Immortals vs Enhance MD
An in-depth comparison of two leading GLP-1 Providers
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Immortals
Best for: Bryan Johnson's longevity telehealth: compounded sema/tirz microdose injections from $167/mo
Visit Immortals →
Enhance MD
Best for: lab-monitored compounded GLP-1 with mandatory video visit
Visit Enhance MD →Immortals and Enhance MD are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Immortals starts lower at $167/mo versus $212/mo, and Enhance MD edges ahead overall (8.6 vs 7.5 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
Immortals
Verbatim from product page: 'From $167/mo*'. Promotional price (regular $245/month). Semaglutide/Glycine/B12 compounded formulation. Quarterly billing — $501 billed upfront for 3-month commitment. No added fees beyond the subscription.
Verbatim from product page: 'From $180/mo*'. Promotional price (regular $265/month). Tirzepatide/Glycine/B12 compounded formulation. Quarterly billing — $540 billed upfront for 3-month commitment. No added fees beyond the subscription.
Enhance MD
What’s included
Immortals
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Enhance MD
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Not disclosed
Lab work
Included
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Immortals
7.5/10
Enhance MD
8.6/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Immortals | Enhance MD |
|---|---|---|
| Starting Price | ✓$167/mo | $212/mo |
| Features | ✓8 features | 6 features |
| States Available | Not disclosed | 39 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About Immortals
Immortals is a LegitScript-certified longevity telehealth platform founded by Bryan Johnson, offering compounded semaglutide (Semaglutide/Glycine/B12) and tirzepatide (Tirzepatide/Glycine/B12) as microdose weekly injections. Every subscription includes physician review within 72 hours, prescription fulfillment from licensed U.S. pharmacies, discreet shipping, and unlimited provider messaging for 12 months. Semaglutide starts at $167/month and tirzepatide at $180/month (promotional, billed quarterly). HSA/FSA reimbursable; no insurance required.
Read our full Immortals review →About Enhance MD
Enhance MD pairs compounded semaglutide and tirzepatide with mandatory baseline metabolic labs at Quest Diagnostics and a synchronous video visit with a board-certified clinician — a more rigorous onboarding than the async-only compounded GLP-1 model most telehealth providers use. Three tiers (Core semaglutide, Advanced tirzepatide, Elite combined) plus aggressive intro pricing ($49 first month on Core).
Read our full Enhance MD review →Pros & Cons
Immortals
What we like
- LegitScript certified (ID 50458743) with board-certified U.S. physician review within 72 hours
- Physician consult + prescription bundled in price — 'You pay for treatment. That's it' with no added fees
- Competitive pricing: semaglutide microdose from $167/month, tirzepatide from $180/month (promotional)
- Unlimited provider messaging for 12 months included; video consults available
- Founded by Bryan Johnson and Kate Tolo; clinical lead Dr. Carl Seger, M.D. (preventive/longevity medicine)
Watch-outs
- Microdose framing uses sub-clinical doses — lower weight-loss efficacy than standard GLP-1 protocols
- Quarterly commitment only — 3-month minimum, paid upfront ($501–$540/quarter); no monthly flexibility
- State availability not publicly listed; 'eligible U.S. states' with no specific state list
- Labs not included; baseline bloodwork protocol not disclosed on any public page
- Compounding pharmacy not named; no 503A/503B accreditation details disclosed
Enhance MD
What we like
- Baseline and ongoing metabolic labs (CMP, lipids, TSH, HbA1c) at Quest every 6 months — rare for compounded GLP-1
- Mandatory video visit with a US-licensed MD or NP before your first prescription — not a pure questionnaire model
- Three tiers, including a combined semaglutide + tirzepatide Elite plan ($322/mo) for patients plateaued on one GLP-1
- Uses LegitScript-certified 503A pharmacies (Tru Meds Rx, Strive Pharmacy, Pharmacy Hub)
- Low first-month intro pricing: $49 Core, $99 Advanced, $189 Elite
- Unlimited clinician messaging and dose-adjustment support included
Watch-outs
- Compounded only — no FDA-approved Ozempic, Wegovy, Zepbound, or Mounjaro
- Not available in 10 states: AL, AR, GA, HI, LA, MS, MO, SC, TN, WV
- Mandatory lab work adds 5–10 days to onboarding vs async-only competitors
- No insurance accepted — cash pay, HSA/FSA eligible
- Intro pricing resets to full tier rate after 30 days — the $49/$99/$189 figures aren't ongoing cost
Our Verdict
Enhance MD edges out Immortals with a higher overall score of 8.6/10 and is particularly strong for lab-monitored compounded GLP-1 with mandatory video visit. Immortals remains a solid alternative, especially if you're looking for Bryan Johnson's longevity telehealth: compounded sema/tirz microdose injections from $167/mo.
Choose Immortals if…
You want Bryan Johnson's longevity telehealth: compounded sema/tirz microdose injections from $167/mo and a starting price around $167/mo.
Choose Enhance MD if…
You want lab-monitored compounded GLP-1 with mandatory video visit and a starting price around $212/mo.
Ready to start? Vetted GLP-1 providers
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Embody
Lowest first-month entry pricing on compounded GLP-1s
From $99/mo
Get started →TrimRx
Best overall value
From $179/mo
Get started →Telos Rx
Needle-free and microdosed compounded GLP-1 options with lab-monitored care
From $49/mo
Get started →Immortals vs Enhance MD: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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