1st Optimal vs Superior Remedies
An in-depth comparison of two leading GLP-1 Providers
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1st Optimal
Best for: GLP-1 therapy within a lab-driven functional-medicine program
Visit 1st Optimal →
Superior Remedies
Best for: readers who want a lower-dose GLP-1 microdose protocol for body composition rather than maximum weight loss
Visit Superior Remedies →1st Optimal and Superior Remedies are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Superior Remedies starts at $249/mo, and 1st Optimal edges ahead overall (6.7 vs 6.4 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
1st Optimal
Pricing not publicly listed.
Superior Remedies
Semaglutide program, listed at $299/mo on the treatment page
Tirzepatide program, listed at $399/mo on the treatment page
GLP-1 Microdose program at $249/mo; the site never says which molecule it uses
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What’s included
1st Optimal
What the monthly price covers
Medication
Not disclosed
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Included
Superior Remedies
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
1st Optimal
6.7/10
Superior Remedies
6.4/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | 1st Optimal | Superior Remedies |
|---|---|---|
| Starting Price | — | $249/mo |
| Features | 8 features | 8 features |
| States Available | Not disclosed | 7 |
| Compounded | — | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About 1st Optimal
1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets. Its model pairs prescription GLP-1 therapy with at-home lab testing, blood-work interpretation, unlimited coaching, and personalized protocols framed around long-term weight loss and longevity. Care is delivered virtually by credentialed providers, and treatments ship to the home with no long-term contracts. The site does not publish monthly pricing or a state list.
Read our full 1st Optimal review →About Superior Remedies
Superior Remedies is a Delaware-registered telehealth practice selling provider-supervised compounded GLP-1 programs: semaglutide, tirzepatide, and a lower-dose microdose protocol aimed at body composition rather than maximum weight loss. Pricing is flat monthly with no consultation fee and no dose-change surcharge, and nothing is charged if a provider does not approve you. Its own FAQ limits service to seven states even though the homepage banner advertises all 50.
Read our full Superior Remedies review →Pros & Cons
1st Optimal
What we like
- Offers both semaglutide and tirzepatide with injectable and oral formats
- Functional-medicine approach with at-home labs and blood-work interpretation
- Unlimited coaching and ongoing support included
- No long-term contracts
- Board-certified doctors and nurse practitioners referenced
Watch-outs
- No public monthly pricing disclosed
- No published state availability list
- Compounded vs branded sourcing not clarified on site
- Pricing only revealed after quiz or consultation
Superior Remedies
What we like
- Flat monthly price covers medication, provider oversight and shipping, with no consultation fee and no dose-change surcharge
- Nothing is charged if a provider does not approve you, stated on the homepage and in the footer policy
- Publishes every program price on its treatment pages before you enter the intake quiz
- States in writing that compounded medications are not FDA-approved and have not been independently verified for safety, efficacy or quality
- Carries a lower-dose microdose protocol aimed at body composition, which most GLP-1 telehealth menus do not offer
- Intake screens for medullary thyroid carcinoma, MEN 2, pregnancy and other contraindications before provider review
- No FDA warning letter on record for Superior Remedies LLC as of August 2026
- Publishes a street address, a phone number and clinical hours
Watch-outs
- The homepage advertises 'From $149/mo' but no published program costs $149; the cheapest is the $249 microdose
- Banner claims telehealth in all 50 states while its own FAQ and contact page limit service to seven
- Never names its compounding pharmacy anywhere public, including the terms, privacy and HIPAA notices
- Three conflicting cancellation terms: 'cancel anytime', 30 days' notice, and 48 hours before the processing date
- Terms require you to waive the right to have your prescription filled at a pharmacy of your choice
- Consultations, memberships and dispensed medication are non-refundable once services begin
- The intake quiz asks 20 questions before your name and presents a 92% success probability
- The microdose program never says which GLP-1 molecule it uses
Our Verdict
1st Optimal edges out Superior Remedies with a higher overall score of 6.7/10 and is particularly strong for GLP-1 therapy within a lab-driven functional-medicine program. Superior Remedies remains a solid alternative, especially if you're looking for readers who want a lower-dose GLP-1 microdose protocol for body composition rather than maximum weight loss.
Choose 1st Optimal if…
You want GLP-1 therapy within a lab-driven functional-medicine program.
Choose Superior Remedies if…
You want readers who want a lower-dose GLP-1 microdose protocol for body composition rather than maximum weight loss and a starting price around $249/mo.
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Care Bare Rx
LGBTQ+-inclusive compounded GLP-1 telehealth
From $199/mo
Get started →Enhance MD
Lab-monitored compounded GLP-1 with mandatory video visit
From $112/mo
Get started →MEDVi
Switching between compounded and brand-name GLP-1 through one provider
From $99/mo
Get started →1st Optimal vs Superior Remedies: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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