NewSelf vs TrueMe
An in-depth comparison of two leading GLP-1 Providers
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
NewSelf
Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency
Visit NewSelf →
TrueMe
Best for: flat all-inclusive GLP-1 pricing with no membership fee, if you live in one of its six states
Visit TrueMe →NewSelf and TrueMe are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $159/mo, and NewSelf edges ahead overall (8.3 vs 7.2 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
NewSelf
All dosages same price
All dosages same price
TrueMe
Compounded semaglutide with added B vitamins. Price covers consultation, medication, shipping, supplies and ongoing provider support. A 3-month plan works out to $119/mo but is billed as a single $357 payment.
Dual-action compounded tirzepatide with added B vitamins. A 3-month plan works out to $139/mo but is billed as a single $417 payment.
Get alerted when GLP-1 prices drop
Join the GLP-1 price-watch list — we re-verify 400+ providers' prices on their own sites and email you when tracked prices move.
What’s included
NewSelf
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
TrueMe
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Billed separately
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
NewSelf
8.3/10
TrueMe
7.2/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | NewSelf | TrueMe |
|---|---|---|
| Starting Price | ✓$100/mo | $159/mo |
| Features | 6 features | ✓8 features |
| States Available | ✓49 | 6 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About NewSelf
NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.
Read our full NewSelf review →About TrueMe
TrueMe is a cash-pay telehealth brand offering compounded semaglutide and tirzepatide with added B vitamins, alongside NAD+, sermorelin and glutathione. One flat price covers the consult, medication, shipping, supplies and ongoing provider support, with no membership fee and the same price at every dose. GLP-1 starts at $159 and GLP-1/GIP at $189, though both bill every four weeks rather than monthly. Service is currently limited to six states.
Read our full TrueMe review →Pros & Cons
NewSelf
What we like
- Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
- All dosages at the same price — no price escalation as dose increases
- LegitScript certified with 503A licensed pharmacies
- Third-party potency, sterility, and endotoxicity testing
- 48 states + Puerto Rico coverage
- B12/B6 + Glycine enhanced formulations
- No membership fees
Watch-outs
- Not available in Mississippi and Louisiana
- Compounded only — no brand-name options
- Site also promotes AI health optimization and longevity (broader platform)
TrueMe
What we like
- One price covers consultation, medication, shipping, supplies and provider support, and the site states there are no separate membership fees
- Same price at every dose, so the cost does not climb as a provider titrates the dose upward
- Full pricing is published up front — no intake form is required before you can see what you will pay
- Carries a genuine LegitScript-issued seal (ID 50205625) that resolves on LegitScript's own asset host
- Names its telehealth platform (Telegra) and physician network (Strive), and the returns address names CarePoint Infusion Pharmacy in Stafford, Texas
- Checkout states plainly that the order is not complete until the health questionnaire is finished
- Says any charge is refunded if a provider decides treatment is not medically appropriate
- Also publishes prices for NAD+ and sermorelin at $149/mo month-to-month, which most peptide sellers do not
Watch-outs
- Serves only six states (AZ, CO, MO, PA, TX, WI), far narrower coverage than most national GLP-1 telehealth
- Prices marketed per month are charged every 4 weeks at checkout — 13 charges a year, not 12
- You pay before completing the medical intake, and approval is not guaranteed at the moment you are charged
- The 3-month rates ($119 and $139/mo) are a single upfront charge of $357 or $417, not a lower monthly plan
- A Featured In strip shows CNN, Fox News, Forbes, New York Times and NPR logos with no linked coverage
- No clinicians or founders are named anywhere on the site, and the FAQ says the dispensing pharmacy may vary
- The refund policy says TrueMe does not ship refrigerated products while the FAQ describes cold-chain shipping
- Homepage lists five service states while every treatment page lists six, and unedited template copy remains
Our Verdict
NewSelf edges out TrueMe with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. TrueMe remains a solid alternative, especially if you're looking for flat all-inclusive GLP-1 pricing with no membership fee, if you live in one of its six states.
Choose NewSelf if…
You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.
Choose TrueMe if…
You want flat all-inclusive GLP-1 pricing with no membership fee, if you live in one of its six states and a starting price around $159/mo.
Ready to start? Vetted GLP-1 providers
Vetted telehealth providers that prescribe GLP-1 online.
No insurance needed · vetted by our editors
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
Direct Meds
Listed for transparent disclosure — see FDA warning and BBB complaint pattern before considering
From $249/mo
Get started →Maximus
Men seeking compounded GLP-1 alongside testosterone optimization
From $199.99/mo
Get started →Sesame Care
Brand-name GLP-1s (Wegovy, Zepbound) at LillyDirect/NovoCare cash prices — no compounding
From $25/mo
Get started →NewSelf vs TrueMe: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Related comparisons
Continue exploring NewSelf and TrueMe head-to-heads in the same category.
- NewSelf vs Amazon One Medical
- NewSelf vs Vytora Health
- NewSelf vs CoreAge Rx
- TrueMe vs EverSlim
- TrueMe vs Found
- TrueMe vs Elara Health and Wellness
Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.