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Onyx Weight Loss vs Collective

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
Onyx Weight Loss logo

Onyx Weight Loss

6.2
★★★☆☆3.1/5

Best for: NP-led GLP-1 telehealth in 8 states; sema $228/mo or tirz $280/mo, all-in

Visit Onyx Weight Loss →
VS
Collective logo

Collective

8.3
★★★★☆4.2/5

Best for: the lowest flat medication price if you can absorb an annual membership fee

Visit Collective →

Onyx Weight Loss and Collective are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Collective starts lower at $59/mo versus $99/mo, and Collective edges ahead overall (8.3 vs 6.2 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

Onyx Weight Loss

Starting doseCompounded
$228/mo
semaglutide

Verbatim: 'Starting at $228/month' (GLP-1 Agonist plan). Includes medication and supplies shipped to home. Entry tier only; higher-dose pricing not disclosed.

Starting doseCompounded
$280/mo
tirzepatide

Verbatim: 'Starting at $280/month' (GLP-1/GIP Agonist plan). Includes medication and supplies. Entry tier only; specific drug name inferred from GLP-1/GIP dual agonist designation.

MicrodoseCompounded
$99/mo
semaglutide

Verbatim: '$99/MONTH' (GLP-1 Microdosing plan). Low-dose gradual-start option.

Collective

Any dose (flat price)Compounded
$59/mo
semaglutide

Verbatim: 'Compounded Semaglutide: $59/month. Same price, every dose. Cancel anytime.' ⛔ EXCLUDES the required membership — the site states 'What does it cost? $59/month + $199 annual membership.' First-year total is $907 ($75.58/mo equivalent).

Any dose (flat price)Compounded
$69/mo
tirzepatide

Verbatim: 'Compounded Tirzepatide: $69/month. Same price, any dose.' ⛔ EXCLUDES the required membership — 'The cost is $69/month + $199 annual membership.' First-year total is $1,027 ($85.58/mo equivalent).

Required annual membership (subscription, medication billed separately)membership subscription
$199/mo

Verbatim: 'Requires Collective membership: 21 day free trial, then a low annual $199 membership fee. No recurring monthly membership charges.' Charged yearly, not monthly. Terms of Use: 'all membership fees are non-refundable, and partial-period refunds are not provided.'

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What’s included

Onyx Weight Loss

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Collective

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

Onyx Weight Loss

6.2/10

Overall

Collective

8.3/10

Value25%

7.0A
vs
B
9.4

Effectiveness25%

6.5A
vs
B
8.2

User Experience15%

5.5A
vs
B
8.0

Trust & Safety15%

5.8A
vs
B
7.2

Accessibility10%

4.0A
vs
B
7.4

Support10%

7.4A
vs
B
8.4

Features & Coverage

FeatureOnyx Weight LossCollective
Starting Price$99/mo✓$59/mo
Features✓8 features3 features
States Available8Not disclosed
Compounded✓ Yes✓ Yes
Brand Name——
FSA/HSA Accepted——
FDA WarningsNoneNone

About Onyx Weight Loss

Onyx Weight Loss is a nurse-practitioner-led telehealth clinic based in Mooresville, NC, offering GLP-1 and GLP-1/GIP weight-loss medications alongside peptides and HRT across 8 states. Founded by Tasha Vangile FNP-C and Madalyn Vangile RN, plans start at $228/month for GLP-1 (semaglutide-type) and $280/month for GLP-1/GIP (tirzepatide-type), with medication and supplies shipped home via Strive Pharmacy partner. A $99/month GLP-1 microdosing option is also available for a gradual-titration start.

Read our full Onyx Weight Loss review →

About Collective

Collective (collective.org) is a membership-based telehealth platform from the founder of Thrive Market, selling compounded semaglutide and tirzepatide at a flat price on every dose. Medication is billed separately from a required annual membership, and the program bundles unlimited clinician messaging, dietitian access and express cold shipping.

Read our full Collective review →

Pros & Cons

Onyx Weight Loss

What we like

  • Competitive entry pricing: semaglutide from $228/mo and tirzepatide from $280/mo with medication + supplies included
  • Nurse-practitioner-led care: founder Tasha Vangile FNP-C (20+ years) and Stephanie Robison APRN-CNP (27 years experience)
  • Low-cost $99/mo GLP-1 microdosing option for patients who prefer a gradual titration start
  • Strive Pharmacy partnership implies compounded 503A-quality supply chain from a known pharmacy
  • Multi-modal clinic: GLP-1 + peptides + HRT + nutrition coaching available under one provider team

Watch-outs

  • Only 8 states (NC, CO, ME, VT, VA, IA, NH, PA) — excludes the majority of the US
  • No LegitScript certification; credentialing evidence limited to local 2025 Best of Iredell award
  • Specific drug names (semaglutide/tirzepatide) never stated on website; compounded status inferred, not disclosed
  • Labs not included or mentioned; no baseline bloodwork protocol published
  • Pricing shown as 'Starting at' with no dose-escalation tier pricing disclosed publicly

Collective

What we like

  • The lowest published compounded GLP-1 medication prices we track — $59/month semaglutide and $69/month tirzepatide
  • Flat pricing at every dose, so titrating up does not raise the bill
  • Unlimited clinician messaging and registered-dietitian access are included rather than upsold
  • 21-day free trial on the membership before the annual fee is charged

Watch-outs

  • The advertised $59 and $69 exclude a mandatory $199 annual membership — the real first-year cost is $907 and $1,027
  • Membership fees are non-refundable and no partial-period refunds are given
  • Compounding pharmacies are described only as 'independent, third-party licensed pharmacies' and are never named
  • State availability is not published on the marketing site

Our Verdict

Winner: Collective

Collective edges out Onyx Weight Loss with a higher overall score of 8.3/10 and is particularly strong for the lowest flat medication price if you can absorb an annual membership fee. Onyx Weight Loss remains a solid alternative, especially if you're looking for NP-led GLP-1 telehealth in 8 states; sema $228/mo or tirz $280/mo, all-in.

Choose Onyx Weight Loss if…

You want NP-led GLP-1 telehealth in 8 states; sema $228/mo or tirz $280/mo, all-in and a starting price around $99/mo.

Choose Collective if…

You want the lowest flat medication price if you can absorb an annual membership fee and a starting price around $59/mo.

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Onyx Weight Loss vs Collective: FAQ

Collective is cheaper. Its lowest ongoing monthly cash price is $59/mo, compared with $99/mo for Onyx Weight Loss. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.
Collective scores higher overall at 8.3/10 versus 6.2/10, and is particularly strong for the lowest flat medication price if you can absorb an annual membership fee. That said, Onyx Weight Loss is a better fit if you want NP-led GLP-1 telehealth in 8 states; sema $228/mo or tirz $280/mo, all-in.
Onyx Weight Loss lists availability in 8 states, while Collective's state list is not publicly listed.
Collective is an affiliate partner (we may earn a commission on sign-ups through our links); Onyx Weight Loss is not. Either way, we rank providers editorially with the same scoring framework and disclose every partnership — being a partner does not buy a higher score.
For Semaglutide, Collective is cheaper at $59/mo versus $99/mo at Onyx Weight Loss.

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Continue exploring Onyx Weight Loss and Collective head-to-heads in the same category.

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