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Optimized Health vs CoreAge Rx

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Optimized Health logo

Optimized Health

7.3
★★★3.7/5

Best for: MO/IA/KS/UT/WA patients wanting lab-guided compounded GLP-1

Visit Optimized Health
VS
CoreAge Rx logo

CoreAge Rx

8.3
★★★★4.2/5

Best for: best overall value

Visit CoreAge Rx

Optimized Health and CoreAge Rx are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, CoreAge Rx starts lower at $99/mo versus $200/mo, and CoreAge Rx edges ahead overall (8.3 vs 7.3 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Optimized Health

Starting doseCompounded
$200/mo
semaglutide
Starting doseCompounded
$250/mo
tirzepatide

CoreAge Rx

Injectable, monthly auto-refill (flat across all dosages)Compounded
$99/mo
semaglutide

Re-verified 2026-08-05: homepage + Preventive Longevity section both show "Semaglutide — Starting at $99/mo", "Same price at every dose"; supersedes stale tiered pricing captured 2026-06-05.

Injectable, monthly auto-refill (flat across all dosages)Compounded
$149/mo
tirzepatide

Re-verified 2026-08-05: homepage GLP-1 hero + Preventive Longevity section both show "Tirzepatide — Starting at $149/mo", "Same price at every dose"; supersedes stale tiered pricing captured 2026-06-05.

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What’s included

Optimized Health

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Not disclosed

Lab work

Not disclosed

Coaching

Not disclosed

CoreAge Rx

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Optimized Health

7.3/10

Overall

CoreAge Rx

8.3/10

Value25%

7.5A
vs
B
8.5

Effectiveness25%

7.0A
vs
B
8.5

User Experience15%

7.0A
vs
B
8.5

Trust & Safety15%

7.8A
vs
B
7.8

Accessibility10%

7.0A
vs
B
8.0

Support10%

7.4A
vs
B
8.4

Features & Coverage

FeatureOptimized HealthCoreAge Rx
Starting Price$200/mo$99/mo
Features8 features6 features
States Available550
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted✓ Yes
FDA WarningsNoneNone

About Optimized Health

Optimized Health is a concierge medical weight loss and hormone clinic offering clinician-supervised GLP-1 programs with compounded semaglutide and tirzepatide, plus oral options like phentermine. Care is delivered via telehealth in Missouri, Iowa, Kansas, Utah, and Washington, or in person in Joplin, MO. Pricing is published openly: semaglutide from $200/month and tirzepatide from $250/month, with lab panels included, meds shipped to the door, and receipts for HSA/FSA reimbursement. The clinic is LegitScript certified and led by Mathew Hammons, PA-C, with over a decade in obesity medicine.

Read our full Optimized Health review →

About CoreAge Rx

CoreAge Rx offers LegitScript-verified compounded semaglutide and tirzepatide with free 2-day shipping to all 50 states. Backed by licensed physicians and 24/7 support, it delivers the most competitive pricing in the compounded GLP-1 space.

Read our full CoreAge Rx review →

Pros & Cons

Optimized Health

What we like

  • Fully transparent pricing published on the website
  • Semaglutide from $200/mo and tirzepatide from $250/mo
  • Lab panels included with clinician-supervised dosing
  • LegitScript certified clinic
  • Lead PA-C with over a decade in obesity medicine
  • HSA/FSA receipts provided and medications shipped home

Watch-outs

  • Telehealth limited to MO, IA, KS, UT, and WA
  • Compounded GLP-1 only, not brand-name
  • No insurance billing (cash-pay)
  • PA-led rather than MD/DO-led

CoreAge Rx

What we like

  • LegitScript certified — rigorous pharmacy standards
  • Free 2-day shipping nationwide
  • Both semaglutide and tirzepatide available
  • Lowest per-month pricing in the compounded segment
  • 24/7 support team
  • All 50 states covered

Watch-outs

  • Compounded only — no brand-name Ozempic or Wegovy
  • Newer brand with fewer independent reviews than legacy players

Our Verdict

Winner: CoreAge Rx

CoreAge Rx edges out Optimized Health with a higher overall score of 8.3/10 and is particularly strong for best overall value. Optimized Health remains a solid alternative, especially if you're looking for MO/IA/KS/UT/WA patients wanting lab-guided compounded GLP-1.

Choose Optimized Health if…

You want MO/IA/KS/UT/WA patients wanting lab-guided compounded GLP-1 and a starting price around $200/mo.

Choose CoreAge Rx if…

You want best overall value and a starting price around $99/mo.

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8.0

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Oral-lozenge compounded GLP-1 access

7.8

Yucca Health

Mainstream telehealth GLP-1 access

7.7

TrimRx

Best overall value

Optimized Health vs CoreAge Rx: FAQ

CoreAge Rx is cheaper. Its lowest ongoing monthly cash price is $99/mo, compared with $200/mo for Optimized Health. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.
CoreAge Rx scores higher overall at 8.3/10 versus 7.3/10, and is particularly strong for best overall value. That said, Optimized Health is a better fit if you want MO/IA/KS/UT/WA patients wanting lab-guided compounded GLP-1.
CoreAge Rx covers more — 50 states versus 5.
CoreAge Rx is an affiliate partner (we may earn a commission on sign-ups through our links); Optimized Health is not. Either way, we rank providers editorially with the same scoring framework and disclose every partnership — being a partner does not buy a higher score.
For Semaglutide, CoreAge Rx is cheaper at $99/mo versus $200/mo at Optimized Health.

Key terms, explained

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Continue exploring Optimized Health and CoreAge Rx head-to-heads in the same category.

Or see the full category ranking.

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