnyRx
Compounded semaglutide or tirzepatide with the consult and free overnight shipping in one price
Read full review →From $149.25/mo
Get started →Vytora Health vs Wisp: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.