Cielo vs Vytora Health
In our scoring, Vytora Health edges ahead overall (8.4 vs 7.6 out of 10), and Cielo costs less for compounded semaglutide (about $768 a year less).
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Key differences
- Price
- Cielo $115/mo vs Vytora Health $179/mo for compounded semaglutide (standing prices, no prepay or separate membership listed · about $768 a year less with Cielo)
- Coverage
- Vytora Health 50 states + DC (Cielo doesn't publish a state list)
- Included
- Cielo: medication, shipping; Vytora Health: medication, clinician visits, shipping
Cielo
Best for flat-rate compounded GLP-1 at the lowest 3-month bundle prices
semaglutide
$115
Our score 7.6/10
Vytora Health
Best for compounded or brand-name GLP-1 with named pharmacy partners, 50 states
semaglutide
$179
Our score 8.4/10
We may earn a commission if you sign up through these links. Partner status can affect which provider we feature; it never changes a score or a price.
Costs & coverage
Published prices with their terms attached. Yearly figures are modeled from the standing price and billing cadence. A check mark marks the better side, on like-for-like rows only.
Cielo
Vytora Health
Price
Semaglutide / month
Better on this row: $115/mo
$179/mo
Semaglutide / year (modeled)
Better on this row: $1,380
$2,148
Tirzepatide / month
Better on this row: $180/mo
$249/mo
Tirzepatide / year (modeled)
Better on this row: $2,160
$2,988
Brand Zepbound / Mounjaro / month
Not listed
$1,399/mo
Coverage
State availability
List not published
50 states + DC
Brand-name access listed
Not listed
Zepbound / Mounjaro
Included in the price
Medication, shipping
Medication, clinician visits, shipping
Terms & safety
Price shown
Before intake
Before intake
Cancel anytime
Not disclosed
Yes
Minimum commitment
None
None on monthly plans; 3-month plans are billed every 3 months
Refunds
Not disclosed
'All sales are final' for prescription products; refund requests 'reviewed on a case-by-case basis'
FDA warning letters
None on record
None on record
Provider facts checked
August 2026
October 2026
Every dose and plan: Cielo · Vytora Health
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Which fits your priorities?
Only the points where these two differ, from the table above and each provider’s record.
Choose Cielo if…
- About $768 a year less than Vytora Health for compounded semaglutide at standing prices
- Single flat price across all doses simplifies titration planning
- Corporate address (St. Petersburg, FL) and customer-service phone published
What to weigh up
- No published state list; confirm yours at signup
- No LegitScript, NABP .pharmacy, or HIPAA badge on the home page
Choose Vytora Health if…
- Lists brand-name Zepbound / Mounjaro, which Cielo doesn't price
- Publishes its full state list (50 states + DC)
- Both compounded and brand-name options on one platform
What to weigh up
- About $768 a year more than Cielo for compounded semaglutide
- Brand-name Mounjaro and Zepbound at $1,399/mo are priced at retail; manufacturer self-pay programs are often cheaper
Explore the scoring factors
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
Cielo
7.6/10
Vytora Health
8.4/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
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Get started →Cielo vs Vytora Health: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.