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PlexusDx vs EverSlim

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
PlexusDx logo

PlexusDx

7.0
★★★3.5/5

Best for: nationwide compounded GLP-1 with optional genetic-test personalization

Visit PlexusDx
VS

EverSlim

8.3
★★★★4.2/5

Best for: flat-price compounded glp-1 care shipped nationwide

Visit EverSlim

PlexusDx and EverSlim are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, EverSlim starts lower at $113/mo versus $129/mo, and EverSlim edges ahead overall (8.3 vs 7.0 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

PlexusDx

Microdose GLP-1 monthlyCompounded
$129/mo
semaglutide

'Microdose GLP-1 $129/mo All-Inclusive — small weekly dose, lower side effects, entry-level.'

Compounded semaglutide startingCompounded
$149/mo
semaglutide

'Semaglutide Starts at $149/mo All-Inclusive — weekly injection or daily oral.'

Compounded tirzepatide startingCompounded
$249/mo
tirzepatide

'Tirzepatide Starts at $249/mo All-Inclusive — dual-receptor.'

GLP-Squared — semaglutide + tirzepatide in one weekly injectionCompounded
$249/mo
tirzepatide

'PlexusDx Exclusive GLP-Squared — Semaglutide + Tirzepatide. Single weekly injection.' Priced the same as tirzepatide alone.

EverSlim

All doses (flat)Compounded
$113/mo
semaglutide

Flat monthly price; medication, provider visit, and shipping included

All doses (flat)Compounded
$136/mo
tirzepatide

Flat monthly price; dual-action GLP-1 and GIP

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What’s included

PlexusDx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Not disclosed

Lab work

Not disclosed

Coaching

Not disclosed

EverSlim

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

PlexusDx

7.0/10

Overall

EverSlim

8.3/10

Value25%

7.0A
vs
B
8.5

Effectiveness25%

7.0A
vs
B
8.0

User Experience15%

7.0A
vs
B
8.5

Trust & Safety15%

6.8A
vs
B
7.8

Accessibility10%

7.5A
vs
B
9.5

Support10%

6.5A
vs
B
7.5

Features & Coverage

FeaturePlexusDxEverSlim
Starting Price$129/mo$113/mo
Features8 features8 features
States Available5051
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About PlexusDx

PlexusDx (plexusdx.com) is a US GLP-1 telehealth platform offering compounded weight-loss medications with licensed providers in all 50 states. Programs include a microdose GLP-1 from $129/month, compounded semaglutide from $149/month, compounded tirzepatide from $249/month, and a combination GLP-Squared protocol. An independent US-licensed clinician reviews each patient via a state-licensed telehealth platform, and medications come from state-licensed pharmacies. PlexusDx is distinctive for an optional Precision Peptide genetic test (151 insights) discounted to $99 after a first order.

Read our full PlexusDx review →

About EverSlim

EverSlim is a US telehealth program offering doctor-prescribed, compounded GLP-1 weight-loss medication delivered to your door. It provides compounded semaglutide from 127 dollars a month and compounded tirzepatide from 183 dollars a month, a flat monthly price that includes the provider visit, prescription, and free shipping, with no insurance or membership required. Care is delivered by licensed US providers through the DrTelx medical group and filled by named LegitScript-approved US compounding pharmacies. Available in all 50 states and DC. Compounded meds are not FDA-approved.

Read our full EverSlim review →

Pros & Cons

PlexusDx

What we like

  • Licensed providers available in all 50 states
  • Range of options including low-cost microdose GLP-1 from $129/mo
  • Optional Precision Peptide genetic panel adds a personalization angle
  • Independent clinician review via state-licensed telehealth platform
  • Compounded medications from state-licensed pharmacies

Watch-outs

  • Compounded medications only; no FDA-approved brand options
  • Specific compounding pharmacies not named
  • Genetic-panel upsell may not add clinical value for everyone
  • Tirzepatide pricing from $249/mo is higher than budget rivals
  • No insurance accepted

EverSlim

What we like

  • Transparent flat pricing from 127 dollars a month for compounded semaglutide; medication, provider visit, and shipping included with no insurance.
  • Names its pharmacy partners (EPIQ Scripts, Foothills, Emerald) and DrTelx medical group; LegitScript-approved and NABP-accredited.
  • Available in all 50 states and DC, with asynchronous care in 44 states and live-visit access in the rest.
  • Offers both semaglutide and tirzepatide, plus care-team messaging between visits.

Watch-outs

  • Compounded medications are not FDA-approved, and no brand-name Wegovy, Ozempic, or Zepbound options are offered.
  • Site discloses that some imagery and content may be AI-generated and some ad figures are actors, not real clinicians.
  • Newer brand with limited independent, third-party review history.

Our Verdict

Winner: EverSlim

EverSlim edges out PlexusDx with a higher overall score of 8.3/10 and is particularly strong for flat-price compounded glp-1 care shipped nationwide. PlexusDx remains a solid alternative, especially if you're looking for nationwide compounded GLP-1 with optional genetic-test personalization.

Choose PlexusDx if…

You want nationwide compounded GLP-1 with optional genetic-test personalization and a starting price around $129/mo.

Choose EverSlim if…

You want flat-price compounded glp-1 care shipped nationwide and a starting price around $113/mo.

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8.0

Strut Health

Oral-lozenge compounded GLP-1 access

7.8

Yucca Health

Mainstream telehealth GLP-1 access

8.2

Gala

Compounded GLP-1/GIP combo on a yearly plan with free shipping

PlexusDx vs EverSlim: FAQ

EverSlim is cheaper. Its lowest ongoing monthly cash price is $113/mo, compared with $129/mo for PlexusDx. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.
EverSlim scores higher overall at 8.3/10 versus 7.0/10, and is particularly strong for flat-price compounded glp-1 care shipped nationwide. That said, PlexusDx is a better fit if you want nationwide compounded GLP-1 with optional genetic-test personalization.
EverSlim covers more — 51 states versus 50.
Neither PlexusDx nor EverSlim is currently an affiliate partner, so we earn no commission from either. We rank all providers editorially using the same six-dimension framework and disclose any commercial relationships.
For Semaglutide, EverSlim is cheaper at $113/mo versus $129/mo at PlexusDx.

Key terms, explained

New to GLP-1s? Tap any term for a quick, plain-English definition.

Continue exploring PlexusDx and EverSlim head-to-heads in the same category.

Or see the full category ranking.

Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.