LunaRx vs Enhance MD
An in-depth comparison of two leading GLP-1 Providers
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LunaRx
Best for: adults who want a GLP-1 program with muscle-protective peptides and a built-in off-ramp taper
Visit LunaRx →
Enhance MD
Best for: lab-monitored compounded GLP-1 with mandatory video visit
Visit Enhance MD →LunaRx and Enhance MD are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, LunaRx starts lower at $199/mo versus $212/mo, and Enhance MD edges ahead overall (8.6 vs 7.2 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
LunaRx
Published headline is "from $199/mo" for the entry Foundation stack (compounded semaglutide + muscle-protective peptides). Specific tier and tirzepatide pricing are confirmed only after a provider review; no per-dose price list is published.
Enhance MD
What’s included
LunaRx
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Enhance MD
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Not disclosed
Lab work
Included
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
LunaRx
7.2/10
Enhance MD
8.6/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | LunaRx | Enhance MD |
|---|---|---|
| Starting Price | ✓$199/mo | $212/mo |
| Features | ✓8 features | 6 features |
| States Available | Not disclosed | 39 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About LunaRx
LunaRx is a bilingual (English/Spanish) telehealth practice from LunaRx LLC built around "metabolic recomposition" — compounded GLP-1 therapy paired with muscle-protective peptides and a structured off-ramp taper, rather than an indefinite prescription. Programs start at $199/month; specific tier and tirzepatide pricing are confirmed only after a physician review. Care is physician-directed through an independent medical group (CareNexus Clinic PC), with $0 charged if you are not approved. Compounded medications are not FDA-approved.
Read our full LunaRx review →About Enhance MD
Enhance MD pairs compounded semaglutide and tirzepatide with mandatory baseline metabolic labs at Quest Diagnostics and a synchronous video visit with a board-certified clinician — a more rigorous onboarding than the async-only compounded GLP-1 model most telehealth providers use. Three tiers (Core semaglutide, Advanced tirzepatide, Elite combined) plus aggressive intro pricing ($49 first month on Core).
Read our full Enhance MD review →Pros & Cons
LunaRx
What we like
- Pairs GLP-1 with muscle-protective peptides (e.g., CJC-1295/Ipamorelin, NAD+) to defend lean mass during fat loss
- Structured, physician-directed off-ramp taper with GI-reset support instead of an indefinite prescription
- Bilingual care in English and Spanish across intake, messaging, and consults
- Care directed through a named independent medical group (CareNexus Clinic PC); $0 charged if you are not approved
- Published clinical support hours (Mon–Fri, CT) with phone, email, and secure messaging; cancel anytime
- 503A compounded medications prepared in the USA and shipped discreetly to your door
Watch-outs
- Only a "from $199/mo" starting price is published; tirzepatide and per-tier pricing are confirmed only after a provider review
- Compounding pharmacy partners are not named on the site — a transparency gap
- No LegitScript or PCAB verification is displayed
- States served are not published; the site claims "telehealth nationwide" but the Terms limit service to states where LunaRx is licensed
- Compounded medications are not FDA-approved (the site discloses this)
- No refunds once medication is dispensed; order cancellations are only accepted within 24 hours
- New brand with no independent Trustpilot or third-party rating; on-site testimonials only
Enhance MD
What we like
- Baseline and ongoing metabolic labs (CMP, lipids, TSH, HbA1c) at Quest every 6 months — rare for compounded GLP-1
- Mandatory video visit with a US-licensed MD or NP before your first prescription — not a pure questionnaire model
- Three tiers, including a combined semaglutide + tirzepatide Elite plan ($322/mo) for patients plateaued on one GLP-1
- Uses LegitScript-certified 503A pharmacies (Tru Meds Rx, Strive Pharmacy, Pharmacy Hub)
- Low first-month intro pricing: $49 Core, $99 Advanced, $189 Elite
- Unlimited clinician messaging and dose-adjustment support included
Watch-outs
- Compounded only — no FDA-approved Ozempic, Wegovy, Zepbound, or Mounjaro
- Not available in 10 states: AL, AR, GA, HI, LA, MS, MO, SC, TN, WV
- Mandatory lab work adds 5–10 days to onboarding vs async-only competitors
- No insurance accepted — cash pay, HSA/FSA eligible
- Intro pricing resets to full tier rate after 30 days — the $49/$99/$189 figures aren't ongoing cost
Our Verdict
Enhance MD edges out LunaRx with a higher overall score of 8.6/10 and is particularly strong for lab-monitored compounded GLP-1 with mandatory video visit. LunaRx remains a solid alternative, especially if you're looking for adults who want a GLP-1 program with muscle-protective peptides and a built-in off-ramp taper.
Choose LunaRx if…
You want adults who want a GLP-1 program with muscle-protective peptides and a built-in off-ramp taper and a starting price around $199/mo.
Choose Enhance MD if…
You want lab-monitored compounded GLP-1 with mandatory video visit and a starting price around $212/mo.
Ready to start? Vetted GLP-1 providers
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Get started →LunaRx vs Enhance MD: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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