1st Optimal vs Revel RX
An in-depth comparison of two leading GLP-1 Providers
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1st Optimal
Best for: Patients wanting GLP-1 therapy within a lab-driven functional-medicine program
Visit 1st Optimal →
Revel RX
Best for: flat-rate compounded GLP-1 from $89/mo with LegitScript-verified telehealth care
Visit Revel RX →1st Optimal and Revel RX are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Revel RX starts at $89/mo, and Revel RX edges ahead overall (7.9 vs 6.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.
Pricing
1st Optimal
Pricing not publicly listed.
Revel RX
Flat $89/mo for every dose tier; includes consultation, medication, and overnight cold shipping
Flat $155/mo for every dose tier; includes consultation, medication, and overnight cold shipping
What’s included
1st Optimal
Inclusions not disclosed.
Revel RX
What the monthly price covers
Medication
Included
Provider visits
Included
Shipping
Included
Lab work
Not disclosed
Coaching
Not disclosed
Score breakdown
Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.
1st Optimal
6.7/10
Revel RX
7.9/10
Value25%
Effectiveness25%
User Experience15%
Trust & Safety15%
Accessibility10%
Support10%
Features & Coverage
| Feature | 1st Optimal | Revel RX |
|---|---|---|
| Starting Price | — | $89/mo |
| Features | 8 features | 8 features |
| States Available | Not disclosed | Not disclosed |
| Compounded | — | ✓ Yes |
| Brand Name | — | — |
| FSA/HSA Accepted | — | — |
| FDA Warnings | None | None |
About 1st Optimal
1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets. Its model pairs prescription GLP-1 therapy with at-home lab testing, blood-work interpretation, unlimited coaching, and personalized protocols framed around long-term weight loss and longevity. Care is delivered virtually by credentialed providers, and treatments ship to the home with no long-term contracts. The site does not publish monthly pricing or a state list.
Read our full 1st Optimal review →About Revel RX
Revel RX is a Michigan-based telehealth weight-loss platform offering compounded semaglutide at $89/month and compounded tirzepatide at $155/month — flat-rate at every dose tier. Clinical services are handled by MD Integrations (an independent medical group) and medications ship from Manifest Pharmacy and Red Rock Home Pharmacy, U.S.-licensed 503A and 503B compounding facilities. Every plan includes consultation, medication, and free overnight cold shipping with no hidden fees. LegitScript verified, BBB A+ accredited, and HIPAA compliant. Compounded medications are not FDA-approved.
Read our full Revel RX review →Pros & Cons
1st Optimal
What we like
- Offers both semaglutide and tirzepatide with injectable and oral formats
- Functional-medicine approach with at-home labs and blood-work interpretation
- Unlimited coaching and ongoing support included
- No long-term contracts
- Board-certified doctors and nurse practitioners referenced
Watch-outs
- No public monthly pricing disclosed
- No published state availability list
- Compounded vs branded sourcing not clarified on site
- Pricing only revealed after quiz or consultation
Revel RX
What we like
- Industry-low flat pricing: $89/mo for compounded semaglutide and $155/mo for tirzepatide at every dose
- LegitScript verified and BBB accredited with an A+ rating — above-average trust signals for a compounded platform
- Named pharmacy partners: Manifest Pharmacy and Red Rock Home Pharmacy (503A + 503B facilities)
- Free overnight cold shipping included; no hidden fees or dose-based price increases
- Clinical review by MD Integrations, an independent medical group, before any prescription is issued
Watch-outs
- States served are not publicly listed; eligible states requires completing intake to confirm coverage
- No labs, coaching, or ongoing health support disclosed in any public materials
- Compounded medications are not FDA-approved (site discloses this)
- Newer brand with limited public patient reviews or Trustpilot rating
- Pharmacy partners named but no accreditation details (PCAB, 503B cGMP) published on the site
Our Verdict
Revel RX edges out 1st Optimal with a higher overall score of 7.9/10 and is particularly strong for flat-rate compounded GLP-1 from $89/mo with LegitScript-verified telehealth care. 1st Optimal remains a solid alternative, especially if you're looking for Patients wanting GLP-1 therapy within a lab-driven functional-medicine program.
Choose 1st Optimal if…
You want Patients wanting GLP-1 therapy within a lab-driven functional-medicine program.
Choose Revel RX if…
You want flat-rate compounded GLP-1 from $89/mo with LegitScript-verified telehealth care and a starting price around $89/mo.
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Trimi Health
Budget-conscious shoppers
From $99/mo
Get started →Enhance MD
Lab-monitored compounded GLP-1 with mandatory video visit
From $49/mo
Get started →Embody
Lowest first-month entry pricing on compounded GLP-1s
From $99/mo
Get started →1st Optimal vs Revel RX: FAQ
Key terms, explained
New to GLP-1s? Tap any term for a quick, plain-English definition.
- Semaglutide · Drugs and brands
- Tirzepatide · Drugs and brands
- Compounded GLP-1 · Pharmacy and drug forms
- 503A pharmacy · Pharmacy and drug forms
- PCAB accreditation · Pharmacy and drug forms
- Prior authorization (PA) · Insurance and regulatory
- Off-label use · Insurance and regulatory
- FDA Drug Shortage List · Insurance and regulatory
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