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TrueMe vs NewSelf

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
TrueMe logo

TrueMe

7.2
★★★3.6/5

Best for: flat all-inclusive GLP-1 pricing with no membership fee, if you live in one of its six states

Visit TrueMe
VS
NewSelf logo

NewSelf

8.3
★★★★4.2/5

Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency

Visit NewSelf

TrueMe and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $159/mo, and NewSelf edges ahead overall (8.3 vs 7.2 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

TrueMe

Month-to-month (charged every 4 weeks)Compounded
$159/mo
semaglutide

Compounded semaglutide with added B vitamins. Price covers consultation, medication, shipping, supplies and ongoing provider support. A 3-month plan works out to $119/mo but is billed as a single $357 payment.

Month-to-month (charged every 4 weeks)Compounded
$189/mo
tirzepatide

Dual-action compounded tirzepatide with added B vitamins. A 3-month plan works out to $139/mo but is billed as a single $417 payment.

NewSelf

Semaglutide+ (best price)Compounded
$100/mo
semaglutide

All dosages same price

Semaglutide+ (regular)Compounded
$135/mo
semaglutide
Tirzepatide+ (best price)Compounded
$144/mo
tirzepatide

All dosages same price

Tirzepatide+ (regular)Compounded
$225/mo
tirzepatide

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What’s included

TrueMe

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Billed separately

Coaching

Not disclosed

NewSelf

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

TrueMe

7.2/10

Overall

NewSelf

8.3/10

Value25%

8.3A
vs
B
9.0

Effectiveness25%

7.5A
vs
B
8.0

User Experience15%

6.5A
vs
B
8.0

Trust & Safety15%

7.0A
vs
B
8.3

Accessibility10%

5.0A
vs
B
8.5

Support10%

7.0A
vs
B
7.9

Features & Coverage

FeatureTrueMeNewSelf
Starting Price$159/mo$100/mo
Features8 features6 features
States Available649
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About TrueMe

TrueMe is a cash-pay telehealth brand offering compounded semaglutide and tirzepatide with added B vitamins, alongside NAD+, sermorelin and glutathione. One flat price covers the consult, medication, shipping, supplies and ongoing provider support, with no membership fee and the same price at every dose. GLP-1 starts at $159 and GLP-1/GIP at $189, though both bill every four weeks rather than monthly. Service is currently limited to six states.

Read our full TrueMe review →

About NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.

Read our full NewSelf review →

Pros & Cons

TrueMe

What we like

  • One price covers consultation, medication, shipping, supplies and provider support, and the site states there are no separate membership fees
  • Same price at every dose, so the cost does not climb as a provider titrates the dose upward
  • Full pricing is published up front — no intake form is required before you can see what you will pay
  • Carries a genuine LegitScript-issued seal (ID 50205625) that resolves on LegitScript's own asset host
  • Names its telehealth platform (Telegra) and physician network (Strive), and the returns address names CarePoint Infusion Pharmacy in Stafford, Texas
  • Checkout states plainly that the order is not complete until the health questionnaire is finished
  • Says any charge is refunded if a provider decides treatment is not medically appropriate
  • Also publishes prices for NAD+ and sermorelin at $149/mo month-to-month, which most peptide sellers do not

Watch-outs

  • Serves only six states (AZ, CO, MO, PA, TX, WI), far narrower coverage than most national GLP-1 telehealth
  • Prices marketed per month are charged every 4 weeks at checkout — 13 charges a year, not 12
  • You pay before completing the medical intake, and approval is not guaranteed at the moment you are charged
  • The 3-month rates ($119 and $139/mo) are a single upfront charge of $357 or $417, not a lower monthly plan
  • A Featured In strip shows CNN, Fox News, Forbes, New York Times and NPR logos with no linked coverage
  • No clinicians or founders are named anywhere on the site, and the FAQ says the dispensing pharmacy may vary
  • The refund policy says TrueMe does not ship refrigerated products while the FAQ describes cold-chain shipping
  • Homepage lists five service states while every treatment page lists six, and unedited template copy remains

NewSelf

What we like

  • Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
  • All dosages at the same price — no price escalation as dose increases
  • LegitScript certified with 503A licensed pharmacies
  • Third-party potency, sterility, and endotoxicity testing
  • 48 states + Puerto Rico coverage
  • B12/B6 + Glycine enhanced formulations
  • No membership fees

Watch-outs

  • Not available in Mississippi and Louisiana
  • Compounded only — no brand-name options
  • Site also promotes AI health optimization and longevity (broader platform)

Our Verdict

Winner: NewSelf

NewSelf edges out TrueMe with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. TrueMe remains a solid alternative, especially if you're looking for flat all-inclusive GLP-1 pricing with no membership fee, if you live in one of its six states.

Choose TrueMe if…

You want flat all-inclusive GLP-1 pricing with no membership fee, if you live in one of its six states and a starting price around $159/mo.

Choose NewSelf if…

You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.

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7.6

Maximus

Men seeking compounded GLP-1 alongside testosterone optimization

8.0

Sesame Care

Brand-name GLP-1s (Wegovy, Zepbound) at LillyDirect/NovoCare cash prices — no compounding

6.9

Try Ageless

Lowest-tier compounded GLP-1 in injection, troche and sublingual forms

TrueMe vs NewSelf: FAQ

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