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1st Optimal vs Nuform Health

An in-depth comparison of two leading GLP-1 Providers

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By Eli Marsden · Founding Editor
Editorially reviewed & fact-checked against primary sources · How we verify contentLast reviewed
1st Optimal logo

1st Optimal

6.7
★★★☆☆3.4/5

Best for: GLP-1 therapy within a lab-driven functional-medicine program

Visit 1st Optimal
VS
Nuform Health logo

Nuform Health

7.1
★★★3.6/5

Best for: non-GLP-1 weight management

Visit Nuform Health

1st Optimal and Nuform Health are both GLP-1 Providers competing for the same patients, but they make different trade-offs on price, coverage, and what's included. In our scoring, 1st Optimal starts lower at $99/mo versus $129/mo, and Nuform Health edges ahead overall (7.1 vs 6.7 out of 10). Below we break down pricing, what each plan covers, the six-dimension score, pros and cons, and exactly who should pick which.

Pricing

1st Optimal

Weight Loss Care membership — medication not includedBrand-name
$99/mo
semaglutide

Care membership only — the GLP-1 medication is billed separately and is not priced.

Nuform Health

GLP Vitamin Blend — 3-month starter kit ($389 charged)Compounded
$129/mo

⛔ THERE IS NO MONTHLY OPTION AT ALL. Nuform sells only multi-month blocks and divides each into a '/mo' headline: 'Billed in 3 month increments.' The figure recorded here is Nuform's own per-month division; the money actually charged is $389 up front. Full ladder on this line: STARTER KIT $389 (3 month plan, $129/mo), MAINTENANCE KIT $589 (5 month plan, $117/mo), MAINTENANCE KIT $360 (4 month plan, $90/mo). ⚠ THE MOLECULE IS NOT NAMED. The product is labelled only 'GLP VITAMIN BLEND' and the page states 'Compounded GLP vitamin blend formulary may vary dependent health care provider recommendations', so no drug field is set on this row rather than assuming semaglutide.

GLP+GIP Vitamin Blend — 2.5-month starter kit ($499 charged)Compounded
$199/mo

⛔ THERE IS NO MONTHLY OPTION AT ALL. Nuform sells only multi-month blocks and divides each into a '/mo' headline: 'Billed in 2.5 month increments.' The figure recorded here is Nuform's own per-month division; the money actually charged is $499 up front. Full ladder: STARTER KIT $499 (2.5 month plan, $199/mo), MAINTENANCE KIT $780 (4.5 month plan, $173/mo), MAINTENANCE KIT $980 (6.5 month plan, $150/mo). The page states 'GLP+GIP is recommended to be taken 2.5, 4.5, & 6.5 months at a time to achieve optimal peak results.' ⚠ Molecule not named — labelled only 'GLP+GIP VITAMIN BLEND', so no drug field is set.

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What’s included

1st Optimal

What the monthly price covers

Medication

Not disclosed

Provider visits

Included

Shipping

Included

Lab work

Not disclosed

Coaching

Included

Nuform Health

What the monthly price covers

Medication

Included

Provider visits

Billed separately

Shipping

Not disclosed

Lab work

Not disclosed

Coaching

Not disclosed

Score breakdown

Both providers are scored on the same six-dimension framework. The gradient bar marks the stronger side on each dimension.

1st Optimal

6.7/10

Overall

Nuform Health

7.1/10

Value25%

6.5A
vs
B
6.5

Effectiveness25%

7.0A
vs
B
7.5

User Experience15%

6.5A
vs
B
7.0

Trust & Safety15%

6.5A
vs
B
7.0

Accessibility10%

6.5A
vs
B
7.5

Support10%

7.4A
vs
B
7.4

Features & Coverage

Feature1st OptimalNuform Health
Starting Price$99/mo$129/mo
Features8 features0 features
States AvailableNot disclosedNot disclosed
Compounded✓ Yes
Brand Name✓ Yes
FSA/HSA Accepted
FDA WarningsNoneNone

About 1st Optimal

1st Optimal is a Michigan-based telehealth and functional-medicine platform offering GLP-1 weight loss medications, including semaglutide and tirzepatide, as once-weekly injections or daily oral tablets. Its model pairs prescription GLP-1 therapy with at-home lab testing, blood-work interpretation, unlimited coaching, and personalized protocols framed around long-term weight loss and longevity. Care is delivered virtually by credentialed providers, and treatments ship to the home with no long-term contracts. The site does not publish monthly pricing or a state list.

Read our full 1st Optimal review →

About Nuform Health

Telehealth wellness brand selling compounded GLP and GLP+GIP vitamin blends for weight loss. It publishes no monthly option — everything is sold in blocks of 2.5 to 6.5 months, billed up front, with the price then divided into a per-month headline. It never names the molecule in either product.

Read our full Nuform Health review →

Pros & Cons

1st Optimal

What we like

  • Offers both semaglutide and tirzepatide with injectable and oral formats
  • Functional-medicine approach with at-home labs and blood-work interpretation
  • Unlimited coaching and ongoing support included
  • No long-term contracts
  • Board-certified doctors and nurse practitioners referenced

Watch-outs

  • No public monthly pricing disclosed
  • No published state availability list
  • Compounded vs branded sourcing not clarified on site
  • Pricing only revealed after quiz or consultation

Nuform Health

What we like

  • Telehealth convenience
  • Physician-supervised program

Watch-outs

  • GLP-1 medications not currently offered

Our Verdict

Winner: Nuform Health

Nuform Health edges out 1st Optimal with a higher overall score of 7.1/10 and is particularly strong for non-GLP-1 weight management. 1st Optimal remains a solid alternative, especially if you're looking for GLP-1 therapy within a lab-driven functional-medicine program.

Choose 1st Optimal if…

You want GLP-1 therapy within a lab-driven functional-medicine program and a starting price around $99/mo.

Choose Nuform Health if…

You want non-GLP-1 weight management and a starting price around $129/mo.

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6.9

Try Ageless

Lowest-tier compounded GLP-1 in injection, troche and sublingual forms

7.3

Sunlight

Compounded GLP-1 with unlimited telehealth visits and free shipping

7.4

MadeMed

Compounded GLP-1 in both injection and oral forms

1st Optimal vs Nuform Health: FAQ

1st Optimal is cheaper. Its lowest ongoing monthly cash price is $99/mo, compared with $129/mo for Nuform Health. We compare standing (not first-month promo) prices so the figures reflect what you'd actually pay month to month.
Nuform Health scores higher overall at 7.1/10 versus 6.7/10, and is particularly strong for non-GLP-1 weight management. That said, 1st Optimal is a better fit if you want GLP-1 therapy within a lab-driven functional-medicine program.
Neither 1st Optimal nor Nuform Health publicly lists its exact state availability. Most national GLP-1 telehealth providers operate in the majority of states — confirm your state is covered during sign-up.
Neither 1st Optimal nor Nuform Health is currently an affiliate partner, so we earn no commission from either. We rank all providers editorially using the same six-dimension framework and disclose any commercial relationships.

Key terms, explained

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Continue exploring 1st Optimal and Nuform Health head-to-heads in the same category.

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