He & She MD vs TrimRx
An in-depth comparison of two leading GLP-1 Providers
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He & She MD
Best for Transparent low intro-priced GLP-1 (injectable, oral, or microdose) with brand-name accessStarting at $99/mo
TrimRx
Best for best overall valueStarting at $199/mo
Side-by-Side Comparison
| Feature | He & She MD | TrimRx |
|---|---|---|
| Overall Score | 7.4/10 | ✓9.0/10 |
| Starting Price | ✓$99/mo | $199/mo |
| Editorial Rating | 3.7 ★ /5 | ✓4.5 ★ /5 |
| Features | ✓8 features | 3 features |
| States Available | ✓50 | 0 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
Pros & Cons
He & She MD
Pros
- ✓Transparent intro pricing: injectable GLP-1 from $139/month, oral from $199, microdose from $99
- ✓Compounded semaglutide and tirzepatide (injectable or oral) plus brand access to Ozempic, Wegovy, Zepbound
- ✓Only charged if medication is prescribed; no hidden fees
- ✓Free expedited shipping and unlimited board-certified clinician access
- ✓GLP-1 coaching, nutrition guidance, and in-app progress tracking
- ✓LegitScript-certified with named FDA-registered pharmacy partners
- ✓Ships to 49 states (all except Louisiana)
Cons
- ✗Compounded GLP-1s are not FDA-approved finished products (per the site FDA disclaimer)
- ✗Does not ship to Louisiana or to PO boxes
- ✗Introductory pricing rises after the 6-month (or 3-month microdose) plan
- ✗Cash-pay model — insurance billing not indicated
TrimRx
Pros
- ✓Both semaglutide and tirzepatide available
- ✓Compounded GLP-1 access
Cons
- ✗Limited public information on program details
Our Verdict
TrimRx edges out He & She MD with a higher overall score of 9.0/10 and is particularly strong for best overall value. He & She MD remains a solid alternative, especially if you're looking for Transparent low intro-priced GLP-1 (injectable, oral, or microdose) with brand-name access.
Glossary references
Key terms in this article, linked to their canonical definitions.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.