Always verify pricing and state availability on the provider's website before signing up.How our reviews work →

1st Optimal vs Revel RX

An in-depth comparison of two leading GLP-1 Providers

WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more

By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
1st Optimal logo

1st Optimal

6.7
★★★☆☆3.4/5

Best for: GLP-1 therapy within a lab-driven functional-medicine program

Visit 1st Optimal
VS
Revel RX logo

Revel RX

8.0
★★★★4/5

Best for: flat-rate compounded GLP-1 from $89/mo, LegitScript-verified telehealth

Visit Revel RX

1st Optimal and Revel RX are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, Revel RX starts lower at $89/mo versus $99/mo, and Revel RX edges ahead overall (8.0 vs 6.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

1st Optimal

Weight Loss Care membership — medication not includedBrand-name
$99/mo
semaglutide

Care membership only — the GLP-1 medication is billed separately and is not priced.

Revel RX

All dosesCompounded
$89/mo
semaglutide

Flat $89/mo for every dose tier; includes consultation, medication, and overnight cold shipping

All dosesCompounded
$155/mo
tirzepatide

Flat $155/mo for every dose tier; includes consultation, medication, and overnight cold shipping

Get alerted when GLP-1 prices drop

Join the GLP-1 price-watch list — we re-verify 490+ providers' prices on their own sites and email you when tracked prices move.

What’s included

1st Optimal

What the monthly price covers

Medication

Not disclosed

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Included

Revel RX

What the monthly price covers

Medication

Included

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

1st Optimal

6.7/10

Overall

Revel RX

8.0/10

Value25%

6.5A
vs
B
9.0

Effectiveness25%

7.0A
vs
B
8.0

User Experience15%

6.5A
vs
B
8.0

Trust & Safety15%

6.5A
vs
B
7.8

Accessibility10%

6.5A
vs
B
6.5

Support10%

7.4A
vs
B
7.4

Features & Coverage

Feature1st OptimalRevel RX
Starting Price$99/mo$89/mo
Features8 features8 features
States AvailableNot disclosedNot disclosed
Compounded✓ Yes
Brand Name✓ Yes
FSA/HSA Accepted
FDA WarningsNoneNone

About 1st Optimal

1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets. Its model pairs prescription GLP-1 therapy with at-home lab testing, blood-work interpretation, unlimited coaching, and personalized protocols framed around long-term weight loss and longevity. Care is delivered virtually by credentialed providers, and treatments ship to the home with no long-term contracts. The site does not publish monthly pricing or a state list.

Read our full 1st Optimal review →

About Revel RX

Revel RX is a Michigan-based telehealth weight-loss platform offering compounded semaglutide at $89/month and compounded tirzepatide at $155/month — flat-rate at every dose tier. Clinical services are handled by MD Integrations (an independent medical group) and medications ship from Manifest Pharmacy and Red Rock Home Pharmacy, U.S.-licensed 503A and 503B compounding facilities. Every plan includes consultation, medication, and free overnight cold shipping with no hidden fees. LegitScript verified, BBB A+ accredited, and HIPAA compliant. Compounded medications are not FDA-approved.

Read our full Revel RX review →

Pros & Cons

1st Optimal

What we like

  • Offers both semaglutide and tirzepatide with injectable and oral formats
  • Functional-medicine approach with at-home labs and blood-work interpretation
  • Unlimited coaching and ongoing support included
  • No long-term contracts
  • Board-certified doctors and nurse practitioners referenced

Watch-outs

  • No public monthly pricing disclosed
  • No published state availability list
  • Compounded vs branded sourcing not clarified on site
  • Pricing only revealed after quiz or consultation

Revel RX

What we like

  • Industry-low flat pricing: $89/mo for compounded semaglutide and $155/mo for tirzepatide at every dose
  • LegitScript verified and BBB accredited with an A+ rating — above-average trust signals for a compounded platform
  • Named pharmacy partners: Manifest Pharmacy and Red Rock Home Pharmacy (503A + 503B facilities)
  • Free overnight cold shipping included; no hidden fees or dose-based price increases
  • Clinical review by MD Integrations, an independent medical group, before any prescription is issued

Watch-outs

  • States served are not publicly listed; eligible states requires completing intake to confirm coverage
  • No labs, coaching, or ongoing health support disclosed in any public materials
  • Compounded medications are not FDA-approved (site discloses this)
  • Newer brand with limited public patient reviews or Trustpilot rating
  • Pharmacy partners named but no accreditation details (PCAB, 503B cGMP) published on the site

Our Verdict

Winner: Revel RX

Revel RX edges out 1st Optimal with a higher overall score of 8.0/10 and is particularly strong for flat-rate compounded GLP-1 from $89/mo, LegitScript-verified telehealth. 1st Optimal remains a solid alternative, especially if you're looking for GLP-1 therapy within a lab-driven functional-medicine program.

Choose 1st Optimal if…

You want GLP-1 therapy within a lab-driven functional-medicine program and a starting price around $99/mo.

Choose Revel RX if…

You want flat-rate compounded GLP-1 from $89/mo, LegitScript-verified telehealth and a starting price around $89/mo.

Ready to start? Vetted GLP-1 providers

Vetted telehealth providers that prescribe GLP-1 online.

No insurance needed · vetted by our editors

WeightLossRankings.org is reader-supported. When you buy through links on our site, we may earn an affiliate commission. Learn more

8.3

Found

Mainstream telehealth GLP-1 access

7.1

Bodybuilding Health+

Fitness-brand compounded GLP-1 with hormone and performance programs

7.4

Brightmeds

Compounded or brand GLP-1 bundled with TRT and peptides for men

1st Optimal vs Revel RX: FAQ

Key terms, explained

New to GLP-1s? Tap any term for a quick, plain-English definition.

Continue exploring 1st Optimal and Revel RX head-to-heads in the same category.

Or see the full category ranking.

Wegovy®, Ozempic®, and Rybelsus® are trademarks of Novo Nordisk A/S. Mounjaro® and Zepbound® are trademarks of Eli Lilly and Company. All other product names and trademarks referenced on this page belong to their respective owners. WeightLossRankings.org is not affiliated with any pharmaceutical manufacturer. See trademark disclaimer.