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HydraMed vs NewSelf

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
HydraMed logo

HydraMed

6.5
★★★☆☆3.3/5

Best for: patients wanting all-in pricing with a single intake fee

Visit HydraMed
VS
NewSelf logo

NewSelf

8.3
★★★★4.2/5

Best for: lowest-cost compounded GLP-1 with pharmacy quality transparency

Visit NewSelf

HydraMed and NewSelf are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, NewSelf starts lower at $100/mo versus $179/mo, and NewSelf edges ahead overall (8.3 vs 6.5 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

HydraMed

0.25mgCompounded
$179/mo
semaglutide
1mgCompounded
$249/mo
semaglutide
2.5mgCompounded
$319/mo
tirzepatide

NewSelf

Semaglutide+ (best price)Compounded
$100/mo
semaglutide

All dosages same price

Semaglutide+ (regular)Compounded
$135/mo
semaglutide
Tirzepatide+ (best price)Compounded
$144/mo
tirzepatide

All dosages same price

Tirzepatide+ (regular)Compounded
$225/mo
tirzepatide

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What’s included

HydraMed

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Included

NewSelf

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

HydraMed

6.5/10

Overall

NewSelf

8.3/10

Value25%

6.5A
vs
B
9.0

Effectiveness25%

8.0A
vs
B
8.0

User Experience15%

6.5A
vs
B
8.0

Trust & Safety15%

4.5A
vs
B
8.3

Accessibility10%

4.5A
vs
B
8.5

Support10%

7.5A
vs
B
7.9

Features & Coverage

FeatureHydraMedNewSelf
Starting Price$179/mo$100/mo
Features6 features6 features
States Available1149
Compounded✓ Yes✓ Yes
Brand Name
FSA/HSA Accepted
FDA WarningsNoneNone

About HydraMed

HydraMed is a nationwide telehealth platform offering compounded semaglutide, tirzepatide, and a broader peptide menu including PT-141, GHK-Cu, and NAD+ in injection, nasal, and topical forms. All-inclusive monthly pricing covers prescription and supplies, free shipping, and a quick medical questionnaire intake. Compounding is performed at a US FDA-registered pharmacy. Also offers mobile IV services in CO, FL, TN, and WY.

Read our full HydraMed review →

About NewSelf

NewSelf offers compounded semaglutide+ (with B12/Glycine, from $99.97/mo) and compounded tirzepatide+ (with B6/Glycine, from $144.49/mo). LegitScript certified. Available in 48 states + Puerto Rico. Uses 503A licensed pharmacies with third-party testing.

Read our full NewSelf review →

Pros & Cons

HydraMed

What we like

  • All-inclusive pricing with no add-ons
  • Free shipping
  • US FDA-registered compounding pharmacy
  • Quick intake process

Watch-outs

  • Wide peptide menu beyond GLP-1s — patients should stay focused on FDA-approved indications
  • Trust score moderate pending more independent verification

NewSelf

What we like

  • Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
  • All dosages at the same price — no price escalation as dose increases
  • LegitScript certified with 503A licensed pharmacies
  • Third-party potency, sterility, and endotoxicity testing
  • 48 states + Puerto Rico coverage
  • B12/B6 + Glycine enhanced formulations
  • No membership fees

Watch-outs

  • Not available in Mississippi and Louisiana
  • Compounded only — no brand-name options
  • Site also promotes AI health optimization and longevity (broader platform)

Our Verdict

Winner: NewSelf

NewSelf edges out HydraMed with a higher overall score of 8.3/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. HydraMed remains a solid alternative, especially if you're looking for patients wanting all-in pricing with a single intake fee.

Choose HydraMed if…

You want patients wanting all-in pricing with a single intake fee and a starting price around $179/mo.

Choose NewSelf if…

You want lowest-cost compounded GLP-1 with pharmacy quality transparency and a starting price around $100/mo.

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8.0

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Oral-lozenge compounded GLP-1 access

7.8

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Mainstream telehealth GLP-1 access

HydraMed vs NewSelf: FAQ

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