Cielo vs Vytora Health
An in-depth comparison of two leading GLP-1 Providers
WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more
Cielo
Best for flat-rate compounded GLP-1 at the lowest 3-month bundle pricesStarting at $115/mo
Vytora Health
Best for compounded or brand-name GLP-1 with named pharmacy partners, 50 statesStarting at $150/mo
Side-by-Side Comparison
| Feature | Cielo | Vytora Health |
|---|---|---|
| Overall Score | 7.5/10 | ✓8.7/10 |
| Starting Price | ✓$115/mo | $150/mo |
| Editorial Rating | 3.8 ★ /5 | ✓4.4 ★ /5 |
| Features | 8 features | 8 features |
| States Available | 0 | ✓51 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | ✓ Yes |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
Pros & Cons
Cielo
Pros
- ✓Among the lowest 3-month bundle prices in compounded GLP-1 ($115/mo semaglutide)
- ✓Single flat price across all doses simplifies titration planning
- ✓Corporate address (St. Petersburg, FL) and customer-service phone published
Cons
- ✗No LegitScript, NABP .pharmacy, or HIPAA badge on the home page
- ✗Pharmacy partner not named (only 'regulated FDA pharmacy partners')
- ✗State coverage list not published — can't verify all-50-state availability
- ✗Clinical care runs through MD Integrations, a shared third-party network used by many brands
- ✗No brand-name Wegovy or Zepbound option
- ✗Donation page shows 0% next to a 10%-pledge claim — an apparent discrepancy
Vytora Health
Pros
- ✓All 50 states plus DC, with per-state video-vs-audio compliance disclosed
- ✓Both compounded and brand-name options on one platform — uncommon
- ✓LegitScript Approved and HIPAA compliant
- ✓Pharmacy partners named publicly: Vials Pharmacy (TX) and Greenwich Biosciences
- ✓Operating entity disclosed: Wasef Health, PC (Pinellas Park, FL)
- ✓Competitive monthly pricing ($180 sema / $249 tirz) plus a 3-month bundle saving 17%
- ✓Brand-name Mounjaro and Zepbound available at $1,399/mo for FDA-approved options
Cons
- ✗Brand-name Mounjaro/Zepbound at $1,399/mo is near retail — insured patients may do better via LillyDirect Self Pay ($449-$699/mo)
- ✗Compounded tirzepatide at $249/mo is mid-market, above the $149-199 floor
- ✗Dose tiers aren't broken out — 'all doses included' means low-dose patients pay the same as high-dose
- ✗Initial consultation cost not shown on the public pricing page
- ✗Limited per-prescriber state licensure detail
Our Verdict
Vytora Health edges out Cielo with a higher overall score of 8.7/10 and is particularly strong for compounded or brand-name GLP-1 with named pharmacy partners, 50 states. Cielo remains a solid alternative, especially if you're looking for flat-rate compounded GLP-1 at the lowest 3-month bundle prices.
Glossary references
Key terms in this article, linked to their canonical definitions.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
Related comparisons
Continue exploring Cielo and Vytora Health head-to-heads in the same category.
- Cielo vs CoreAge Rx
- Cielo vs TrimRx
- Cielo vs Amazon One Medical
- Vytora Health vs NovoCare Pharmacy
- Vytora Health vs Enhance MD
- Vytora Health vs Noom Med
Or see the full category ranking.
Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.