TelePeptide vs Enhance MD
An in-depth comparison of two leading GLP-1 Providers
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
TelePeptide
Best for: All-in compounded GLP-1 (sema/tirz, injectable + oral) from $169/mo; LegitScript-certified, 48 states
Visit TelePeptide →Enhance MD
Best for: lab-monitored compounded GLP-1 with mandatory video visit
Visit Enhance MD →TelePeptide and Enhance MD are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, TelePeptide starts lower at $169/mo versus $212/mo, and Enhance MD edges ahead overall (8.6 vs 8.2 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
TelePeptide
Verbatim from pricing page: Semaglutide Injectable $169/mo (annual prepay), $179/mo (6-month), $199/mo (monthly). All-inclusive — physician eval + Rx + medication + shipping.
Verbatim from pricing page: Tirzepatide Injectable $214/mo (annual prepay), $224/mo (6-month), $249/mo (monthly). All-inclusive — physician eval + Rx + medication + shipping.
Verbatim from pricing page: Semaglutide Dissolvable Tablet $199/mo (annual prepay), $209/mo (6-month), $229/mo (monthly). Oral sublingual formulation; all-inclusive.
Verbatim from pricing page: Tirzepatide Dissolvable Tablet $219/mo (annual prepay), $229/mo (6-month), $249/mo (monthly). Oral sublingual formulation; all-inclusive.
Enhance MD
What’s included
TelePeptide
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Enhance MD
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Not disclosed
Lab work
Included
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
TelePeptide
8.2/10
Enhance MD
8.6/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | TelePeptide | Enhance MD |
|---|---|---|
| Starting Price | ✓$169/mo | $212/mo |
| Features | ✓8 features | 6 features |
| States Available | Not disclosed | 39 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About TelePeptide
TelePeptide is a LegitScript-certified US direct-pay telehealth practice offering physician-supervised compounded GLP-1 therapy — semaglutide and tirzepatide — in injectable and oral dissolvable tablet formulations across 48 states and DC (excluding Alaska and Mississippi). Every all-inclusive plan covers the physician evaluation, prescription, medication, and shipping from a 503A-licensed compounding pharmacy, with no insurance required and no hidden fees. The practice is operated under MD Integrations, P.C.
Read our full TelePeptide review →About Enhance MD
Enhance MD pairs compounded semaglutide and tirzepatide with mandatory baseline metabolic labs at Quest Diagnostics and a synchronous video visit with a board-certified clinician — a more rigorous onboarding than the async-only compounded GLP-1 model most telehealth providers use. Three tiers (Core semaglutide, Advanced tirzepatide, Elite combined) plus aggressive intro pricing ($49 first month on Core).
Read our full Enhance MD review →Pros & Cons
TelePeptide
What we like
- LegitScript-certified (seal ID 49966407); 503A-licensed compounding pharmacies
- All-inclusive from $169/mo annual — physician eval + Rx + medication + shipping, no hidden fees
- Broadest formulation menu: injectable sema/tirz, oral dissolvable tablets, sema+naltrexone, microdose combos
- 24/7 care team messaging + regular check-ins + dosage adjustments included at every tier
- 48 states + DC coverage (excludes only AK + MS); no insurance required; cancel anytime
Watch-outs
- Compounded medications are not FDA-approved; no pharmacy partner named publicly
- Monthly billing costs more — $199/mo (monthly) vs $169/mo (annual) for semaglutide injectable; best rate requires annual prepay
- Labs not included in any plan
- Founder disclosed by first name only (Ahmed); no physician names or clinical leadership disclosed publicly
- Tirzepatide injectable at $249/mo (monthly billing) is above the compounded market average
Enhance MD
What we like
- Baseline and ongoing metabolic labs (CMP, lipids, TSH, HbA1c) at Quest every 6 months — rare for compounded GLP-1
- Mandatory video visit with a US-licensed MD or NP before your first prescription — not a pure questionnaire model
- Three tiers, including a combined semaglutide + tirzepatide Elite plan ($322/mo) for patients plateaued on one GLP-1
- Uses LegitScript-certified 503A pharmacies (Tru Meds Rx, Strive Pharmacy, Pharmacy Hub)
- Low first-month intro pricing: $49 Core, $99 Advanced, $189 Elite
- Unlimited clinician messaging and dose-adjustment support included
Watch-outs
- Compounded only — no FDA-approved Ozempic, Wegovy, Zepbound, or Mounjaro
- Not available in 10 states: AL, AR, GA, HI, LA, MS, MO, SC, TN, WV
- Mandatory lab work adds 5–10 days to onboarding vs async-only competitors
- No insurance accepted — cash pay, HSA/FSA eligible
- Intro pricing resets to full tier rate after 30 days — the $49/$99/$189 figures aren't ongoing cost
Our Verdict
Enhance MD edges out TelePeptide with a higher overall score of 8.6/10 and is particularly strong for lab-monitored compounded GLP-1 with mandatory video visit. TelePeptide remains a solid alternative, especially if you're looking for All-in compounded GLP-1 (sema/tirz, injectable + oral) from $169/mo; LegitScript-certified, 48 states.
Choose TelePeptide if…
You want All-in compounded GLP-1 (sema/tirz, injectable + oral) from $169/mo; LegitScript-certified, 48 states and a starting price around $169/mo.
Choose Enhance MD if…
You want lab-monitored compounded GLP-1 with mandatory video visit and a starting price around $212/mo.
Ready to start? Vetted GLP-1 providers
Vetted telehealth providers that prescribe GLP-1 online, ranked by our editorial score.
No insurance needed · vetted by our editors
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
Bodybuilding Health+
Fitness-brand compounded GLP-1 with hormone and performance programs
From $179/mo
Get started →Gala
Compounded GLP-1/GIP combo therapy on a yearly subscription with free shipping nationwide
From $149/mo
Get started →Trimi Health
Budget-conscious shoppers
From $99/mo
Get started →TelePeptide vs Enhance MD: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Related comparisons
Continue exploring TelePeptide and Enhance MD head-to-heads in the same category.
- TelePeptide vs CoreAge Rx
- TelePeptide vs Amazon One Medical
- TelePeptide vs NovoCare Pharmacy
- Enhance MD vs Vytora Health
- Enhance MD vs Noom Med
- Enhance MD vs Novi
Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.