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TelePeptide vs Enhance MD

An in-depth comparison of two leading GLP-1 Providers

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TelePeptide logo

TelePeptide

8.2
★★★★4.1

Best for: All-in compounded GLP-1 (sema/tirz, injectable + oral) from $169/mo; LegitScript-certified, 48 states

Visit TelePeptide
VS
Enhance MD logo

Enhance MD

8.6
★★★★4.3

Best for: lab-monitored compounded GLP-1 with mandatory video visit

Visit Enhance MD

TelePeptide and Enhance MD are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, TelePeptide starts lower at $169/mo versus $212/mo, and Enhance MD edges ahead overall (8.6 vs 8.2 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

TelePeptide

Starting doseCompounded
$169/mo
semaglutide

Verbatim from pricing page: Semaglutide Injectable $169/mo (annual prepay), $179/mo (6-month), $199/mo (monthly). All-inclusive — physician eval + Rx + medication + shipping.

Starting doseCompounded
$214/mo
tirzepatide

Verbatim from pricing page: Tirzepatide Injectable $214/mo (annual prepay), $224/mo (6-month), $249/mo (monthly). All-inclusive — physician eval + Rx + medication + shipping.

Starting dose (oral)Compounded
$199/mo
semaglutide

Verbatim from pricing page: Semaglutide Dissolvable Tablet $199/mo (annual prepay), $209/mo (6-month), $229/mo (monthly). Oral sublingual formulation; all-inclusive.

Starting dose (oral)Compounded
$219/mo
tirzepatide

Verbatim from pricing page: Tirzepatide Dissolvable Tablet $219/mo (annual prepay), $229/mo (6-month), $249/mo (monthly). Oral sublingual formulation; all-inclusive.

Enhance MD

GLP-1 CoreCompounded
$212$49/mo
Save 77% right now
semaglutide
GLP-1 AdvancedCompounded
$280$99/mo
Save 65% right now
tirzepatide
GLP-1 Elite (sema + tirz)Compounded
$322$189/mo
Save 41% right now
tirzepatide

What’s included

TelePeptide

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Enhance MD

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Not disclosed

Lab work

Included

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

TelePeptide

8.2/10

Overall

Enhance MD

8.6/10

Value25%

8.5A
vs
B
8.5

Effectiveness25%

7.5A
vs
B
8.5

User Experience15%

8.0A
vs
B
8.5

Trust & Safety15%

8.5A
vs
B
8.5

Accessibility10%

9.0A
vs
B
9.0

Support10%

8.5A
vs
B
9.0

Features & Coverage

FeatureTelePeptideEnhance MD
Starting Price$169/mo$212/mo
Features8 features6 features
States AvailableNot disclosed39
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About TelePeptide

TelePeptide is a LegitScript-certified US direct-pay telehealth practice offering physician-supervised compounded GLP-1 therapy — semaglutide and tirzepatide — in injectable and oral dissolvable tablet formulations across 48 states and DC (excluding Alaska and Mississippi). Every all-inclusive plan covers the physician evaluation, prescription, medication, and shipping from a 503A-licensed compounding pharmacy, with no insurance required and no hidden fees. The practice is operated under MD Integrations, P.C.

Read our full TelePeptide review →

About Enhance MD

Enhance MD pairs compounded semaglutide and tirzepatide with mandatory baseline metabolic labs at Quest Diagnostics and a synchronous video visit with a board-certified clinician — a more rigorous onboarding than the async-only compounded GLP-1 model most telehealth providers use. Three tiers (Core semaglutide, Advanced tirzepatide, Elite combined) plus aggressive intro pricing ($49 first month on Core).

Read our full Enhance MD review →

Pros & Cons

TelePeptide

What we like

  • LegitScript-certified (seal ID 49966407); 503A-licensed compounding pharmacies
  • All-inclusive from $169/mo annual — physician eval + Rx + medication + shipping, no hidden fees
  • Broadest formulation menu: injectable sema/tirz, oral dissolvable tablets, sema+naltrexone, microdose combos
  • 24/7 care team messaging + regular check-ins + dosage adjustments included at every tier
  • 48 states + DC coverage (excludes only AK + MS); no insurance required; cancel anytime

Watch-outs

  • Compounded medications are not FDA-approved; no pharmacy partner named publicly
  • Monthly billing costs more — $199/mo (monthly) vs $169/mo (annual) for semaglutide injectable; best rate requires annual prepay
  • Labs not included in any plan
  • Founder disclosed by first name only (Ahmed); no physician names or clinical leadership disclosed publicly
  • Tirzepatide injectable at $249/mo (monthly billing) is above the compounded market average

Enhance MD

What we like

  • Baseline and ongoing metabolic labs (CMP, lipids, TSH, HbA1c) at Quest every 6 months — rare for compounded GLP-1
  • Mandatory video visit with a US-licensed MD or NP before your first prescription — not a pure questionnaire model
  • Three tiers, including a combined semaglutide + tirzepatide Elite plan ($322/mo) for patients plateaued on one GLP-1
  • Uses LegitScript-certified 503A pharmacies (Tru Meds Rx, Strive Pharmacy, Pharmacy Hub)
  • Low first-month intro pricing: $49 Core, $99 Advanced, $189 Elite
  • Unlimited clinician messaging and dose-adjustment support included

Watch-outs

  • Compounded only — no FDA-approved Ozempic, Wegovy, Zepbound, or Mounjaro
  • Not available in 10 states: AL, AR, GA, HI, LA, MS, MO, SC, TN, WV
  • Mandatory lab work adds 5–10 days to onboarding vs async-only competitors
  • No insurance accepted — cash pay, HSA/FSA eligible
  • Intro pricing resets to full tier rate after 30 days — the $49/$99/$189 figures aren't ongoing cost

Our Verdict

Winner: Enhance MD

Enhance MD edges out TelePeptide with a higher overall score of 8.6/10 and is particularly strong for lab-monitored compounded GLP-1 with mandatory video visit. TelePeptide remains a solid alternative, especially if you're looking for All-in compounded GLP-1 (sema/tirz, injectable + oral) from $169/mo; LegitScript-certified, 48 states.

Choose TelePeptide if…

You want All-in compounded GLP-1 (sema/tirz, injectable + oral) from $169/mo; LegitScript-certified, 48 states and a starting price around $169/mo.

Choose Enhance MD if…

You want lab-monitored compounded GLP-1 with mandatory video visit and a starting price around $212/mo.

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