24hrDOC vs He & She MD
An in-depth comparison of two leading GLP-1 Providers
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24hrDOC
Best for Cash-pay patients wanting fast, low-cost compounded semaglutide or tirzepatideStarting at $149/mo
He & She MD
Best for Transparent low intro-priced GLP-1 (injectable, oral, or microdose) with brand-name accessStarting at $99/mo
Side-by-Side Comparison
| Feature | 24hrDOC | He & She MD |
|---|---|---|
| Overall Score | 7.1/10 | ✓7.4/10 |
| Starting Price | $149/mo | ✓$99/mo |
| Editorial Rating | 3.6 ★ /5 | ✓3.7 ★ /5 |
| Features | 8 features | 8 features |
| States Available | 0 | ✓50 |
| Compounded | ✓ Yes | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
Pros & Cons
24hrDOC
Pros
- ✓Low compounded semaglutide price, around 149 per month
- ✓Fast model: 10-minute assessment, Rx within 45 minutes
- ✓Injectable and oral semaglutide plus tirzepatide options
- ✓24/7 availability with unlimited provider messaging
Cons
- ✗Compounded only, not FDA-approved branded GLP-1s
- ✗Self-pay only, no insurance accepted
- ✗States served not disclosed on the site
- ✗Fast-prescribing model offers less in-depth clinical workup
He & She MD
Pros
- ✓Transparent intro pricing: injectable GLP-1 from $139/month, oral from $199, microdose from $99
- ✓Compounded semaglutide and tirzepatide (injectable or oral) plus brand access to Ozempic, Wegovy, Zepbound
- ✓Only charged if medication is prescribed; no hidden fees
- ✓Free expedited shipping and unlimited board-certified clinician access
- ✓GLP-1 coaching, nutrition guidance, and in-app progress tracking
- ✓LegitScript-certified with named FDA-registered pharmacy partners
- ✓Ships to 49 states (all except Louisiana)
Cons
- ✗Compounded GLP-1s are not FDA-approved finished products (per the site FDA disclaimer)
- ✗Does not ship to Louisiana or to PO boxes
- ✗Introductory pricing rises after the 6-month (or 3-month microdose) plan
- ✗Cash-pay model — insurance billing not indicated
Our Verdict
He & She MD edges out 24hrDOC with a higher overall score of 7.4/10 and is particularly strong for Transparent low intro-priced GLP-1 (injectable, oral, or microdose) with brand-name access. 24hrDOC remains a solid alternative, especially if you're looking for Cash-pay patients wanting fast, low-cost compounded semaglutide or tirzepatide.
Glossary references
Key terms in this article, linked to their canonical definitions.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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Or see the full category ranking.
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