24hrDOC vs NewSelf
An in-depth comparison of two leading GLP-1 Providers
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24hrDOC
Best for Cash-pay patients wanting fast, low-cost compounded semaglutide or tirzepatideStarting at $149/mo
NewSelf
Best for lowest-cost compounded GLP-1 with pharmacy quality transparencyStarting at $100/mo
Side-by-Side Comparison
| Feature | 24hrDOC | NewSelf |
|---|---|---|
| Overall Score | 7.1/10 | ✓7.8/10 |
| Starting Price | $149/mo | ✓$100/mo |
| Editorial Rating | 3.6 ★ /5 | ✓3.9 ★ /5 |
| Features | ✓8 features | 6 features |
| States Available | 0 | ✓49 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
Pros & Cons
24hrDOC
Pros
- ✓Low compounded semaglutide price, around 149 per month
- ✓Fast model: 10-minute assessment, Rx within 45 minutes
- ✓Injectable and oral semaglutide plus tirzepatide options
- ✓24/7 availability with unlimited provider messaging
Cons
- ✗Compounded only, not FDA-approved branded GLP-1s
- ✗Self-pay only, no insurance accepted
- ✗States served not disclosed on the site
- ✗Fast-prescribing model offers less in-depth clinical workup
NewSelf
Pros
- ✓Semaglutide+ from $99.97/mo — among the lowest prices in the dataset
- ✓All dosages at the same price — no price escalation as dose increases
- ✓LegitScript certified with 503A licensed pharmacies
- ✓Third-party potency, sterility, and endotoxicity testing
- ✓48 states + Puerto Rico coverage
- ✓B12/B6 + Glycine enhanced formulations
- ✓No membership fees
Cons
- ✗Not available in Mississippi and Louisiana
- ✗Compounded only — no brand-name options
- ✗Site also promotes AI health optimization and longevity (broader platform)
Our Verdict
NewSelf edges out 24hrDOC with a higher overall score of 7.8/10 and is particularly strong for lowest-cost compounded GLP-1 with pharmacy quality transparency. 24hrDOC remains a solid alternative, especially if you're looking for Cash-pay patients wanting fast, low-cost compounded semaglutide or tirzepatide.
Glossary references
Key terms in this article, linked to their canonical definitions.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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- 24hrDOC vs TrimRx
- 24hrDOC vs Amazon One Medical
- NewSelf vs NovoCare Pharmacy
- NewSelf vs Vytora Health
- NewSelf vs Enhance MD
Or see the full category ranking.
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