Enhance MD vs PreventiveMD
An in-depth comparison of two leading GLP-1 Providers
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Enhance MD
Best for: lab-monitored compounded GLP-1 with mandatory video visit
Visit Enhance MD →
PreventiveMD
Best for: compounded GLP-1s from $83/mo all-in with brand Wegovy and Zepbound upgrade paths
Visit PreventiveMD →Enhance MD and PreventiveMD are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, PreventiveMD starts lower at $83/mo versus $212/mo, and Enhance MD edges ahead overall (8.6 vs 7.8 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
Enhance MD
PreventiveMD
'As low as $83/mo, all-in' — homepage price, live-verified 2026-07-10
'As low as $97/mo, all-in' — homepage price, live-verified 2026-07-10
Medication starts at $149/mo; a separate $49/mo membership fee applies to brand plans
Medication starts at $149/mo; a separate $49/mo membership fee applies to brand plans
Medication starts at $299/mo; a separate $49/mo membership fee applies to brand plans
What’s included
Enhance MD
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Not disclosed
Lab work
Included
Coaching
Not disclosed
PreventiveMD
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Not disclosed
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Enhance MD
8.6/10
PreventiveMD
7.8/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | Enhance MD | PreventiveMD |
|---|---|---|
| Starting Price | $212/mo | ✓$83/mo |
| Features | 6 features | ✓8 features |
| States Available | ✓39 | 36 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | ✓ Yes |
| FSA/HSA Accepted | — | ✓ Yes |
| FDA Warnings | None | None |
About Enhance MD
Enhance MD pairs compounded semaglutide and tirzepatide with mandatory baseline metabolic labs at Quest Diagnostics and a synchronous video visit with a board-certified clinician — a more rigorous onboarding than the async-only compounded GLP-1 model most telehealth providers use. Three tiers (Core semaglutide, Advanced tirzepatide, Elite combined) plus aggressive intro pricing ($49 first month on Core).
Read our full Enhance MD review →About PreventiveMD
PreventiveMD is a physician-guided telehealth platform for GLP-1 weight loss and peptide therapy, offering compounded semaglutide from $83/mo all-in and compounded tirzepatide from $97/mo all-in, plus brand Wegovy, Zepbound, and Foundayo on a membership model. A US-licensed provider reviews each request within 24 hours; approved medication ships to your door with ongoing care through an online portal.
Read our full PreventiveMD review →Pros & Cons
Enhance MD
What we like
- Baseline and ongoing metabolic labs (CMP, lipids, TSH, HbA1c) at Quest every 6 months — rare for compounded GLP-1
- Mandatory video visit with a US-licensed MD or NP before your first prescription — not a pure questionnaire model
- Three tiers, including a combined semaglutide + tirzepatide Elite plan ($322/mo) for patients plateaued on one GLP-1
- Uses LegitScript-certified 503A pharmacies (Tru Meds Rx, Strive Pharmacy, Pharmacy Hub)
- Low first-month intro pricing: $49 Core, $99 Advanced, $189 Elite
- Unlimited clinician messaging and dose-adjustment support included
Watch-outs
- Compounded only — no FDA-approved Ozempic, Wegovy, Zepbound, or Mounjaro
- Not available in 10 states: AL, AR, GA, HI, LA, MS, MO, SC, TN, WV
- Mandatory lab work adds 5–10 days to onboarding vs async-only competitors
- No insurance accepted — cash pay, HSA/FSA eligible
- Intro pricing resets to full tier rate after 30 days — the $49/$99/$189 figures aren't ongoing cost
PreventiveMD
What we like
- Compounded semaglutide from $83/mo and tirzepatide from $97/mo, billed as one all-in monthly price
- Brand Wegovy, Zepbound, and Foundayo (oral GLP-1) available on the same platform
- US-licensed provider reviews requests within 24 hours — no video visit required
- You aren't charged until a provider approves; checkout places an authorization hold only
- LegitScript-certified; works exclusively with state-licensed US 503A compounding pharmacies
- HSA/FSA-eligible with receipts you can submit to your insurer
- Publishes its state-availability list openly on the site
Watch-outs
- Individual compounding pharmacy partners are not publicly named
- Not available in 14 states + DC, including New York, New Jersey, Virginia, and Wisconsin
- Brand Wegovy, Zepbound, and Foundayo require a $49/mo membership fee on top of medication cost
- 'As low as' pricing — actual monthly cost can be higher depending on your plan
- Orders become non-refundable once provider review or pharmacy fulfillment begins
Our Verdict
Enhance MD edges out PreventiveMD with a higher overall score of 8.6/10 and is particularly strong for lab-monitored compounded GLP-1 with mandatory video visit. PreventiveMD remains a solid alternative, especially if you're looking for compounded GLP-1s from $83/mo all-in with brand Wegovy and Zepbound upgrade paths.
Choose Enhance MD if…
You want lab-monitored compounded GLP-1 with mandatory video visit and a starting price around $212/mo.
Choose PreventiveMD if…
You want compounded GLP-1s from $83/mo all-in with brand Wegovy and Zepbound upgrade paths and a starting price around $83/mo.
Ready to start? Vetted GLP-1 providers
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Trimi Health
Budget-conscious shoppers
From $99/mo
Get started →Enhance MD
Lab-monitored compounded GLP-1 with mandatory video visit
From $112/mo
Get started →Embody
Lowest first-month entry pricing on compounded GLP-1s
From $79/mo
Get started →Enhance MD vs PreventiveMD: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.