Cielo vs TrimRx
An in-depth comparison of two leading GLP-1 Providers
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Cielo
Best for flat-rate compounded GLP-1 at the lowest 3-month bundle pricesStarting at $115/mo
TrimRx
Best for best overall valueStarting at $199/mo
Side-by-Side Comparison
| Feature | Cielo | TrimRx |
|---|---|---|
| Overall Score | 7.5/10 | ✓9.0/10 |
| Starting Price | ✓$115/mo | $199/mo |
| Editorial Rating | 3.8 ★ /5 | ✓4.5 ★ /5 |
| Features | ✓8 features | 3 features |
| States Available | 0 | 0 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
Pros & Cons
Cielo
Pros
- ✓Among the lowest 3-month bundle prices in compounded GLP-1 ($115/mo semaglutide)
- ✓Single flat price across all doses simplifies titration planning
- ✓Corporate address (St. Petersburg, FL) and customer-service phone published
Cons
- ✗No LegitScript, NABP .pharmacy, or HIPAA badge on the home page
- ✗Pharmacy partner not named (only 'regulated FDA pharmacy partners')
- ✗State coverage list not published — can't verify all-50-state availability
- ✗Clinical care runs through MD Integrations, a shared third-party network used by many brands
- ✗No brand-name Wegovy or Zepbound option
- ✗Donation page shows 0% next to a 10%-pledge claim — an apparent discrepancy
TrimRx
Pros
- ✓Both semaglutide and tirzepatide available
- ✓Compounded GLP-1 access
Cons
- ✗Limited public information on program details
Our Verdict
TrimRx edges out Cielo with a higher overall score of 9.0/10 and is particularly strong for best overall value. Cielo remains a solid alternative, especially if you're looking for flat-rate compounded GLP-1 at the lowest 3-month bundle prices.
Glossary references
Key terms in this article, linked to their canonical definitions.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
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