Genesis Health vs Enhance MD
An in-depth comparison of two leading GLP-1 Providers
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Genesis Health
Best for: adults seeking compounded or brand GLP-1s with coaching and annual pricing from $99/mo
Visit Genesis Health →
Enhance MD
Best for: lab-monitored compounded GLP-1 with mandatory video visit
Visit Enhance MD →Genesis Health and Enhance MD are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Genesis Health starts lower at $175/mo versus $212/mo, and Enhance MD edges ahead overall (8.6 vs 7.3 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
Genesis Health
Compounded semaglutide injection. Monthly: $175/mo. Quarterly: $145/mo ($435 billed every 3 months). Bi-Annual: $120/mo ($720 every 6 months). Annual: $99/mo ($1,188/yr). Includes physician consult, medication, and free shipping.
Compounded tirzepatide injection. Monthly: $235/mo. Quarterly: $199/mo ($597 billed every 3 months). Bi-Annual: $175/mo ($1,050 every 6 months). Annual: $125/mo ($1,500/yr). Includes physician consult, medication, and free shipping.
Enhance MD
What’s included
Genesis Health
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Included
Enhance MD
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Not disclosed
Lab work
Included
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Genesis Health
7.3/10
Enhance MD
8.6/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Genesis Health | Enhance MD |
|---|---|---|
| Starting Price | ✓$175/mo | $212/mo |
| Features | ✓8 features | 6 features |
| States Available | Not disclosed | 39 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | ✓ Yes | — |
| FDA Warnings | None | None |
About Genesis Health
Genesis Health is a telehealth platform offering compounded semaglutide and tirzepatide injections alongside brand-name Wegovy, Ozempic, and Zepbound. Monthly plans start at $175/mo for semaglutide and $235/mo for tirzepatide, with annual plans as low as $99/mo and $125/mo respectively. Every plan includes a free physician consultation, personalized dosing, health coaching, active community access, and free expedited shipping. LegitScript certified; medications sourced from audited US-based compounding pharmacies; FSA/HSA eligible.
Read our full Genesis Health review →About Enhance MD
Enhance MD pairs compounded semaglutide and tirzepatide with mandatory baseline metabolic labs at Quest Diagnostics and a synchronous video visit with a board-certified clinician — a more rigorous onboarding than the async-only compounded GLP-1 model most telehealth providers use. Three tiers (Core semaglutide, Advanced tirzepatide, Elite combined) plus aggressive intro pricing ($49 first month on Core).
Read our full Enhance MD review →Pros & Cons
Genesis Health
What we like
- Annual plan as low as $99/mo for semaglutide or $125/mo for tirzepatide
- Offers both compounded and brand-name GLP-1s (Wegovy, Ozempic, Zepbound) in one platform
- Includes health coaching, active community, and free expedited shipping on every plan
- LegitScript certified; medications sourced from audited, licensed US compounding pharmacies
- Same-day provider visits, personalized dosing, and 24/7 care team messaging
Watch-outs
- States served not publicly listed; telehealth coverage unconfirmed for all states
- Monthly starting price ($175 sema / $235 tirz) is mid-market without annual commitment
- Labs not disclosed or included in any published plan tier
- Brand-name GLP-1 pricing not published; insurance or coupon required
- Compounded medications are not FDA-approved
Enhance MD
What we like
- Baseline and ongoing metabolic labs (CMP, lipids, TSH, HbA1c) at Quest every 6 months — rare for compounded GLP-1
- Mandatory video visit with a US-licensed MD or NP before your first prescription — not a pure questionnaire model
- Three tiers, including a combined semaglutide + tirzepatide Elite plan ($322/mo) for patients plateaued on one GLP-1
- Uses LegitScript-certified 503A pharmacies (Tru Meds Rx, Strive Pharmacy, Pharmacy Hub)
- Low first-month intro pricing: $49 Core, $99 Advanced, $189 Elite
- Unlimited clinician messaging and dose-adjustment support included
Watch-outs
- Compounded only — no FDA-approved Ozempic, Wegovy, Zepbound, or Mounjaro
- Not available in 10 states: AL, AR, GA, HI, LA, MS, MO, SC, TN, WV
- Mandatory lab work adds 5–10 days to onboarding vs async-only competitors
- No insurance accepted — cash pay, HSA/FSA eligible
- Intro pricing resets to full tier rate after 30 days — the $49/$99/$189 figures aren't ongoing cost
Our Verdict
Enhance MD edges out Genesis Health with a higher overall score of 8.6/10 and is particularly strong for lab-monitored compounded GLP-1 with mandatory video visit. Genesis Health remains a solid alternative, especially if you're looking for adults seeking compounded or brand GLP-1s with coaching and annual pricing from $99/mo.
Choose Genesis Health if…
You want adults seeking compounded or brand GLP-1s with coaching and annual pricing from $99/mo and a starting price around $175/mo.
Choose Enhance MD if…
You want lab-monitored compounded GLP-1 with mandatory video visit and a starting price around $212/mo.
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Trimi Health
Budget-conscious shoppers
From $99/mo
Get started →Enhance MD
Lab-monitored compounded GLP-1 with mandatory video visit
From $49/mo
Get started →Embody
Lowest first-month entry pricing on compounded GLP-1s
From $99/mo
Get started →Genesis Health vs Enhance MD: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.